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Intensity-modulated proton therapy and osteoradionecrosis in oropharyngeal cancer.
Zhang W, Zhang X, Yang P, Blanchard P, Garden AS, Gunn B, Fuller CD, Chambers M, Hutcheson KA, Ye R, Lai SY, Radwan MAS, Zhu XR, Frank SJ. Zhang W, et al. Radiother Oncol. 2017 Jun;123(3):401-405. doi: 10.1016/j.radonc.2017.05.006. Epub 2017 May 23. Radiother Oncol. 2017. PMID: 28549794 Free PMC article.
PURPOSE: We compared mandibular doses and osteoradionecrosis in patients with oropharyngeal cancer after intensity-modulated radiation therapy (IMRT) or intensity-modulated proton therapy (IMPT). ...Use of IMPT …
PURPOSE: We compared mandibular doses and osteoradionecrosis in patients with oropharyngeal cancer after intensity …
Osteoradionecrosis After Intensity-Modulated Radiation Therapy or Proton Therapy in Oropharyngeal Carcinoma.
Yang F, Dee EC, Singh A, Wu Y, Suggitt JO, Treechairusame T, Silverio Polanco E, Honawar A, Zhang Z, Mah D, Sine K, Shim A, Lin H, Kang JJ, Tsai CJ, McBride SM, Riaz N, Gelblum DY, Zakeri K, Chen L, Shamseddine A, Yu Y, Huryn JM, Yom SK, Cracchiolo J, Ganly I, Cohen MA, Sherman EJ, Ho AL, Wong RJ, Estilo CL, Lee NY. Yang F, et al. JAMA Otolaryngol Head Neck Surg. 2026 Feb 1;152(2):135-143. doi: 10.1001/jamaoto.2025.4179. JAMA Otolaryngol Head Neck Surg. 2026. PMID: 41296362
While proton therapy offers superior dose conformality, its impact on ORN risk remains uncertain, particularly in patients with oropharyngeal squamous cell carcinoma (OPSCC). ...ORN rates were significantly higher after proton therapy compared w …
While proton therapy offers superior dose conformality, its impact on ORN risk remains uncertain, particularly in patients wit …
Proton Therapy for HPV-Associated Oropharyngeal Cancers of the Head and Neck: a De-Intensification Strategy.
Taku N, Wang L, Garden AS, Rosenthal DI, Gunn GB, Morrison WH, Fuller CD, Phan J, Reddy JP, Moreno AC, Spiotto MT, Chronowski G, Shah SJ, Mayo LL, Gross ND, Ferrarotto R, Zhu XR, Zhang X, Frank SJ. Taku N, et al. Curr Treat Options Oncol. 2021 Jun 4;22(6):54. doi: 10.1007/s11864-021-00847-y. Curr Treat Options Oncol. 2021. PMID: 34086150 Free PMC article. Review.
Intensity-modulated proton therapy (IMPT) is a form of radiotherapy that de-intensifies treatment through dose de-escalation to normal tissues without compromising dose to the primary tumor and involved, regional lymph nodes. ...Two phase III trials cu …
Intensity-modulated proton therapy (IMPT) is a form of radiotherapy that de-intensifies treatment through dose d …