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211 results
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T cell killing does not require the formation of a stable mature immunological synapse.
Purbhoo MA, Irvine DJ, Huppa JB, Davis MM. Purbhoo MA, et al. Among authors: irvine dj. Nat Immunol. 2004 May;5(5):524-30. doi: 10.1038/ni1058. Epub 2004 Mar 28. Nat Immunol. 2004. PMID: 15048111
Direct observation of ligand recognition by T cells.
Irvine DJ, Purbhoo MA, Krogsgaard M, Davis MM. Irvine DJ, et al. Nature. 2002 Oct 24;419(6909):845-9. doi: 10.1038/nature01076. Nature. 2002. PMID: 12397360
Quantifying signaling-induced reorientation of T cell receptors during immunological synapse formation.
Moss WC, Irvine DJ, Davis MM, Krummel MF. Moss WC, et al. Among authors: irvine dj. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15024-9. doi: 10.1073/pnas.192573999. Epub 2002 Nov 1. Proc Natl Acad Sci U S A. 2002. PMID: 12415110 Free PMC article.
Dynamics of cell surface molecules during T cell recognition.
Davis MM, Krogsgaard M, Huppa JB, Sumen C, Purbhoo MA, Irvine DJ, Wu LC, Ehrlich L. Davis MM, et al. Among authors: irvine dj. Annu Rev Biochem. 2003;72:717-42. doi: 10.1146/annurev.biochem.72.121801.161625. Annu Rev Biochem. 2003. PMID: 14527326 Review.
CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse.
Li QJ, Dinner AR, Qi S, Irvine DJ, Huppa JB, Davis MM, Chakraborty AK. Li QJ, et al. Among authors: irvine dj. Nat Immunol. 2004 Aug;5(8):791-9. doi: 10.1038/ni1095. Epub 2004 Jul 11. Nat Immunol. 2004. PMID: 15247914
A role for the immunological synapse in lineage commitment of CD4 lymphocytes.
Maldonado RA, Irvine DJ, Schreiber R, Glimcher LH. Maldonado RA, et al. Among authors: irvine dj. Nature. 2004 Sep 30;431(7008):527-32. doi: 10.1038/nature02916. Epub 2004 Sep 22. Nature. 2004. PMID: 15386021
Immunological synapse arrays: patterned protein surfaces that modulate immunological synapse structure formation in T cells.
Doh J, Irvine DJ. Doh J, et al. Among authors: irvine dj. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5700-5. doi: 10.1073/pnas.0509404103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585528 Free PMC article.
Synthetic surfaces as artificial antigen presenting cells in the study of T cell receptor triggering and immunological synapse formation.
Irvine DJ, Doh J. Irvine DJ, et al. Semin Immunol. 2007 Aug;19(4):245-54. doi: 10.1016/j.smim.2007.02.011. Epub 2007 Mar 29. Semin Immunol. 2007. PMID: 17398113 Review.
Patterned surfaces as tools to study ligand recognition and synapse formation by T cells.
Irvine DJ, Doh J, Huang B. Irvine DJ, et al. Curr Opin Immunol. 2007 Aug;19(4):463-9. doi: 10.1016/j.coi.2007.05.003. Epub 2007 Jul 5. Curr Opin Immunol. 2007. PMID: 17616382 Review.
Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.
Maldonado RA, Soriano MA, Perdomo LC, Sigrist K, Irvine DJ, Decker T, Glimcher LH. Maldonado RA, et al. Among authors: irvine dj. J Exp Med. 2009 Apr 13;206(4):877-92. doi: 10.1084/jem.20082900. Epub 2009 Apr 6. J Exp Med. 2009. PMID: 19349465 Free PMC article.
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