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Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990-2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021.
GBD 2021 Adolescent BMI Collaborators. GBD 2021 Adolescent BMI Collaborators. Lancet. 2025 Mar 8;405(10481):785-812. doi: 10.1016/S0140-6736(25)00397-6. Epub 2025 Mar 3. Lancet. 2025. PMID: 40049185 Free PMC article.
METHODS: Using established methodology from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021, we modelled overweight and obesity across childhood and adolescence from 1990 to 2021, and then forecasted to 2050. ...At the super-region level in 2 …
METHODS: Using established methodology from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021, we modelled overwei …
The global, regional, and national burden of cancer, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023.
GBD 2023 Cancer Collaborators. GBD 2023 Cancer Collaborators. Lancet. 2025 Oct 11;406(10512):1565-1586. doi: 10.1016/S0140-6736(25)01635-6. Epub 2025 Sep 24. Lancet. 2025. PMID: 41015051 Free PMC article.
FINDINGS: In 2023, excluding non-melanoma skin cancers, there were 18.5 million (95% uncertainty interval 16.4 to 20.7) incident cases of cancer and 10.4 million (9.65 to 10.9) deaths, contributing to 271 million (255 to 285) DALYs globally. ...Between 2015 and 2030 …
FINDINGS: In 2023, excluding non-melanoma skin cancers, there were 18.5 million (95% uncertainty interval 16.4 to 20.7) incident cases of ca …
Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort.
Erlandson KM, Geng LN, Selvaggi CA, Thaweethai T, Chen P, Erdmann NB, Goldman JD, Henrich TJ, Hornig M, Karlson EW, Katz SD, Kim C, Cribbs SK, Laiyemo AO, Letts R, Lin JY, Marathe J, Parthasarathy S, Patterson TF, Taylor BD, Duffy ER, Haack M, Julg B, Maranga G, Hernandez C, Singer NG, Han J, Pemu P, Brim H, Ashktorab H, Charney AW, Wisnivesky J, Lin JJ, Chu HY, Go M, Singh U, Levitan EB, Goepfert PA, Nikolich JŽ, Hsu H, Peluso MJ, Kelly JD, Okumura MJ, Flaherman VJ, Quigley JG, Krishnan JA, Scholand MB, Hess R, Metz TD, Costantine MM, Rouse DJ, Taylor BS, Goldberg MP, Marshall GD, Wood J, Warren D, Horwitz L, Foulkes AS, McComsey GA; RECOVER-Adult Cohort. Erlandson KM, et al. Ann Intern Med. 2024 Sep;177(9):1209-1221. doi: 10.7326/M24-0737. Epub 2024 Aug 13. Ann Intern Med. 2024. PMID: 39133923 Free PMC article.
MEASUREMENTS: Participants completed questionnaires and standard clinical laboratory tests. RESULTS: Among 10 094 participants, 8746 had prior SARS-CoV-2 infection, 1348 were uninfected, 1880 had a PASC index of 12 or higher, and 3351 had a PASC index of zero. After propen …
MEASUREMENTS: Participants completed questionnaires and standard clinical laboratory tests. RESULTS: Among 10 094 participants, 8746 …
Burden of 375 diseases and injuries, risk-attributable burden of 88 risk factors, and healthy life expectancy in 204 countries and territories, including 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
GBD 2023 Disease and Injury and Risk Factor Collaborators. GBD 2023 Disease and Injury and Risk Factor Collaborators. Lancet. 2025 Oct 18;406(10513):1873-1922. doi: 10.1016/S0140-6736(25)01637-X. Epub 2025 Oct 12. Lancet. 2025. PMID: 41092926 Free PMC article.
Neonatal disorders and lower respiratory infections remained the leading level 3 CMNN causes globally in 2023, although both showed notable rate decreases from 2010, declining by 16.5% (10.6-22.0) and 24.8% (7.4-36.7), respectively. Injury-related age-standardised DALY rat …
Neonatal disorders and lower respiratory infections remained the leading level 3 CMNN causes globally in 2023, although both showed notable …
Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
GBD 2023 Causes of Death Collaborators. GBD 2023 Causes of Death Collaborators. Lancet. 2025 Oct 18;406(10513):1811-1872. doi: 10.1016/S0140-6736(25)01917-8. Epub 2025 Oct 12. Lancet. 2025. PMID: 41092928 Free PMC article.
