Interaction network containing conserved and essential protein complexes in Escherichia coli.
Nature. 2005.
PMID: 15690043
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Interaction network containing conserved and essential protein complexes in Escherichia coli.
Nature. 2005 Feb 3;433(7025):531-7. doi: 10.1038/nature03239.
Nature. 2005.
PMID: 15690043
Proteins often function as components of multi-subunit complexes. Despite its long history as a model organism, no large-scale analysis of protein complexes in Escherichia coli has yet been reported. ...An interaction network …
Proteins often function as components of multi-subunit complexes. Despite its long history as a model organism, no large-scale …
The topology of the bacterial co-conserved protein network and its implications for predicting protein function.
BMC Genomics. 2008 Jun 30;9:313. doi: 10.1186/1471-2164-9-313.
BMC Genomics. 2008.
PMID: 18590549
Free PMC article.
BACKGROUND: Protein-protein interactions networks are most often generated from physical protein-protein interaction data. ...Since the topology of bacteria co-conservation protein-protein interaction …
BACKGROUND: Protein-protein interactions networks are most often generated from physical protein-prote …
Refinement of the subunit interaction network within the nucleosome remodelling and deacetylase (NuRD) complex.
FEBS J. 2017 Dec;284(24):4216-4232. doi: 10.1111/febs.14301. Epub 2017 Nov 13.
FEBS J. 2017.
PMID: 29063705
Free PMC article.
The complex comprises at least six proteins with two or more paralogues of each protein routinely identified when the complex is purified from cell extracts. ...First, the expression of many NuRD subunits in bacteria is unlikely to lead to folded, acti …
The complex comprises at least six proteins with two or more paralogues of each protein routinely identified when the …
Iteration method for predicting essential proteins based on orthology and protein-protein interaction networks.
BMC Syst Biol. 2012 Jul 18;6:87. doi: 10.1186/1752-0509-6-87.
BMC Syst Biol. 2012.
PMID: 22808943
Free PMC article.
Many computational methods have been proposed for predicting essential proteins by using the topological features of protein-protein interaction (PPI) networks. ...However, none of their methods has widely been acknowledged. RESULTS: By c …
Many computational methods have been proposed for predicting essential proteins by using the topological features of protei …
Characterization of the Deep-Sea Streptomyces sp. SCSIO 02999 Derived VapC/VapB Toxin-Antitoxin System in Escherichia coli.
Toxins (Basel). 2016 Jul 1;8(7):195. doi: 10.3390/toxins8070195.
Toxins (Basel). 2016.
PMID: 27376329
Free PMC article.
Overproduction of VapC strongly inhibited cell growth and resulted in a bleb-containing morphology in E. coli. The toxicity of VapC was neutralized through direct protein-protein interaction by a small protein antitoxin VapB encoded by a …
Overproduction of VapC strongly inhibited cell growth and resulted in a bleb-containing morphology in E. coli. The toxicity of …
Hybrid Fo complexes of the ATP synthases of spinach chloroplasts and Escherichia coli. Immunoprecipitation and mutant analyses.
Eur J Biochem. 1994 Nov 1;225(3):1221-8. doi: 10.1111/j.1432-1033.1994.1221b.x.
Eur J Biochem. 1994.
PMID: 7957212
Free article.
Hybrid Fo complexes of the ATP synthases of spinach chloroplast (CFo) and Escherichia coli (EFo) were investigated. ...The results suggested that a network of interactions between the subunits essential for proton translocation and/or cou …
Hybrid Fo complexes of the ATP synthases of spinach chloroplast (CFo) and Escherichia coli (EFo) were investigated. ... …
The activity and specificity of the outer membrane protein chaperone SurA are modulated by a proline isomerase domain.
mBio. 2013 Aug 13;4(4):e00540-13. doi: 10.1128/mBio.00540-13.
mBio. 2013.
PMID: 23943764
Free PMC article.
SurA is a component of the periplasmic chaperone network that plays a central role in biogenesis of integral outer membrane beta-barrel proteins (OMPs) in Escherichia coli. ...These mutations apparently bypass the requirement for a stable interactio …
SurA is a component of the periplasmic chaperone network that plays a central role in biogenesis of integral outer membrane beta-barr …
The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network.
FEBS J. 2017 Apr;284(7):1082-1095. doi: 10.1111/febs.14041. Epub 2017 Mar 16.
FEBS J. 2017.
PMID: 28207202
Free article.
Tripartite motif-containing protein 24 (TRIM24) is closely correlated with multiple cancers, and a recent study demonstrated that the bromodomain of TRIM24 is essential for the proliferation of lethal castration-resistant prostate cancer. Here, we identify th …
Tripartite motif-containing protein 24 (TRIM24) is closely correlated with multiple cancers, and a recent study demonstrated t …
Crystal structures of E. coli CcmG and its mutants reveal key roles of the N-terminal beta-sheet and the fingerprint region.
Proteins. 2006 Dec 1;65(4):1021-31. doi: 10.1002/prot.21184.
Proteins. 2006.
PMID: 17019698
Here we report the crystal structures of Escherichia coli CcmG and its two mutants, P144A and the N-terminal fifty seven-residue deletion mutant, and two additional deletion mutants were studied by circular dichroism. ...Structural comparison of E. coli CcmG …
Here we report the crystal structures of Escherichia coli CcmG and its two mutants, P144A and the N-terminal fifty seven-resid …
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