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154 results
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Identifying network of drug mode of action by gene expression profiling.
Iorio F, Tagliaferri R, di Bernardo D. Iorio F, et al. J Comput Biol. 2009 Feb;16(2):241-51. doi: 10.1089/cmb.2008.10TT. J Comput Biol. 2009. PMID: 19183001
Interactive data analysis and clustering of genomic data.
Ciaramella A, Cocozza S, Iorio F, Miele G, Napolitano F, Pinelli M, Raiconi G, Tagliaferri R. Ciaramella A, et al. Among authors: iorio f. Neural Netw. 2008 Mar-Apr;21(2-3):368-78. doi: 10.1016/j.neunet.2007.12.026. Epub 2007 Dec 31. Neural Netw. 2008. PMID: 18255261
A yeast synthetic network for in vivo assessment of reverse-engineering and modeling approaches.
Cantone I, Marucci L, Iorio F, Ricci MA, Belcastro V, Bansal M, Santini S, di Bernardo M, di Bernardo D, Cosma MP. Cantone I, et al. Among authors: iorio f. Cell. 2009 Apr 3;137(1):172-81. doi: 10.1016/j.cell.2009.01.055. Epub 2009 Mar 26. Cell. 2009. PMID: 19327819
NIRest: a tool for gene network and mode of action inference.
Lauria M, Iorio F, di Bernardo D. Lauria M, et al. Among authors: iorio f. Ann N Y Acad Sci. 2009 Mar;1158:257-64. doi: 10.1111/j.1749-6632.2008.03761.x. Ann N Y Acad Sci. 2009. PMID: 19348647
Discovery of drug mode of action and drug repositioning from transcriptional responses.
Iorio F, Bosotti R, Scacheri E, Belcastro V, Mithbaokar P, Ferriero R, Murino L, Tagliaferri R, Brunetti-Pierri N, Isacchi A, di Bernardo D. Iorio F, et al. Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14621-6. doi: 10.1073/pnas.1000138107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679242 Free PMC article.
Identification of small molecules enhancing autophagic function from drug network analysis.
Iorio F, Isacchi A, di Bernardo D, Brunetti-Pierri N. Iorio F, et al. Autophagy. 2010 Nov;6(8):1204-5. doi: 10.1073/pnas.1000138107. Epub 2010 Nov 16. Autophagy. 2010. PMID: 20930556
Transcriptional gene network inference from a massive dataset elucidates transcriptome organization and gene function.
Belcastro V, Siciliano V, Gregoretti F, Mithbaokar P, Dharmalingam G, Berlingieri S, Iorio F, Oliva G, Polishchuck R, Brunetti-Pierri N, di Bernardo D. Belcastro V, et al. Among authors: iorio f. Nucleic Acids Res. 2011 Nov 1;39(20):8677-88. doi: 10.1093/nar/gkr593. Epub 2011 Jul 23. Nucleic Acids Res. 2011. PMID: 21785136 Free PMC article.
Network based elucidation of drug response: from modulators to targets.
Iorio F, Saez-Rodriguez J, di Bernardo D. Iorio F, et al. BMC Syst Biol. 2013 Dec 13;7:139. doi: 10.1186/1752-0509-7-139. BMC Syst Biol. 2013. PMID: 24330611 Free PMC article. Review.
Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury.
Melas IN, Sakellaropoulos T, Iorio F, Alexopoulos LG, Loh WY, Lauffenburger DA, Saez-Rodriguez J, Bai JP. Melas IN, et al. Among authors: iorio f. Integr Biol (Camb). 2015 Aug;7(8):904-20. doi: 10.1039/c4ib00294f. Integr Biol (Camb). 2015. PMID: 25932872
A Semi-Supervised Approach for Refining Transcriptional Signatures of Drug Response and Repositioning Predictions.
Iorio F, Shrestha RL, Levin N, Boilot V, Garnett MJ, Saez-Rodriguez J, Draviam VM. Iorio F, et al. PLoS One. 2015 Oct 9;10(10):e0139446. doi: 10.1371/journal.pone.0139446. eCollection 2015. PLoS One. 2015. PMID: 26452147 Free PMC article.
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