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144 results

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Evidence-based complementary treatment of pancreatic cancer: a review of adjunct therapies including paricalcitol, hydroxychloroquine, intravenous vitamin C, statins, metformin, curcumin, and aspirin.
Bigelsen S. Bigelsen S. Cancer Manag Res. 2018 Jul 13;10:2003-2018. doi: 10.2147/CMAR.S161824. eCollection 2018. Cancer Manag Res. 2018. PMID: 30034255 Free PMC article. Review.
Hydroxychloroquine has been shown to inhibit autophagy, a process by which dying cells recycle injured organelles and internal toxins to generate needed energy for survival and reproduction. Intravenous vitamin C creates a toxic accumulation of hydrogen peroxide within …
Hydroxychloroquine has been shown to inhibit autophagy, a process by which dying cells recycle injured organelles and internal toxins to gen …
Utility of Intravenous Curcumin Nanodelivery Systems for Improving In Vivo Pharmacokinetics and Anticancer Pharmacodynamics.
Bagheri M, van Nostrum CF, Kok RJ, Storm G, Hennink WE, Heger M. Bagheri M, et al. Mol Pharm. 2022 Sep 5;19(9):3057-3074. doi: 10.1021/acs.molpharmaceut.2c00455. Epub 2022 Aug 16. Mol Pharm. 2022. PMID: 35973068 Free PMC article. Review.
Curcumin nanoformulations for intravenous injection have been developed to offset poor absorption, biotransformation, degradation, and excessive clearance associated with parenteral delivery. This review investigates (1) whether intravenous nanoformulations i …
Curcumin nanoformulations for intravenous injection have been developed to offset poor absorption, biotransformation, degradat …
Curcumin Administration Routes in Breast Cancer Treatment.
Mayo B, Penroz S, Torres K, Simón L. Mayo B, et al. Int J Mol Sci. 2024 Oct 26;25(21):11492. doi: 10.3390/ijms252111492. Int J Mol Sci. 2024. PMID: 39519045 Free PMC article. Review.
The intravenous administration of curcumin-loaded nanoparticles significantly improves bioavailability and therapeutic outcomes compared to oral routes. ...Advancing research on curcumin in breast cancer treatment is essential for improving therapeutic …
The intravenous administration of curcumin-loaded nanoparticles significantly improves bioavailability and therapeutic outcome …
Intravenous Nanocarrier for Improved Efficacy of Quercetin and Curcumin against Breast Cancer Cells: Development and Comparison of Single and Dual Drug-Loaded Formulations Using Hemolysis, Cytotoxicity and Cellular Uptake Studies.
Rahman MA, Mittal V, Wahab S, Alsayari A, Bin Muhsinah A, Almaghaslah D. Rahman MA, et al. Membranes (Basel). 2022 Jul 15;12(7):713. doi: 10.3390/membranes12070713. Membranes (Basel). 2022. PMID: 35877916 Free PMC article.
The present work highlights the suitability of an oil-based nanocarrier to deliver quercetin (Q) and curcumin (C) through the intravenous route for treatment of breast cancer. The nanoemulsion prepared by the modified emulsification-solvent evaporation method …
The present work highlights the suitability of an oil-based nanocarrier to deliver quercetin (Q) and curcumin (C) through the intr …
Anti-Cancer Properties of Two Intravenously Administrable Curcumin Formulations as Evaluated in the 3D Patient-Derived Cancer Spheroid Model.
Niederreiter M, Klein J, Schmitz SBM, Werner J, Mayer B. Niederreiter M, et al. Int J Mol Sci. 2024 Aug 5;25(15):8543. doi: 10.3390/ijms25158543. Int J Mol Sci. 2024. PMID: 39126111 Free PMC article.
Curcumin (Cur) is a heavily used complementary derived drug from cancer patients. Spheroid samples derived from 82 patients were prepared and treated after 48 h with two Cur formulations (CurA, CurB) in mono- and combination therapy. ...Cur formulations were more ef …
Curcumin (Cur) is a heavily used complementary derived drug from cancer patients. Spheroid samples derived from 82 patients we …
Curcumin-loaded biodegradable polymeric micelles for colon cancer therapy in vitro and in vivo.
