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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1983 1
1987 1
1988 2
1989 3
1992 8
1993 9
1994 5
1995 5
1996 6
1997 9
1998 11
1999 8
2000 23
2001 16
2002 15
2003 16
2004 19
2005 13
2006 32
2007 33
2008 26
2009 27
2010 40
2011 33
2012 61
2013 68
2014 72
2015 74
2016 69
2017 63
2018 61
2019 66
2020 55
2021 41
2022 27
2023 32
2024 31
2025 2

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957 results

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1 article found by citation matching

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Page 1
[Epigenetics of polycystic ovary syndrome].
Concha C F, Sir P T, Recabarren SE, Pérez B F. Concha C F, et al. Rev Med Chil. 2017 Jul;145(7):907-915. doi: 10.4067/s0034-98872017000700907. Rev Med Chil. 2017. PMID: 29182200 Free article. Review. Spanish.
It is frequently associated with obesity and insulin resistance. Recently, epigenetic mechanisms have been involved in the pathogenesis of PCOS. Several studies showed that methylation in DNA and miRNAs is altered in women with PCOS in blood, serum, adipose t …
It is frequently associated with obesity and insulin resistance. Recently, epigenetic mechanisms have been involved in the pathogenes …
Epigenetic regulation of insulin action and secretion - role in the pathogenesis of type 2 diabetes.
Ling C. Ling C. J Intern Med. 2020 Aug;288(2):158-167. doi: 10.1111/joim.13049. Epub 2020 May 3. J Intern Med. 2020. PMID: 32363639 Free article. Review.
Numerous studies have found differential DNA methylation and gene expression in skeletal muscle, adipose tissue, the liver and pancreatic islets from subjects with T2D compared with nondiabetic controls. For example, PDX1 has increased DNA me …
Numerous studies have found differential DNA methylation and gene expression in skeletal muscle, adipose tissue, …
A comprehensive epigenome atlas reveals DNA methylation regulating skeletal muscle development.
Yang Y, Fan X, Yan J, Chen M, Zhu M, Tang Y, Liu S, Tang Z. Yang Y, et al. Nucleic Acids Res. 2021 Feb 22;49(3):1313-1329. doi: 10.1093/nar/gkaa1203. Nucleic Acids Res. 2021. PMID: 33434283 Free PMC article.
DNA methylation is important for the epigenetic regulation of gene expression and plays a critical role in mammalian development. However, the dynamic regulation of genome-wide DNA methylation in skeletal muscle development …
DNA methylation is important for the epigenetic regulation of gene expression and plays a critical role i …
Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements.
Battaglia S, Dong K, Wu J, Chen Z, Najm FJ, Zhang Y, Moore MM, Hecht V, Shoresh N, Bernstein BE. Battaglia S, et al. Nat Genet. 2022 Oct;54(10):1504-1513. doi: 10.1038/s41588-022-01188-8. Epub 2022 Oct 4. Nat Genet. 2022. PMID: 36195755 Free PMC article.
Here, we apply targeted nanopore sequencing to profile chromatin accessibility and DNA methylation on contiguous ~100-kb DNA molecules that span loci relevant to development, immunity and imprinting. ...These include a segmental duplication that stabilizes th …
Here, we apply targeted nanopore sequencing to profile chromatin accessibility and DNA methylation on contiguous ~100-kb DN …
Insulin gene expression is regulated by DNA methylation.
Kuroda A, Rauch TA, Todorov I, Ku HT, Al-Abdullah IH, Kandeel F, Mullen Y, Pfeifer GP, Ferreri K. Kuroda A, et al. PLoS One. 2009 Sep 9;4(9):e6953. doi: 10.1371/journal.pone.0006953. PLoS One. 2009. PMID: 19742322 Free PMC article.
BACKGROUND: Insulin is a critical component of metabolic control, and as such, insulin gene expression has been the focus of extensive study. ...However, only recently have other components of insulin gene expression been in …
BACKGROUND: Insulin is a critical component of metabolic control, and as such, insulin gene expression ha …
