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409 results
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Validation of a novel molecular orbital approach (COMPACT) for the prospective safety evaluation of chemicals, by comparison with rodent carcinogenicity and Salmonella mutagenicity data evaluated by the U.S. NCI/NTP.
Lewis DF, Ioannides C, Parke DV. Lewis DF, et al. Among authors: ioannides c. Mutat Res. 1993 Feb;291(1):61-77. doi: 10.1016/0165-1161(93)90018-u. Mutat Res. 1993. PMID: 7678916
Induction of the rat hepatic microsomal mixed-function oxidases by two aza-arenes. A comparison with their non-heterocyclic analogues.
Ayrton AD, Trinick J, Wood BP, Smith JN, Ioannides C. Ayrton AD, et al. Among authors: ioannides c. Biochem Pharmacol. 1988 Dec 1;37(23):4565-71. doi: 10.1016/0006-2952(88)90673-9. Biochem Pharmacol. 1988. PMID: 3060123
A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism.
Ioannides C, Konsue N. Ioannides C, et al. Drug Metab Rev. 2015 Aug;47(3):356-73. doi: 10.3109/03602532.2015.1058819. Epub 2015 Jun 29. Drug Metab Rev. 2015. PMID: 26119477 Review.
Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices.
Ioannides C. Ioannides C. Xenobiotica. 2013 Jan;43(1):15-28. doi: 10.3109/00498254.2012.698766. Epub 2012 Jun 28. Xenobiotica. 2013. PMID: 22742738 Review.
Up-regulation of the CYP1 family in rat and human liver by the aliphatic isothiocyanates erucin and sulforaphane.
Hanlon N, Coldham N, Sauer MJ, Ioannides C. Hanlon N, et al. Among authors: ioannides c. Toxicology. 2008 Oct 30;252(1-3):92-8. doi: 10.1016/j.tox.2008.08.002. Epub 2008 Aug 19. Toxicology. 2008. PMID: 18773935
Differential response of human and rat epoxide hydrolase to polycyclic aromatic hydrocarbon exposure: studies using precision-cut tissue slices.
Pushparajah DS, Umachandran M, Plant KE, Plant N, Ioannides C. Pushparajah DS, et al. Among authors: ioannides c. Mutat Res. 2008 Apr 2;640(1-2):153-61. doi: 10.1016/j.mrfmmm.2008.01.004. Epub 2008 Feb 12. Mutat Res. 2008. PMID: 18336844
Effect of black tea intake on the excretion of mutagens in the urine of volunteers taking a beef meal.
Yoxall VR, Bishop J, Ioannides C. Yoxall VR, et al. Among authors: ioannides c. Cancer Epidemiol Biomarkers Prev. 2004 Dec;13(12):2196-202. Cancer Epidemiol Biomarkers Prev. 2004. PMID: 15598780 Clinical Trial.
Black tea intake modulates the excretion of urinary mutagens in rats exposed to 6-aminochrysene: induction of cytochromes P450 by 6-aminochrysene in the rat.
Yoxall V, Umachandran M, Wilson J, Kentish P, Ioannides C. Yoxall V, et al. Among authors: ioannides c. Mutagenesis. 2005 Jan;20(1):23-8. doi: 10.1093/mutage/gei002. Epub 2004 Dec 14. Mutagenesis. 2005. PMID: 15598702
Cytochromes P450 in the bioactivation of chemicals.
Ioannides C, Lewis DF. Ioannides C, et al. Curr Top Med Chem. 2004;4(16):1767-88. doi: 10.2174/1568026043387188. Curr Top Med Chem. 2004. PMID: 15579107 Review.
An improved method for the extraction of mutagens from human urine and cooked meat using blue rayon.
Yoxall V, Wilson J, Ioannides C. Yoxall V, et al. Among authors: ioannides c. Mutat Res. 2004 Apr 11;559(1-2):121-30. doi: 10.1016/j.mrgentox.2004.01.006. Mutat Res. 2004. PMID: 15066580
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