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2013 1
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2020 1
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2022 2
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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal.
Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO, Sun Y, Jacobsen A, Sinha R, Larsson E, Cerami E, Sander C, Schultz N. Gao J, et al. Sci Signal. 2013 Apr 2;6(269):pl1. doi: 10.1126/scisignal.2004088. Sci Signal. 2013. PMID: 23550210 Free PMC article.
The cBioPortal for Cancer Genomics (http://cbioportal.org) provides a Web resource for exploring, visualizing, and analyzing multidimensional cancer genomics data. ...Here, we provide a practical guide to the analysis and visualiza …
The cBioPortal for Cancer Genomics (http://cbioportal.org) provides a Web resource for exploring, visualizing, a …
Searching of Clinical Trials Made Easier in cBioPortal Using Patients' Genetic and Clinical Profiles.
Unberath P, Mahlmeister L, Reimer N, Busch H, Boerries M, Christoph J. Unberath P, et al. Appl Clin Inform. 2022 Mar;13(2):363-369. doi: 10.1055/s-0042-1743560. Epub 2022 Mar 30. Appl Clin Inform. 2022. PMID: 35354211 Free PMC article.
BACKGROUND: Molecular tumor boards (MTBs) cope with the complexity of an increased usage of genome sequencing data in cancer treatment. ...OBJECTIVES: In this study, a prototype for a search tool was developed to demonstrate how cBioPortal as a clin
BACKGROUND: Molecular tumor boards (MTBs) cope with the complexity of an increased usage of genome sequencing data in cance
Overexpression of TICRR and PPIF confer poor prognosis in endometrial cancer identified by gene co-expression network analysis.
Yang L, Cui Y, Sun X, Wang Y. Yang L, et al. Aging (Albany NY). 2021 Jan 20;13(3):4564-4589. doi: 10.18632/aging.202417. Epub 2021 Jan 20. Aging (Albany NY). 2021. PMID: 33495413 Free PMC article.
The incidence of endometrial cancer (EC) is intensively increasing. However, due to the complexity and heterogeneity of EC, the molecular targeted therapy is still limited. ...The copy number variations of candidate genes were investigated by cBioPortal. Enri …
The incidence of endometrial cancer (EC) is intensively increasing. However, due to the complexity and heterogeneity of EC, th …
Comprehensive Analysis of Expression and Prognostic Value of GATAs in Lung Cancer.
Gong C, Fan Y, Zhou X, Lai S, Wang L, Liu J. Gong C, et al. J Cancer. 2021 May 5;12(13):3862-3876. doi: 10.7150/jca.52623. eCollection 2021. J Cancer. 2021. PMID: 34093794 Free PMC article.
In the present study, the diverse expression patterns, prognostic values, genetic mutations, protein-protein interaction(PPI) networks of GATAs, Gene Ontology enrichment and Kyoto Encyclopedia of Genes and Genomes pathway in LC patients were analyzed using a serious of dat …
In the present study, the diverse expression patterns, prognostic values, genetic mutations, protein-protein interaction(PPI) networks of GA …
A simple in silico approach to generate gene-expression profiles from subsets of cancer genomics data.
Khurshed M, Molenaar RJ, van Noorden CJ. Khurshed M, et al. Biotechniques. 2019 Oct;67(4):172-176. doi: 10.2144/btn-2018-0179. Biotechniques. 2019. PMID: 31560238 Free article.
An overwhelming amount of cancer genomics data has become publicly available, and the complexity of these data makes it a challenge to perform in silico data exploration, integration and analysis, in particular for scientists lacking a backgroun …
An overwhelming amount of cancer genomics data has become publicly available, and the complexity of these data makes it …
PYCR in Kidney Renal Papillary Cell Carcinoma: Expression, Prognosis, Gene Regulation Network, and Regulation Targets.
Shao Z, Lu L, Cui Y, Deng L, Xu Q, Liang Q, Lu X, Zhang J, Chen J, Situ Y. Shao Z, et al. Front Biosci (Landmark Ed). 2022 Dec 28;27(12):336. doi: 10.31083/j.fbl2712336. Front Biosci (Landmark Ed). 2022. PMID: 36624948 Free article.
These genes play important roles in regulating the cell cycle and redox homeostasis as well as promoting growth signaling pathways. Proline is abnormally upregulated in a variety of cancers, and as the last key enzyme in proline production, PYCR plays an integral ro …
These genes play important roles in regulating the cell cycle and redox homeostasis as well as promoting growth signaling pathways. Proline …
Alzheimer Gene BIN1 may Simultaneously Influence Dementia Risk and Androgen Deprivation Therapy Dosage in Prostate Cancer.
Lehrer S, Rheinstein PH. Lehrer S, et al. Am J Clin Oncol. 2020 Oct;43(10):685-689. doi: 10.1097/COC.0000000000000727. Am J Clin Oncol. 2020. PMID: 32568785 Free PMC article.
METHODS: The authors examined the genomics of 492 prostate cancer cases in the Genomic Data Commons (GDC) TCGA Prostate Cancer (PRAD) data set. To access and analyze the data, 2 web-based interfaces were used: (1) the UCSC Xena browser, a web-based vis …
METHODS: The authors examined the genomics of 492 prostate cancer cases in the Genomic Data Commons (GDC) TCGA Prostate …