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198 results

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Page 1
Intranasal or transdermal nicotine for the treatment of postoperative pain.
Matthews AM, Fu R, Dana T, Chou R. Matthews AM, et al. Cochrane Database Syst Rev. 2016 Jan 12;2016(1):CD009634. doi: 10.1002/14651858.CD009634.pub2. Cochrane Database Syst Rev. 2016. PMID: 26756459 Free PMC article. Review.
OBJECTIVES: To assess the effect of transdermal or intranasal nicotine administration on postoperative pain, opioid analgesic use, and opioid-related adverse events. ...More research is needed to determine the effectiveness of nicotine for postoperative pain …
OBJECTIVES: To assess the effect of transdermal or intranasal nicotine administration on postoperative pain, opioid analgesic …
Nicotine replacement therapy versus control for smoking cessation.
Hartmann-Boyce J, Chepkin SC, Ye W, Bullen C, Lancaster T. Hartmann-Boyce J, et al. Cochrane Database Syst Rev. 2018 May 31;5(5):CD000146. doi: 10.1002/14651858.CD000146.pub5. Cochrane Database Syst Rev. 2018. PMID: 29852054 Free PMC article. Review.
BACKGROUND: Nicotine replacement therapy (NRT) aims to temporarily replace much of the nicotine from cigarettes to reduce motivation to smoke and nicotine withdrawal symptoms, thus easing the transition from cigarette smoking to complete abstinence. OBJECTIVE …
BACKGROUND: Nicotine replacement therapy (NRT) aims to temporarily replace much of the nicotine from cigarettes to reduce moti …
Nicotine replacement therapy.
Fant RV, Owen LL, Henningfield JE. Fant RV, et al. Prim Care. 1999 Sep;26(3):633-52. doi: 10.1016/s0095-4543(05)70121-4. Prim Care. 1999. PMID: 10436291 Review.
Physicians can help their patients quit smoking by recommending to all of their patients that they quit smoking with the help of nicotine replacement medications. Currently available forms of nicotine medications include gum, patch, nasal spray, and vapor inhaler. …
Physicians can help their patients quit smoking by recommending to all of their patients that they quit smoking with the help of nicotine
Intranasal delivery of a nicotine vaccine candidate induces antibodies in mouse blood and lung mucosal secretions that specifically neutralize nicotine.
Alzhrani RF, Xu H, Valdes SA, Cui Z. Alzhrani RF, et al. Drug Dev Ind Pharm. 2020 Oct;46(10):1656-1664. doi: 10.1080/03639045.2020.1820033. Epub 2020 Sep 15. Drug Dev Ind Pharm. 2020. PMID: 32892651
SIGNIFICANCE: The importance of this study is to establish the feasibility of inducing nicotine-neutralizing antibodies not only in the blood, but also in the lung and nasal mucosal secretions, by intranasal administration of a nicotine vaccine candidate. ... …
SIGNIFICANCE: The importance of this study is to establish the feasibility of inducing nicotine-neutralizing antibodies not only in t …
Intranasal nicotine increases postoperative nausea and is ineffective in reducing pain following laparoscopic bariatric surgery in tobacco-Naive females: a randomized, double blind trial.
Weingarten TN, McGlinch BP, Liedl L, Kendrick ML, Kellogg TA, Schroeder DR, Sprung J. Weingarten TN, et al. Obes Surg. 2015 Mar;25(3):506-13. doi: 10.1007/s11695-014-1431-7. Obes Surg. 2015. PMID: 25190522 Clinical Trial.
BACKGROUND: Nicotine is a known analgesic. Our primary aim was to test the hypothesis that intranasal nicotine administered intraoperatively reduces the need for postoperative opioids. ...CONCLUSION: Intraoperative intranasal nicotine did not ex …
BACKGROUND: Nicotine is a known analgesic. Our primary aim was to test the hypothesis that intranasal nicotine administ …
Intranasal mesenchymal stem cell secretome administration markedly inhibits alcohol and nicotine self-administration and blocks relapse-intake: mechanism and translational options.
