Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1954 3
1960 1
1963 1
1966 1
1967 1
1968 1
1976 1
1977 1
1978 1
1979 1
1980 1
1981 1
1982 2
1984 1
1985 5
1987 3
1988 2
1989 1
1990 3
1991 2
1992 2
1995 4
1996 2
1998 11
1999 6
2000 9
2001 8
2002 14
2003 10
2004 10
2005 13
2006 16
2007 19
2008 22
2009 19
2010 31
2011 29
2012 33
2013 39
2014 38
2015 41
2016 37
2017 41
2018 36
2019 43
2020 46
2021 61
2022 61
2023 52
2024 55
2025 54

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

783 results

Results by year

Filters applied: . Clear all
Page 1
Bioactive sesquiterpenes from Inula helenium.
Zheng X, Wu Z, Xu J, Zhang X, Tu Y, Lei J, Yuan R, Cheng H, Wang Q, Yu J. Zheng X, et al. Bioorg Chem. 2021 Sep;114:105066. doi: 10.1016/j.bioorg.2021.105066. Epub 2021 Jun 6. Bioorg Chem. 2021. PMID: 34134031
Twenty-one eudesmane-type sesquiterpenes, including five new compounds, were isolated from the roots of Inula helenium. The structures of the new compounds (1-5) were determined by extensive spectroscopic data interpretation, single-crystal X-ray diffraction analysi …
Twenty-one eudesmane-type sesquiterpenes, including five new compounds, were isolated from the roots of Inula helenium. The st …
Inula helenium extract and lidocaine-loaded electrospun wound dressings for managing skin wounds pain and their healing: An in vitro and in vivo study.
Wang H, Li H, Zhao P, Zhang H, Jalili S. Wang H, et al. J Biomater Appl. 2024 Oct;39(4):367-376. doi: 10.1177/08853282241265920. Epub 2024 Jul 23. J Biomater Appl. 2024. PMID: 39042854
The skin injuries pose a substantial public health challenge, not only due to their physical trauma but also the accompanying pain and complexities in wound healing. In the current research, Inula helenium extract and lidocaine were loaded into electrospun PVA/calci …
The skin injuries pose a substantial public health challenge, not only due to their physical trauma but also the accompanying pain and compl …
Elecampane (Inula helenium) Root Extract and Its Major Sesquiterpene Lactone, Alantolactone, Inhibit Adipogenesis of 3T3-L1 Preadipocytes.
Jung YS, Jeong YJ, Kim JH, Jeon CH, Lee SO. Jung YS, et al. Molecules. 2022 Jul 25;27(15):4765. doi: 10.3390/molecules27154765. Molecules. 2022. PMID: 35897937 Free PMC article.
Recent studies have shown that Nur77 and AMPKalpha play an important role in regulating adipogenesis and isoalantolactone (ISO) dual-targeting AMPKalpha and Nur77 inhibits adipogenesis. In this study, we hypothesized that Inula helenium (elecampane) root extract (IH …
Recent studies have shown that Nur77 and AMPKalpha play an important role in regulating adipogenesis and isoalantolactone (ISO) dual-targeti …
Influence of Inula helenium rhizomes and Matricaria chamomilla inflorescences on the biochemical and physiological parameters in male rats fed a high-fat diet.
Lieshchova M, Yefimov V, Brygadyrenko V. Lieshchova M, et al. Rocz Panstw Zakl Hig. 2023;74(4):447-458. doi: 10.32394/rpzh.2023.0281. Rocz Panstw Zakl Hig. 2023. PMID: 38117160
RESULTS: In a laboratory experiment on male rats, it was found that the addition of dry crushed rhizomes of Inula helenium L. and inflorescences of Matricaria chamomilla L. to the diet caused opposite changes in body weight. ...The rhizomes of I. helenium cau …
RESULTS: In a laboratory experiment on male rats, it was found that the addition of dry crushed rhizomes of Inula helenium L. …
Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium.
Gierlikowska B, Gierlikowski W, Bekier K, Skalicka-Woźniak K, Czerwińska ME, Kiss AK. Gierlikowska B, et al. J Ethnopharmacol. 2020 Mar 1;249:112311. doi: 10.1016/j.jep.2019.112311. Epub 2019 Oct 20. J Ethnopharmacol. 2020. PMID: 31644941 Free article.