DNA methylation analysis in nonalcoholic fatty liver disease suggests distinct disease-specific and remodeling signatures after bariatric surgery.
Ahrens M, Ammerpohl O, von Schönfels W, Kolarova J, Bens S, Itzel T, Teufel A, Herrmann A, Brosch M, Hinrichsen H, Erhart W, Egberts J, Sipos B, Schreiber S, Häsler R, Stickel F, Becker T, Krawczak M, Röcken C, Siebert R, Schafmayer C, Hampe J. Ahrens M, et al. Cell Metab. 2013 Aug 6;18(2):296-302. doi: 10.1016/j.cmet.2013.07.004. Cell Metab. 2013. PMID: 23931760 Free article.
Liver samples from morbidly obese patients (n = 45) with all stages of NAFLD and controls (n = 18) were analyzed by array-based DNA methylation and mRNA expression profiling. NAFLD-specific expression and methylation differences were seen for ni …
Liver samples from morbidly obese patients (n = 45) with all stages of NAFLD and controls (n = 18) were analyzed by array-based DNA …
Aberrant methylation underlies insulin gene expression in human insulinoma.
Karakose E, Wang H, Inabnet W, Thakker RV, Libutti S, Fernandez-Ranvier G, Suh H, Stevenson M, Kinoshita Y, Donovan M, Antipin Y, Li Y, Liu X, Jin F, Wang P, Uzilov A, Argmann C, Schadt EE, Stewart AF, Scott DK, Lambertini L. Karakose E, et al. Nat Commun. 2020 Oct 15;11(1):5210. doi: 10.1038/s41467-020-18839-1. Nat Commun. 2020. PMID: 33060578 Free PMC article.
Human insulinomas are rare, benign, slowly proliferating, insulin-producing beta cell tumors that provide a molecular "recipe" or "roadmap" for pathways that control human beta cell regeneration. ...We find a remarkably consistent, abnormal methylation patter …
Human insulinomas are rare, benign, slowly proliferating, insulin-producing beta cell tumors that provide a molecular "recipe" or "ro …
Expression of IGFBP7 in acute leukemia is regulated by DNA methylation.
Heesch S, Bartram I, Neumann M, Reins J, Mossner M, Schlee C, Stroux A, Haferlach T, Goekbuget N, Hoelzer D, Hofmann WK, Thiel E, Baldus CD. Heesch S, et al. Cancer Sci. 2011 Jan;102(1):253-9. doi: 10.1111/j.1349-7006.2010.01760.x. Epub 2010 Oct 29. Cancer Sci. 2011. PMID: 21040219 Free article.
Moreover, in acute T-lymphoblastic leukemia (T-ALL), high IGFBP7 expression predicts primary therapy resistance. In order to elucidate the mechanisms underlying aberrant IGFBP7 expression, we used pyrosequencing technology to investigate the DNA methylatio …
Moreover, in acute T-lymphoblastic leukemia (T-ALL), high IGFBP7 expression predicts primary therapy resistance. In order to elucidat …
DNA methylation of AMHRII and INSR gene is associated with the pathogenesis of Polycystic Ovary Syndrome (PCOS).
Zhong X, Jin F, Huang C, Du M, Gao M, Wei X. Zhong X, et al. Technol Health Care. 2021;29(S1):11-25. doi: 10.3233/THC-218002. Technol Health Care. 2021. PMID: 33682741 Free PMC article.
Insulin resistance is another important pathophysiological feature of PCOS. Although the expression of anti-mullerian hormone receptor (AMHR) and insulin receptor (INSR) in PCOS have been previously reported, the DNA methylation of the genes hav …
Insulin resistance is another important pathophysiological feature of PCOS. Although the expression of anti-mullerian hormone …
Directing DNA methylation to inhibit gene expression.
Hoffman AR, Hu JF. Hoffman AR, et al. Cell Mol Neurobiol. 2006 Jul-Aug;26(4-6):425-38. doi: 10.1007/s10571-006-9057-5. Epub 2006 May 19. Cell Mol Neurobiol. 2006. PMID: 16710755 Review.
: 1. DNA methylation is a critical epigenetic modification that silences gene transcription, participates in X-chromosome inactivation in females, and regulates genomic imprinting. 2. We have devised a method to inhibit transcriptional initiation by co …
: 1. DNA methylation is a critical epigenetic modification that silences gene transcription, participates in X-chromoso …
957 results