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The bacterial fimbrial tip acts as a mechanical force sensor.
Aprikian P, Interlandi G, Kidd BA, Le Trong I, Tchesnokova V, Yakovenko O, Whitfield MJ, Bullitt E, Stenkamp RE, Thomas WE, Sokurenko EV. Aprikian P, et al. Among authors: interlandi g. PLoS Biol. 2011 May;9(5):e1000617. doi: 10.1371/journal.pbio.1000617. Epub 2011 May 10. PLoS Biol. 2011. PMID: 21572990 Free PMC article.
Allosteric coupling in the bacterial adhesive protein FimH.
Rodriguez VB, Kidd BA, Interlandi G, Tchesnokova V, Sokurenko EV, Thomas WE. Rodriguez VB, et al. Among authors: interlandi g. J Biol Chem. 2013 Aug 16;288(33):24128-39. doi: 10.1074/jbc.M113.461376. Epub 2013 Jul 2. J Biol Chem. 2013. PMID: 23821547 Free PMC article.
Inhibition and Reversal of Microbial Attachment by an Antibody with Parasteric Activity against the FimH Adhesin of Uropathogenic E. coli.
Kisiela DI, Avagyan H, Friend D, Jalan A, Gupta S, Interlandi G, Liu Y, Tchesnokova V, Rodriguez VB, Sumida JP, Strong RK, Wu XR, Thomas WE, Sokurenko EV. Kisiela DI, et al. Among authors: interlandi g. PLoS Pathog. 2015 May 14;11(5):e1004857. doi: 10.1371/journal.ppat.1004857. eCollection 2015 May. PLoS Pathog. 2015. PMID: 25974133 Free PMC article.
Toggle switch residues control allosteric transitions in bacterial adhesins by participating in a concerted repacking of the protein core.
Kisiela DI, Magala P, Interlandi G, Carlucci LA, Ramos A, Tchesnokova V, Basanta B, Yarov-Yarovoy V, Avagyan H, Hovhannisyan A, Thomas WE, Stenkamp RE, Klevit RE, Sokurenko EV. Kisiela DI, et al. Among authors: interlandi g. PLoS Pathog. 2021 Apr 7;17(4):e1009440. doi: 10.1371/journal.ppat.1009440. eCollection 2021 Apr. PLoS Pathog. 2021. PMID: 33826682 Free PMC article.
35 results