AIM OF THE STUDY: During a screening of plants traditionally used in respiratory tracts diseases (e.g. cough, rhinitis, bronchitis, throat infection, fever, influenza) in Europe, we have selected roots of Inula helenium and aerial parts of Grindelia squarrosa as a p …
AIM OF THE STUDY: During a screening of plants traditionally used in respiratory tracts diseases (e.g. cough, rhinitis, bronchitis, throat i …
Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells.
Yan YY, Zhang Q, Zhang B, Yang B, Lin NM. Yan YY, et al. Nat Prod Res. 2020 Sep;34(17):2539-2544. doi: 10.1080/14786419.2018.1543676. Epub 2019 Jan 19. Nat Prod Res. 2020. PMID: 30661396
Isoalantolactone is one of the major active ingredients from Inula helenium L. However, it is low cost-effective to isolate isoalantolactone from Inula helenium L. ...
Isoalantolactone is one of the major active ingredients from Inula helenium L. However, it is low cost-effective to isolate is …
Efficacy of methanol-water extract of Inula helenium root against oxidative DNA damage.
Nder AE. Nder AE. J Tradit Chin Med. 2021 Apr;41(2):293-300. J Tradit Chin Med. 2021. PMID: 33825410 Free article.
OBJECTIVE: To investigate the efficacy of methanol-water extract of Inula helenium root against oxidative DNA damage. METHODS: Antioxidant properties of methanol-water extract of Inula helenium root were revealed by 2,2'-azinobis (3-ethylbenzothiazolin …
OBJECTIVE: To investigate the efficacy of methanol-water extract of Inula helenium root against oxidative DNA damage. METHODS: …
The Sesquiterpene Lactone-Rich Fraction of Inula helenium L. Enhances the Antitumor Effect of Anti-PD-1 Antibody in Colorectal Cancer: Integrative Phytochemical, Transcriptomic, and Experimental Analyses.
Chun J, Park SM, Lee M, Ha IJ, Jeong MK. Chun J, et al. Cancers (Basel). 2023 Jan 20;15(3):653. doi: 10.3390/cancers15030653. Cancers (Basel). 2023. PMID: 36765611 Free PMC article.
We systemically analyzed gene expression profiles of cells in response to two major sesquiterpene lactones, alantolactone and isoalantolactone, and determined whether the sesquiterpene lactone-rich fraction of Inula helenium L. (SFIH) enhances the antitumor effect o …
We systemically analyzed gene expression profiles of cells in response to two major sesquiterpene lactones, alantolactone and isoalantolacto …
Biological Activities and Chemical Profile of Gentiana asclepiadea and Inula helenium Ethanolic Extracts.
Buza V, Niculae M, Hanganu D, Pall E, Burtescu RF, Olah NK, Matei-Lațiu MC, Vlasiuc I, Iozon I, Szakacs AR, Ielciu I, Ștefănuț LC. Buza V, et al. Molecules. 2022 May 31;27(11):3560. doi: 10.3390/molecules27113560. Molecules. 2022. PMID: 35684497 Free PMC article.
This study aimed to investigate the antioxidant, antimicrobial, and cytotoxic potential of ethanolic extracts obtained from Gentiana asclepiadea L. and Inula helenium L. roots, in relation to their chemical composition. The total polyphenols, flavonoids, and phenoli …
This study aimed to investigate the antioxidant, antimicrobial, and cytotoxic potential of ethanolic extracts obtained from Gentiana asclepi …
Sesquiterpenoids from the roots of Inula helenium inhibit acute myelogenous leukemia progenitor cells.
Ding Y, Pan W, Xu J, Wang T, Chen T, Liu Z, Xie C, Zhang Q. Ding Y, et al. Bioorg Chem. 2019 May;86:363-367. doi: 10.1016/j.bioorg.2019.01.055. Epub 2019 Jan 31. Bioorg Chem. 2019. PMID: 30753990
One new eudesmane sesquiterpenoid, 11beta-hydroxy-13-chloro-eudesm-5-en-12, 8-olide (1), was isolated from the roots of Inula helenium together with nine eudesmanolides (2-10) and one germacranolide (11). Their structures were elucidated on the basis of detailed spe …
One new eudesmane sesquiterpenoid, 11beta-hydroxy-13-chloro-eudesm-5-en-12, 8-olide (1), was isolated from the roots of Inula hele …
783 results