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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1796 1
1807 2
1808 1
1809 1
1810 1
1814 1
1815 1
1821 2
1822 1
1823 5
1824 2
1825 2
1826 4
1827 2
1829 2
1830 2
1831 1
1832 3
1838 1
1840 1
1841 1
1842 5
1843 4
1845 1
1846 3
1847 1
1848 2
1849 2
1850 1
1851 2
1852 2
1854 1
1855 2
1856 3
1857 1
1858 1
1859 2
1860 3
1861 1
1862 3
1863 2
1864 1
1865 2
1866 4
1868 3
1869 5
1870 5
1871 2
1872 1
1873 2
1874 4
1875 11
1876 8
1877 3
1878 8
1879 6
1880 9
1881 7
1882 5
1883 5
1884 4
1885 3
1886 2
1887 7
1888 2
1889 4
1890 1
1891 4
1892 4
1893 7
1894 6
1895 2
1896 5
1897 8
1898 1
1899 2
1900 1
1902 1
1903 3
1904 1
1905 4
1906 2
1907 2
1908 3
1909 4
1910 1
1911 5
1912 4
1913 1
1914 2
1915 7
1916 2
1917 3
1918 1
1919 3
1920 5
1921 4
1922 4
1923 4
1924 10
1925 9
1926 7
1927 16
1928 10
1929 10
1930 10
1931 11
1932 22
1933 17
1934 15
1935 12
1936 16
1937 19
1938 9
1939 20
1940 12
1941 7
1942 13
1943 10
1944 10
1945 47
1946 112
1947 146
1948 137
1949 129
1950 180
1951 221
1952 307
1953 321
1954 298
1955 300
1956 307
1957 331
1958 358
1959 362
1960 366
1961 380
1962 467
1963 713
1964 1054
1965 745
1966 561
1967 586
1968 659
1969 669
1970 668
1971 666
1972 606
1973 607
1974 638
1975 1053
1976 1038
1977 1045
1978 1180
1979 1116
1980 1093
1981 1191
1982 1224
1983 1422
1984 1506
1985 1568
1986 1532
1987 1671
1988 1750
1989 2067
1990 2150
1991 2134
1992 2295
1993 2283
1994 2569
1995 2431
1996 2568
1997 2527
1998 2738
1999 2889
2000 3203
2001 3601
2002 4005
2003 4009
2004 4475
2005 4875
2006 5333
2007 5641
2008 6087
2009 6576
2010 6943
2011 7702
2012 8112
2013 8847
2014 9106
2015 9342
2016 9723
2017 10068
2018 10661
2019 11637
2020 13145
2021 14247
2022 14786
2023 2124
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Search Results

221,342 results
Results by year
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Page 1
Hepcidin-Ferroportin Interaction Controls Systemic Iron Homeostasis.
Nemeth E, Ganz T. Nemeth E, et al. Int J Mol Sci. 2021 Jun 17;22(12):6493. doi: 10.3390/ijms22126493. Int J Mol Sci. 2021. PMID: 34204327 Free PMC article. Review.
In vertebrates, the stability of iron concentration in plasma and extracellular fluid, and the total body iron content are maintained by the interaction of the iron-regulatory peptide hormone hepcidin with its receptor and cellular iron exporter ferrop …
In vertebrates, the stability of iron concentration in plasma and extracellular fluid, and the total body iron content are mai …
Iron and Cancer.
Torti SV, Manz DH, Paul BT, Blanchette-Farra N, Torti FM. Torti SV, et al. Annu Rev Nutr. 2018 Aug 21;38:97-125. doi: 10.1146/annurev-nutr-082117-051732. Annu Rev Nutr. 2018. PMID: 30130469 Free PMC article. Review.
Cancer cells exhibit an iron-seeking phenotype achieved through dysregulation of iron metabolic proteins. ...Uniquely, both iron excess and iron depletion can be utilized in anticancer therapies. ...
Cancer cells exhibit an iron-seeking phenotype achieved through dysregulation of iron metabolic proteins. ...Uniquely, both …
Current understanding of iron homeostasis.
Anderson GJ, Frazer DM. Anderson GJ, et al. Am J Clin Nutr. 2017 Dec;106(Suppl 6):1559S-1566S. doi: 10.3945/ajcn.117.155804. Epub 2017 Oct 25. Am J Clin Nutr. 2017. PMID: 29070551 Free PMC article. Review.
Cellular iron concentrations are modulated by the iron regulatory proteins (IRPs) IRP1 and IRP2. ...Too little or too much iron can have important clinical consequences. Most iron deficiency reflects an inadequate supply of iron in the diet, whe …
Cellular iron concentrations are modulated by the iron regulatory proteins (IRPs) IRP1 and IRP2. ...Too little or too much …
The Benefits and Risks of Iron Supplementation in Pregnancy and Childhood.
