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A systems pharmacology model for inflammatory bowel disease.
Balbas-Martinez V, Ruiz-Cerdá L, Irurzun-Arana I, González-García I, Vermeulen A, Gómez-Mantilla JD, Trocóniz IF. Balbas-Martinez V, et al. PLoS One. 2018 Mar 7;13(3):e0192949. doi: 10.1371/journal.pone.0192949. eCollection 2018. PLoS One. 2018. PMID: 29513758 Free PMC article.
Beyond Deterministic Models in Drug Discovery and Development.
Irurzun-Arana I, Rackauckas C, McDonald TO, Trocóniz IF. Irurzun-Arana I, et al. Trends Pharmacol Sci. 2020 Nov;41(11):882-895. doi: 10.1016/ Epub 2020 Oct 5. Trends Pharmacol Sci. 2020. PMID: 33032836 Free PMC article. Review.
Semimechanistic models to relate noxious stimulation, movement, and pupillary dilation responses in the presence of opioids.
Marco-Ariño N, Vide S, Agustí M, Chen A, Jaramillo S, Irurzun-Arana I, Pacheco A, Gonzalez C, Jensen EW, Capsi-Morales P, Valencia JF, Troconiz IF, Gambus PL, Larson MD. Marco-Ariño N, et al. Among authors: irurzun arana i. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):581-593. doi: 10.1002/psp4.12729. Epub 2021 Nov 18. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 34716984 Free PMC article.
Phase I Study of Ceralasertib (AZD6738), a Novel DNA Damage Repair Agent, in Combination with Weekly Paclitaxel in Refractory Cancer.
Kim ST, Smith SA, Mortimer P, Loembé AB, Cho H, Kim KM, Smith C, Willis S, Irurzun-Arana I, Berges A, Hong JY, Park SH, Park JO, Park YS, Lim HY, Kang WK, Kozarewa I, Pierce AJ, Dean E, Lee J. Kim ST, et al. Among authors: irurzun arana i. Clin Cancer Res. 2021 Sep 1;27(17):4700-4709. doi: 10.1158/1078-0432.CCR-21-0251. Epub 2021 May 11. Clin Cancer Res. 2021. PMID: 33975862 Free PMC article. Clinical Trial.
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
Yap TA, Krebs MG, Postel-Vinay S, El-Khouiery A, Soria JC, Lopez J, Berges A, Cheung SYA, Irurzun-Arana I, Goldwin A, Felicetti B, Jones GN, Lau A, Frewer P, Pierce AJ, Clack G, Stephens C, Smith SA, Dean E, Hollingsworth SJ. Yap TA, et al. Among authors: irurzun arana i. Clin Cancer Res. 2021 Oct 1;27(19):5213-5224. doi: 10.1158/1078-0432.CCR-21-1032. Clin Cancer Res. 2021. PMID: 34301752 Free PMC article. Clinical Trial.
13 results