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Integrating structure to protein-protein interaction networks that drive metastasis to brain and lung in breast cancer.
Engin HB, Guney E, Keskin O, Oliva B, Gursoy A. Engin HB, et al. PLoS One. 2013 Nov 22;8(11):e81035. doi: 10.1371/journal.pone.0081035. eCollection 2013. PLoS One. 2013. PMID: 24278371 Free PMC article.
We have built the phenotype specific sub-networks of protein-protein interactions (PPIs) involving the relevant genes responsible for lung and brain metastasis from primary tumor in breast cancer. ...Functional analyses perf …
We have built the phenotype specific sub-networks of protein-protein interactions (PPIs) involving the relevant genes r …
An Integrated Systems Biology Approach Identifies TRIM25 as a Key Determinant of Breast Cancer Metastasis.
Walsh LA, Alvarez MJ, Sabio EY, Reyngold M, Makarov V, Mukherjee S, Lee KW, Desrichard A, Turcan Ş, Dalin MG, Rajasekhar VK, Chen S, Vahdat LT, Califano A, Chan TA. Walsh LA, et al. Cell Rep. 2017 Aug 15;20(7):1623-1640. doi: 10.1016/j.celrep.2017.07.052. Cell Rep. 2017. PMID: 28813674 Free PMC article.
At the root of most fatal malignancies are aberrantly activated transcriptional networks that drive metastatic dissemination. Although individual metastasis-associated genes have been described, the complex regulatory networks presiding over the initia …
At the root of most fatal malignancies are aberrantly activated transcriptional networks that drive metastatic dissemination. …