Georgieff MK, Krebs NF, Cusick SE. Georgieff MK, et al. Annu Rev Nutr. 2019 Aug 21;39:121-146. doi: 10.1146/annurev-nutr-082018-124213. Epub 2019 May 15. Annu Rev Nutr. 2019. PMID: 31091416 Free PMC article.
However, iron supplementation of iron-sufficient individuals is likely not necessary and may carry health risks for iron-sufficient and potentially some iron-deficient populations. This review considers the physiology of iron as a nutrient and h …
However, iron supplementation of iron-sufficient individuals is likely not necessary and may carry health risks for iron
Iron metabolism: pathophysiology and pharmacology.
Roemhild K, von Maltzahn F, Weiskirchen R, Knüchel R, von Stillfried S, Lammers T. Roemhild K, et al. Trends Pharmacol Sci. 2021 Aug;42(8):640-656. doi: 10.1016/j.tips.2021.05.001. Epub 2021 Jun 2. Trends Pharmacol Sci. 2021. PMID: 34090703 Free PMC article. Review.
Deregulated iron metabolism, which results in iron overload or iron deficiency, is observed in many different diseases. ...The role of iron in immunity and the connection between iron and cancer are also addressed. ...
Deregulated iron metabolism, which results in iron overload or iron deficiency, is observed in many different diseases. …
Iron metabolism and iron disorders revisited in the hepcidin era.
Camaschella C, Nai A, Silvestri L. Camaschella C, et al. Haematologica. 2020 Jan 31;105(2):260-272. doi: 10.3324/haematol.2019.232124. Print 2020. Haematologica. 2020. PMID: 31949017 Free PMC article. Review.
Iron regulatory proteins post-transcriptionally control genes encoding proteins that modulate iron uptake, recycling and storage and are themselves regulated by iron. The master regulator of systemic iron homeostasis is the liver peptide hepcidin, whic
Iron regulatory proteins post-transcriptionally control genes encoding proteins that modulate iron uptake, recycling and stora
Nutritional iron deficiency.
Zimmermann MB, Hurrell RF. Zimmermann MB, et al. Lancet. 2007 Aug 11;370(9586):511-20. doi: 10.1016/S0140-6736(07)61235-5. Lancet. 2007. PMID: 17693180 Review.
Nutritional iron deficiency arises when physiological requirements cannot be met by iron absorption from diet. ...Targeted iron supplementation, iron fortification of foods, or both, can control iron deficiency in populations. ...
Nutritional iron deficiency arises when physiological requirements cannot be met by iron absorption from diet. ...Targeted …
Iron deficiency: new insights into diagnosis and treatment.
Camaschella C. Camaschella C. Hematology Am Soc Hematol Educ Program. 2015;2015:8-13. doi: 10.1182/asheducation-2015.1.8. Hematology Am Soc Hematol Educ Program. 2015. PMID: 26637694 Review.
Iron deficiency and iron deficiency anemia are common conditions worldwide affecting especially children and young women. ...Oral iron salts correct absolute iron deficiency in most patients, because low hepcidin levels facilitate iron absorptio
Iron deficiency and iron deficiency anemia are common conditions worldwide affecting especially children and young women. ...O
Cellular Iron Metabolism and Regulation.
Gao G, Li J, Zhang Y, Chang YZ. Gao G, et al. Adv Exp Med Biol. 2019;1173:21-32. doi: 10.1007/978-981-13-9589-5_2. Adv Exp Med Biol. 2019. PMID: 31456203 Review.
Iron is an essential trace element in the human body, but excess iron is toxic as it contributes to oxidative damage. ...Balance of iron homeostasis depends on the expression levels and activities of iron carriers, iron transporters, and iron
Iron is an essential trace element in the human body, but excess iron is toxic as it contributes to oxidative damage. ...Balan
Regulation of the Iron Homeostatic Hormone Hepcidin.
Sangkhae V, Nemeth E. Sangkhae V, et al. Adv Nutr. 2017 Jan 17;8(1):126-136. doi: 10.3945/an.116.013961. Print 2017 Jan. Adv Nutr. 2017. PMID: 28096133 Free PMC article. Review.
Hepcidin also controls iron release from cells that recycle or store iron, thus regulating plasma iron concentrations. Hepcidin exerts its effects through its receptor, the cellular iron exporter ferroportin. Important regulators of hepcidin, and there …
Hepcidin also controls iron release from cells that recycle or store iron, thus regulating plasma iron concentrations. …
221,342 results
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