FINDINGS: The initial years of the COVID-19 pandemic caused shifts in long-standing rankings of the leading causes of global deaths: it ranked as the number one age-standardised cause of death at Level 3 of the GBD cause classification hierarchy in 2021. By 2023, COVID-19 …
FINDINGS: The initial years of the COVID-19 pandemic caused shifts in long-standing rankings of the leading causes of global deaths: it rank …
Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950-2023: a demographic analysis for the Global Burden of Disease Study 2023.
GBD 2023 Demographics Collaborators. GBD 2023 Demographics Collaborators. Lancet. 2025 Oct 18;406(10513):1731-1810. doi: 10.1016/S0140-6736(25)01330-3. Epub 2025 Oct 12. Lancet. 2025. PMID: 41092927 Free PMC article.
We also identified higher than previously estimated mortality rates in sub-Saharan Africa for all sexes combined aged 5-14 years (87.3% higher in GBD 2023 than GBD 2021 on average across countries and territories over the 1950-2021 period) and for females aged 15-29 …
We also identified higher than previously estimated mortality rates in sub-Saharan Africa for all sexes combined aged 5-14 years (87.3% high …
ASCL2 reciprocally controls key trophoblast lineage decisions during hemochorial placenta development.
Varberg KM, Iqbal K, Muto M, Simon ME, Scott RL, Kozai K, Choudhury RH, Aplin JD, Biswell R, Gibson M, Okae H, Arima T, Vivian JL, Grundberg E, Soares MJ. Varberg KM, et al. Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2016517118. doi: 10.1073/pnas.2016517118. Proc Natl Acad Sci U S A. 2021. PMID: 33649217 Free PMC article.
In this study, we investigated invasive/extravillous trophoblast (EVT) cell differentiation using human trophoblast stem (TS) cells and a loss-of-function mutant Ascl2 rat model. ASCL2 transcripts are expressed in the EVT column and junctional zone, which represent tissue …
In this study, we investigated invasive/extravillous trophoblast (EVT) cell differentiation using human trophoblast stem (TS) cells a …
A Comprehensive Analysis of the Stability of Blood Eosinophil Levels.
Chipps BE, Jarjour N, Calhoun WJ, Iqbal A, Haselkorn T, Yang M, Brumm J, Corren J, Holweg CTJ, Bafadhel M. Chipps BE, et al. Ann Am Thorac Soc. 2021 Dec;18(12):1978-1987. doi: 10.1513/AnnalsATS.202010-1249OC. Ann Am Thorac Soc. 2021. PMID: 33891831 Free PMC article. Clinical Trial.
We examined 1) influence of intrinsic/extrinsic factors (comorbidities, medication, and patient history) using baseline data (n = 2,612); 2) monthly variation using placebo-treated patient data (n = 713); 3) stability of eosinophil classification (<150, 150-299, and 300 cel …
We examined 1) influence of intrinsic/extrinsic factors (comorbidities, medication, and patient history) using baseline data (n = 2,612); 2) …
Green Synthesis of CeO2 Nanoparticles from the Abelmoschus esculentus Extract: Evaluation of Antioxidant, Anticancer, Antibacterial, and Wound-Healing Activities.
Ahmed HE, Iqbal Y, Aziz MH, Atif M, Batool Z, Hanif A, Yaqub N, Farooq WA, Ahmad S, Fatehmulla A, Ahmad H. Ahmed HE, et al. Molecules. 2021 Jul 31;26(15):4659. doi: 10.3390/molecules26154659. Molecules. 2021. PMID: 34361812 Free PMC article.
The in vitro cytotoxicity of green synthesized CeO(2) was assessed against cervical cancerous cells (HeLa). The exposure of CeO(2) to HeLa cells at 10-125 g/mL caused a loss in cellular viability against cervical cancerous cells in a dose-dependent man …
The in vitro cytotoxicity of green synthesized CeO(2) was assessed against cervical cancerous cells (HeLa). The exposure of CeO(2) to …
Immune Response in Mice Immunized with Chimeric H1 Antigens.
Kotey EN, Ampofo WK, Daines R, Sadeyen JR, Iqbal M, Quaye O. Kotey EN, et al. Vaccines (Basel). 2021 Oct 15;9(10):1182. doi: 10.3390/vaccines9101182. Vaccines (Basel). 2021. PMID: 34696290 Free PMC article.
This study describes an approach that uses consensus sequence building to generate chimeric HAs (cHAs): two resultant H1 HA-based chimeras comprising of conserved sequences (within several areas spanning the head and stalk regions) of H1 and H5 or H9 HAs. These cHAs expressed in …
This study describes an approach that uses consensus sequence building to generate chimeric HAs (cHAs): two resultant H1 HA-based chimeras c …
58 results