Ionescu R - Search Results

1

Vlasak J, Ionescu R. Vlasak J, et al. Among authors: ionescu r. MAbs. 2011 May-Jun;3(3):253-63. doi: 10.4161/mabs.3.3.15608. Epub 2011 May 1. MAbs. 2011. PMID: 21487244 Free PMC article. Review.

2

Kinetics of chemical degradation in monoclonal antibodies: relationship between rates at the molecular and peptide levels.

Ionescu R, Vlasak J. Ionescu R, et al. Anal Chem. 2010 Apr 15;82(8):3198-206. doi: 10.1021/ac902752e. Anal Chem. 2010. PMID: 20302349

3

Separation of post-translational modifications in monoclonal antibodies by exploiting subtle conformational changes under mildly acidic conditions.

Wang S, Ionescu R, Peekhaus N, Leung JY, Ha S, Vlasak J. Wang S, et al. Among authors: ionescu r. J Chromatogr A. 2010 Oct 15;1217(42):6496-502. doi: 10.1016/j.chroma.2010.08.044. Epub 2010 Aug 21. J Chromatogr A. 2010. PMID: 20828701

4

Impact of methionine oxidation in human IgG1 Fc on serum half-life of monoclonal antibodies.

Wang W, Vlasak J, Li Y, Pristatsky P, Fang Y, Pittman T, Roman J, Wang Y, Prueksaritanont T, Ionescu R. Wang W, et al. Among authors: ionescu r. Mol Immunol. 2011 Mar;48(6-7):860-6. doi: 10.1016/j.molimm.2010.12.009. Epub 2011 Jan 21. Mol Immunol. 2011. PMID: 21256596

5

Heterogeneity of monoclonal antibodies revealed by charge-sensitive methods.

Vlasak J, Ionescu R. Vlasak J, et al. Among authors: ionescu r. Curr Pharm Biotechnol. 2008 Dec;9(6):468-81. doi: 10.2174/138920108786786402. Curr Pharm Biotechnol. 2008. PMID: 19075686 Review.

6

Contribution of variable domains to the stability of humanized IgG1 monoclonal antibodies.

Ionescu RM, Vlasak J, Price C, Kirchmeier M. Ionescu RM, et al. J Pharm Sci. 2008 Apr;97(4):1414-26. doi: 10.1002/jps.21104. J Pharm Sci. 2008. PMID: 17721938

7

Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.

Vlasak J, Bussat MC, Wang S, Wagner-Rousset E, Schaefer M, Klinguer-Hamour C, Kirchmeier M, Corvaïa N, Ionescu R, Beck A. Vlasak J, et al. Among authors: ionescu r. Anal Biochem. 2009 Sep 15;392(2):145-54. doi: 10.1016/j.ab.2009.05.043. Epub 2009 Jun 2. Anal Biochem. 2009. PMID: 19497295

8

Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody.

Sinha S, Zhang L, Duan S, Williams TD, Vlasak J, Ionescu R, Topp EM. Sinha S, et al. Among authors: ionescu r. Protein Sci. 2009 Aug;18(8):1573-84. doi: 10.1002/pro.173. Protein Sci. 2009. PMID: 19544580 Free PMC article.

9

Evidence for trisulfide bonds in a recombinant variant of a human IgG2 monoclonal antibody.

Pristatsky P, Cohen SL, Krantz D, Acevedo J, Ionescu R, Vlasak J. Pristatsky P, et al. Among authors: ionescu r. Anal Chem. 2009 Aug 1;81(15):6148-55. doi: 10.1021/ac9006254. Anal Chem. 2009. PMID: 19591437

10

Pharmaceutical and immunological evaluation of human papillomavirus viruslike particle as an antigen carrier.

Ionescu RM, Przysiecki CT, Liang X, Garsky VM, Fan J, Wang B, Troutman R, Rippeon Y, Flanagan E, Shiver J, Shi L. Ionescu RM, et al. J Pharm Sci. 2006 Jan;95(1):70-9. doi: 10.1002/jps.20493. J Pharm Sci. 2006. PMID: 16315228

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