Gou M, Men K, Shi H, Xiang M, Zhang J, Song J, Long J, Wan Y, Luo F, Zhao X, Qian Z. Gou M, et al. Nanoscale. 2011 Apr;3(4):1558-67. doi: 10.1039/c0nr00758g. Epub 2011 Jan 31. Nanoscale. 2011. PMID: 21283869
In an alginate-encapsulated cancer cell assay, intravenous application of Cur/MPEG-PCL micelles more efficiently inhibited the tumor cell-induced angiogenesis in vivo than that of free curcumin. ...In conclusion, Cur/MPEG-PCL micelles are an excellent intr …
In an alginate-encapsulated cancer cell assay, intravenous application of Cur/MPEG-PCL micelles more efficiently inhibited the …
Selective delivery of curcumin to breast cancer cells by self-targeting apoferritin nanocages with pH-responsive and low toxicity.
Ji P, Wang X, Yin J, Mou Y, Huang H, Ren Z. Ji P, et al. Drug Deliv. 2022 Dec;29(1):986-996. doi: 10.1080/10717544.2022.2056662. Drug Deliv. 2022. PMID: 35363115 Free PMC article.
Breast cancer is prevalent and diverse with significantly high incidence and mortality rates. Curcumin (Cur), a polyphenol component of turmeric, has been widely recognized as having strong anti-breast cancer activity. ...
Breast cancer is prevalent and diverse with significantly high incidence and mortality rates. Curcumin (Cur), a polyphenol com …
Pharmacokinetics of liposomal curcumin (Lipocurc) infusion: effect of co-medication in cancer patients and comparison with healthy individuals.
Bolger GT, Licollari A, Tan A, Greil R, Vcelar B, Greil-Ressler S, Weiss L, Schönlieb C, Magnes T, Radl B, Majeed M, Sordillo PP. Bolger GT, et al. Cancer Chemother Pharmacol. 2019 Feb;83(2):265-275. doi: 10.1007/s00280-018-3730-5. Epub 2018 Nov 14. Cancer Chemother Pharmacol. 2019. PMID: 30430227
PURPOSE: Investigation of the impact of co-medication on the plasma levels of curcumin and tetrahydrocurcumin (THC) in cancer patients and a comparison of the pharmacokinetics of curcumin and plasma levels of THC between cancer patients and healthy ind …
PURPOSE: Investigation of the impact of co-medication on the plasma levels of curcumin and tetrahydrocurcumin (THC) in cancer …
Redox nanoparticles inhibit curcumin oxidative degradation and enhance its therapeutic effect on prostate cancer.
Thangavel S, Yoshitomi T, Sakharkar MK, Nagasaki Y. Thangavel S, et al. J Control Release. 2015 Jul 10;209:110-9. doi: 10.1016/j.jconrel.2015.04.025. Epub 2015 Apr 22. J Control Release. 2015. PMID: 25912409
In this study, we were able to suppress curcumin's oxidative degradation by encapsulating it in a nanoparticle that also acts as a radical scavenger. ...These results demonstrated that RNP(N) is a promising drug carrier with unique ROS-scavenging abilities, and it i …
In this study, we were able to suppress curcumin's oxidative degradation by encapsulating it in a nanoparticle that also acts …
Curcumin loaded fibrinogen nanoparticles for cancer drug delivery.
Rejinold NS, Muthunarayanan M, Chennazhi KP, Nair SV, Jayakumar R. Rejinold NS, et al. J Biomed Nanotechnol. 2011 Aug;7(4):521-34. doi: 10.1166/jbn.2011.1320. J Biomed Nanotechnol. 2011. PMID: 21870456
In this work we prepared and evaluated the curcumin loaded fibrinogen nanoparticles (CRC-FNPs) as a novel drug delivery system for cancer therapy. ...The blood compatibility of CRC-FNPs throws light on the fact that it is possible to administer the prepared nanoform …
In this work we prepared and evaluated the curcumin loaded fibrinogen nanoparticles (CRC-FNPs) as a novel drug delivery system for …
144 results