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Intracytoplasmic sperm injection (ICSI) in extreme cases of male infertility.
Palermo GD, Neri QV, Schlegel PN, Rosenwaks Z. Palermo GD, et al. PLoS One. 2014 Dec 1;9(12):e113671. doi: 10.1371/journal.pone.0113671. eCollection 2014. PLoS One. 2014. PMID: 25437298 Free PMC article.
PATIENTS AND METHODS: In a retrospective cohort study carried out in an academic institution, intracytoplasmic sperm injection (ICSI) outcomes were reviewed as a function of length of microscopic sperm search in ejaculated and surgically retriev …
PATIENTS AND METHODS: In a retrospective cohort study carried out in an academic institution, intracytoplasmic sperm inject
Not every sperm is sacred; a perspective on male infertility.
Aitken RJ. Aitken RJ. Mol Hum Reprod. 2018 Jun 1;24(6):287-298. doi: 10.1093/molehr/gay010. Mol Hum Reprod. 2018. PMID: 29546342 Review.
This article is a personal perspective on male infertility, a condition that is not only extremely prevalent but also a major reason for couples to resort to ART. The introduction of ICSI as a form of facilitated fertilization had a revolutionary impac …
This article is a personal perspective on male infertility, a condition that is not only extremely prevalent but also a …
Treatment of infertility in men with spinal cord injury.
Brackett NL, Lynne CM, Ibrahim E, Ohl DA, Sønksen J. Brackett NL, et al. Nat Rev Urol. 2010 Mar;7(3):162-72. doi: 10.1038/nrurol.2010.7. Epub 2010 Feb 16. Nat Rev Urol. 2010. PMID: 20157304 Review.
The efficacy of intrauterine insemination increases as the total motile sperm count inseminated increases. In vitro fertilization and intracytoplasmic sperm injection are options in cases of extremely low total motile sperm count. …
The efficacy of intrauterine insemination increases as the total motile sperm count inseminated increases. In vitro fertilization and …
Updates on sperm retrieval techniques.
Leung A, Mira J, Hsiao W. Leung A, et al. Transl Androl Urol. 2014 Mar;3(1):94-101. doi: 10.3978/j.issn.2223-4683.2014.02.03. Transl Androl Urol. 2014. PMID: 26816757 Free PMC article. Review.
In the most extreme form of male infertility, the male partner is azoospermic. The advent of in vitro fertilization (IVF)-intracytoplasmic sperm injection (ICSI) has revolutionized our ability to treat azoospermia in both ob …
In the most extreme form of male infertility, the male partner is azoospermic. The advent of in vitro fertilizat …
What to do when ICSI fails.
Maggiulli R, Neri QV, Monahan D, Hu J, Takeuchi T, Rosenwaks Z, Palermo GD. Maggiulli R, et al. Syst Biol Reprod Med. 2010 Oct;56(5):376-87. doi: 10.3109/19396361003770321. Syst Biol Reprod Med. 2010. PMID: 20849223 Review.
The refinement of gamete micromanipulation techniques has made conception possible for couples with male factor infertility who otherwise would remain childless. Moreover, intracytoplasmic sperm injection (ICSI) has ensured that such refr …
The refinement of gamete micromanipulation techniques has made conception possible for couples with male factor infertility wh …
In vitro fertilization for male infertility: when and how?
Hall J, Fishel S. Hall J, et al. Baillieres Clin Obstet Gynaecol. 1997 Dec;11(4):711-24. doi: 10.1016/s0950-3552(97)80008-9. Baillieres Clin Obstet Gynaecol. 1997. PMID: 9692012 Review.
The recent advent of micromanipulation and, in particular, intracytoplasmic sperm injection (ICSI) has overshadowed the use of these modified IVF procedures. ...IVF has much recent history in animal and also human work. Although ICSI is the most …
The recent advent of micromanipulation and, in particular, intracytoplasmic sperm injection (ICSI) has overshado …
Homozygous deleterious variants in MYCBPAP induce asthenoteratozoospermia involving abnormal acrosome biogenesis, manchette structure and sperm tail assembly in humans and mice.
Zhou Y, Tu C, Coutton C, Tang J, Tian S, Tang S, Martinez G, Zhou D, Tebbakh C, Wang J, Zouari R, Zhou X, Ben Mustapha SF, Wang X, Wu B, Geng X, Liu S, Jin L, Shi H, Tan YQ, Ray PF, Wang L, Yang X, Zhang F, Liu C. Zhou Y, et al. Sci China Life Sci. 2025 Mar;68(3):777-792. doi: 10.1007/s11427-024-2757-7. Epub 2024 Dec 18. Sci China Life Sci. 2025. PMID: 39704931
Subsequently, we generated a Mycbpap knockout (Mycbpap(-/-)) mouse model, which also exhibited male infertility with reduced sperm motility and abnormal morphologies in sperm heads and flagella. ...Furthermore, MYCBPAP-associated male inferti
Subsequently, we generated a Mycbpap knockout (Mycbpap(-/-)) mouse model, which also exhibited male infertility with reduced …
Comparison of the fertilization rate after intracytoplasmic sperm injection (ICSI) using ejaculated sperms, epididymal sperms and testicular sperms.
Sukcharoen N, Sithipravej T, Promviengchai S, Chinpilas V, Boonkasemsanti W. Sukcharoen N, et al. J Med Assoc Thai. 1998 Aug;81(8):565-71. J Med Assoc Thai. 1998. PMID: 9737108
Intracytoplasmic sperm injection (ICSI) has been successfully used to achieve fertilization and pregnancies for patients with extreme oligoastheno-zoospermia using ejaculated sperms or patients with azoospermia using epididymal or testicular spe
Intracytoplasmic sperm injection (ICSI) has been successfully used to achieve fertilization and pregnancies for
Fertilizing capacity of epididymal and testicular sperm using intracytoplasmic sperm injection (ICSI).
Silber SJ, Devroey P, Tournaye H, Van Steirteghem AC. Silber SJ, et al. Reprod Fertil Dev. 1995;7(2):281-92; discussion 292-3. doi: 10.1071/rd9950281. Reprod Fertil Dev. 1995. PMID: 7480847 Clinical Trial.
However, the results to date have been poor, and although a minority of patients achieved good fertilization rates with IVF, the vast majority (81%) had consistently poor or no fertilization and the pregnancy rate averaged only 9%. Recently, intracytoplasmic sperm
However, the results to date have been poor, and although a minority of patients achieved good fertilization rates with IVF, the vast majori …
Failure of fertilization following intracytoplasmic injection of round-headed sperm.
Khalili MA, Kalantar SM, Vahidi S, Ghafour-Zadeh M. Khalili MA, et al. Ann Saudi Med. 1998;18(5):408-11. doi: 10.5144/0256-4947.1998.408. Ann Saudi Med. 1998. PMID: 17344712 Free article.
BACKGROUND: Intracytoplasmic sperm injection (ICSI) is a very effective technique for the treatment of male factor infertility, even in severe cases. ...CONCLUSION: The results clearly demonstrate the important role of normal head …
BACKGROUND: Intracytoplasmic sperm injection (ICSI) is a very effective technique for the treatment of male
34 results