Quintanilla ME, Ezquer F, Morales P, Santapau D, Berríos-Cárcamo P, Ezquer M, Herrera-Marschitz M, Israel Y. Quintanilla ME, et al. Stem Cell Res Ther. 2019 Jul 8;10(1):205. doi: 10.1186/s13287-019-1304-z. Stem Cell Res Ther. 2019. PMID: 31286996 Free PMC article.
METHODS: Rats bred for their alcohol preference ingested alcohol chronically or were trained to self-administer nicotine. Secretome of human adipose tissue-derived activated mesenchymal stem cells was administered intranasally to animals, both (i) chronically consum …
METHODS: Rats bred for their alcohol preference ingested alcohol chronically or were trained to self-administer nicotine. Secretome o …
Intranasal nicotine for postoperative pain treatment.
Flood P, Daniel D. Flood P, et al. Anesthesiology. 2004 Dec;101(6):1417-21. doi: 10.1097/00000542-200412000-00023. Anesthesiology. 2004. PMID: 15564950 Free article. Clinical Trial.
BACKGROUND: Despite pharmacological treatment, 70-80% of patients report moderate to severe pain after surgery. Because nicotine has been reported to have analgesic properties in animal and human volunteer studies, the authors assessed the analgesic efficacy of a single 3 …
BACKGROUND: Despite pharmacological treatment, 70-80% of patients report moderate to severe pain after surgery. Because nicotine has …
Subjective response to intranasal nicotine administration in oral contraceptive users and naturally-cycling women.
Allen AM, Friedrichsen SC, Petersen N, Allen SS. Allen AM, et al. Addict Behav. 2019 Nov;98:106043. doi: 10.1016/j.addbeh.2019.106043. Epub 2019 Jul 3. Addict Behav. 2019. PMID: 31310925 Free PMC article.
Each lab session included self-administration of intranasal nicotine (Time 0 min), assessment of subjective response via the Subjective State Scale (-30 and + 5 min). ...During ad libitum smoking, the OC group had significantly lower craving after nicotine ad …
Each lab session included self-administration of intranasal nicotine (Time 0 min), assessment of subjective response via the S …
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study.
Cheng W, Parker N, Karadag N, Koch E, Hindley G, Icick R, Shadrin A, O'Connell KS, Bjella T, Bahrami S, Rahman Z, Tesfaye M, Jaholkowski P, Rødevand L, Holen B, Lagerberg TV, Steen NE, Djurovic S, Dale AM, Frei O, Smeland OB, Andreassen OA. Cheng W, et al. Lancet Psychiatry. 2023 Jun;10(6):441-451. doi: 10.1016/S2215-0366(23)00143-8. Lancet Psychiatry. 2023. PMID: 37208114 Free PMC article.
Enrichment of mapped genes implicated neuronal and olfactory cells as well as drug-gene targets for nicotine, alcohol, and duloxetine. Psychotic disorders showed a causal effect on cannabis phenotypes, and lifetime cannabis use had a causal effect on bipolar disorder. ...
Enrichment of mapped genes implicated neuronal and olfactory cells as well as drug-gene targets for nicotine, alcohol, and duloxetine …
Intranasal nicotine spray does not augment the adverse effects of cigarette smoking on myocardial oxygen demand or coronary arterial dimensions.
Keeley EC, Pirwitz MJ, Landau C, Lange RA, Hillis LD, Foerster EH, Conrad K, Willard JE. Keeley EC, et al. Am J Med. 1996 Oct;101(4):357-63. doi: 10.1016/s0002-9343(96)00237-9. Am J Med. 1996. PMID: 8873505 Clinical Trial.
This study was performed to assess the effects of cigarette smoking with and without concomitant intranasal nicotine spray on: (a) myocardial oxygen demand, (b) coronary arterial dimensions, and (c) the development of acute cardiovascular tolerance. ...Subsequently, …
This study was performed to assess the effects of cigarette smoking with and without concomitant intranasal nicotine spray on: …
198 results