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Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men.
Irwig MS. Irwig MS. Sex Med Rev. 2014 Jan;2(1):24-35. doi: 10.1002/smrj.19. Epub 2015 Oct 19. Sex Med Rev. 2014. PMID: 27784541 Review.
INTRODUCTION: Recent studies have reported persistent sexual and nonsexual adverse effects associated with the 5alpha-reductase inhibitor finasteride. AIMS: The first aim was to review the clinical studies of persistent sexual and nonsexual adverse effects associated with …
INTRODUCTION: Recent studies have reported persistent sexual and nonsexual adverse effects associated with the 5alpha-reductase inhibitor …
Finasteride and Suicide: A Postmarketing Case Series.
Irwig MS. Irwig MS. Dermatology. 2020;236(6):540-545. doi: 10.1159/000505151. Epub 2020 Jan 14. Dermatology. 2020. PMID: 31935720
BACKGROUND: In 2011, depression was added to the product labeling of finasteride in the USA. The US Food and Drug Administration's Adverse Event Reporting System database contains at least 36 death cases for finasteride. ...Apart from 1 case who had hyperlipidemia, …
BACKGROUND: In 2011, depression was added to the product labeling of finasteride in the USA. The US Food and Drug Administration's Ad …
Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia.
Irwig MS. Irwig MS. Curr Opin Endocrinol Diabetes Obes. 2015 Jun;22(3):248-53. doi: 10.1097/MED.0000000000000158. Curr Opin Endocrinol Diabetes Obes. 2015. PMID: 25871957 Review.
RECENT FINDINGS: Recent postmarketing reports and a US Food and Drug Administration analysis have documented uncommon persistent sexual and nonsexual side-effects in a subset of younger men who have taken finasteride 1 mg for androgenic alopecia. While the mechanisms of th …
RECENT FINDINGS: Recent postmarketing reports and a US Food and Drug Administration analysis have documented uncommon persistent sexual and …
Is there a role for 5α-reductase inhibitors in transgender individuals?
Irwig MS. Irwig MS. Andrology. 2021 Nov;9(6):1729-1731. doi: 10.1111/andr.12881. Epub 2020 Sep 2. Andrology. 2021. PMID: 32749751 Free article.
This commentary will explore the important clinical question regarding whether the antiandrogen class of 5alpha-reductase inhibitors should be considered as an effective and safe treatment option for transfeminine and/or transmasculine individuals. The use of finasteride i …
This commentary will explore the important clinical question regarding whether the antiandrogen class of 5alpha-reductase inhibitors should …
Beliefs and counseling practices among dermatologists regarding sexual and other adverse effects of finasteride.
Irwig MS, Sanz J, Lin D, Tan N, Dommasch E. Irwig MS, et al. Int J Impot Res. 2025 Jun;37(6):451-453. doi: 10.1038/s41443-023-00750-0. Epub 2023 Aug 4. Int J Impot Res. 2025. PMID: 37542152
Finasteride may cause low libido and erectile dysfunction and the product label of finasteride also includes post-marketing reactions of sexual dysfunction that continued after discontinuation of treatment, as well as male infertility and depression. ...This study i …
Finasteride may cause low libido and erectile dysfunction and the product label of finasteride also includes post-marketing re …
Persistent sexual side effects of finasteride: could they be permanent?
Irwig MS. Irwig MS. J Sex Med. 2012 Nov;9(11):2927-32. doi: 10.1111/j.1743-6109.2012.02846.x. Epub 2012 Jul 12. J Sex Med. 2012. PMID: 22789024
INTRODUCTION: Finasteride has been associated with sexual side effects that may persist despite discontinuation of the medication. ...AIM: To prospectively study whether the persistent sexual side effects associated with finasteride resolve or endure over time. METH …
INTRODUCTION: Finasteride has been associated with sexual side effects that may persist despite discontinuation of the medication. .. …
Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin.
Healy D, Bahrick A, Bak M, Barbato A, Calabrò RS, Chubak BM, Cosci F, Csoka AB, D'Avanzo B, Diviccaro S, Giatti S, Goldstein I, Graf H, Hellstrom WJG, Irwig MS, Jannini EA, Janssen PKC, Khera M, Kumar MT, Le Noury J, Lew-Starowicz M, Linden DEJ, Lüning C, Mangin D, Melcangi RC, Rodríguez OWMAAS, Panicker JN, Patacchini A, Pearlman AM, Pukall CF, Raj S, Reisman Y, Rubin RS, Schreiber R, Shipko S, Vašečková B, Waraich A. Healy D, et al. Among authors: irwig ms. Int J Risk Saf Med. 2022;33(1):65-76. doi: 10.3233/JRS-210023. Int J Risk Saf Med. 2022. PMID: 34719438 Free PMC article.
OBJECTIVE: To develop diagnostic criteria for post-SSRI sexual dysfunction (PSSD), persistent genital arousal disorder (PGAD) following serotonin reuptake inhibitors, post-finasteride syndrome (PFS) and post-retinoid sexual dysfunction (PRSD). METHODS: The original draft w …
OBJECTIVE: To develop diagnostic criteria for post-SSRI sexual dysfunction (PSSD), persistent genital arousal disorder (PGAD) following sero …
Persistent sexual side effects of finasteride for male pattern hair loss.
Irwig MS, Kolukula S. Irwig MS, et al. J Sex Med. 2011 Jun;8(6):1747-53. doi: 10.1111/j.1743-6109.2011.02255.x. Epub 2011 Mar 18. J Sex Med. 2011. PMID: 21418145
The mean number of sexual episodes per month dropped and the total sexual dysfunction score increased for before and after finasteride use according to the Arizona Sexual Experience Scale (P<0.0001 for both). The mean duration of finasteride use was 28 months and …
The mean number of sexual episodes per month dropped and the total sexual dysfunction score increased for before and after finasteride …
Depressive symptoms and suicidal thoughts among former users of finasteride with persistent sexual side effects.
Irwig MS. Irwig MS. J Clin Psychiatry. 2012 Sep;73(9):1220-3. doi: 10.4088/JCP.12m07887. Epub 2012 Aug 7. J Clin Psychiatry. 2012. PMID: 22939118
In addition, depression has recently been added to the product labeling of Propecia (finasteride 1 mg). Finasteride reduces the levels of several neuroactive steroids linked to sexual function and depression. This study assesses depressive symptoms and suicidal thou …
In addition, depression has recently been added to the product labeling of Propecia (finasteride 1 mg). Finasteride reduces th …
12 results