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Oncogenic CDK13 mutations impede nuclear RNA surveillance.
Insco ML, Abraham BJ, Dubbury SJ, Kaltheuner IH, Dust S, Wu C, Chen KY, Liu D, Bellaousov S, Cox AM, Martin BJE, Zhang T, Ludwig CG, Fabo T, Modhurima R, Esgdaille DE, Henriques T, Brown KM, Chanock SJ, Geyer M, Adelman K, Sharp PA, Young RA, Boutz PL, Zon LI. Insco ML, et al. Science. 2023 Apr 21;380(6642):eabn7625. doi: 10.1126/science.abn7625. Epub 2023 Apr 21. Science. 2023. PMID: 37079685 Free PMC article.
Gain-of-Function Genetic Alterations of G9a Drive Oncogenesis.
Kato S, Weng QY, Insco ML, Chen KY, Muralidhar S, Pozniak J, Diaz JMS, Drier Y, Nguyen N, Lo JA, van Rooijen E, Kemeny LV, Zhan Y, Feng Y, Silkworth W, Powell CT, Liau BB, Xiong Y, Jin J, Newton-Bishop J, Zon LI, Bernstein BE, Fisher DE. Kato S, et al. Among authors: insco ml. Cancer Discov. 2020 Jul;10(7):980-997. doi: 10.1158/2159-8290.CD-19-0532. Epub 2020 Apr 8. Cancer Discov. 2020. PMID: 32269030 Free PMC article.
Voices: Challenges and opportunities in RNA biology.
Chen LL, Ingolia NT, Insco ML, Li JB, Oberdoerffer S, Weeks KM. Chen LL, et al. Among authors: insco ml. Cell Chem Biol. 2024 Jan 18;31(1):10-13. doi: 10.1016/j.chembiol.2023.12.015. Cell Chem Biol. 2024. PMID: 38242091
Specific oncogene activation of the cell of origin in mucosal melanoma.
Babu S, Chen J, Robitschek E, Baron CS, McConnell A, Wu C, Dedeilia A, Sade-Feldman M, Modhurima R, Manos MP, Chen KY, Cox AM, Ludwig CG, Yang J, Kellis M, Buchbinder EI, Hacohen N, Boland GM, Abraham BJ, Liu D, Zon LI, Insco ML. Babu S, et al. Among authors: insco ml. bioRxiv [Preprint]. 2024 Apr 26:2024.04.22.590595. doi: 10.1101/2024.04.22.590595. bioRxiv. 2024. PMID: 38712250 Free PMC article. Preprint.