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Androgen receptor outwits prostate cancer drugs.
Isaacs JT, Isaacs WB. Isaacs JT, et al. Among authors: isaacs wb. Nat Med. 2004 Jan;10(1):26-7. doi: 10.1038/nm0104-26. Nat Med. 2004. PMID: 14702629 No abstract available.
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk.
Xu J, Zheng SL, Komiya A, Mychaleckyj JC, Isaacs SD, Hu JJ, Sterling D, Lange EM, Hawkins GA, Turner A, Ewing CM, Faith DA, Johnson JR, Suzuki H, Bujnovszky P, Wiley KE, DeMarzo AM, Bova GS, Chang B, Hall MC, McCullough DL, Partin AW, Kassabian VS, Carpten JD, Bailey-Wilson JE, Trent JM, Ohar J, Bleecker ER, Walsh PC, Isaacs WB, Meyers DA. Xu J, et al. Among authors: isaacs wb, isaacs sd. Nat Genet. 2002 Oct;32(2):321-5. doi: 10.1038/ng994. Epub 2002 Sep 16. Nat Genet. 2002. PMID: 12244320
Prostate cancer.
Nelson WG, De Marzo AM, Isaacs WB. Nelson WG, et al. Among authors: isaacs wb. N Engl J Med. 2003 Jul 24;349(4):366-81. doi: 10.1056/NEJMra021562. N Engl J Med. 2003. PMID: 12878745 Review. No abstract available.
Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer.
Liu W, Laitinen S, Khan S, Vihinen M, Kowalski J, Yu G, Chen L, Ewing CM, Eisenberger MA, Carducci MA, Nelson WG, Yegnasubramanian S, Luo J, Wang Y, Xu J, Isaacs WB, Visakorpi T, Bova GS. Liu W, et al. Among authors: isaacs wb. Nat Med. 2009 May;15(5):559-65. doi: 10.1038/nm.1944. Epub 2009 Apr 12. Nat Med. 2009. PMID: 19363497 Free PMC article.
Association of prostate cancer risk with SNPs in regions containing androgen receptor binding sites captured by ChIP-On-chip analyses.
Lu Y, Sun J, Kader AK, Kim ST, Kim JW, Liu W, Sun J, Lu D, Feng J, Zhu Y, Jin T, Zhang Z, Dimitrov L, Lowey J, Campbell K, Suh E, Duggan D, Carpten J, Trent JM, Gronberg H, Zheng SL, Isaacs WB, Xu J. Lu Y, et al. Among authors: isaacs wb. Prostate. 2012 Mar;72(4):376-85. doi: 10.1002/pros.21439. Epub 2011 Jun 10. Prostate. 2012. PMID: 21671247 Free PMC article.
A genome-wide survey over the ChIP-on-chip identified androgen receptor-binding genomic regions identifies a novel prostate cancer susceptibility locus at 12q13.13.
Feng J, Sun J, Kim ST, Lu Y, Wang Z, Zhang Z, Gronberg H, Isaacs WB, Zheng SL, Xu J. Feng J, et al. Among authors: isaacs wb. Cancer Epidemiol Biomarkers Prev. 2011 Nov;20(11):2396-403. doi: 10.1158/1055-9965.EPI-11-0523. Epub 2011 Sep 29. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21960693 Free PMC article.
The evolutionary history of lethal metastatic prostate cancer.
Gundem G, Van Loo P, Kremeyer B, Alexandrov LB, Tubio JMC, Papaemmanuil E, Brewer DS, Kallio HML, Högnäs G, Annala M, Kivinummi K, Goody V, Latimer C, O'Meara S, Dawson KJ, Isaacs W, Emmert-Buck MR, Nykter M, Foster C, Kote-Jarai Z, Easton D, Whitaker HC; ICGC Prostate Group, Neal DE, Cooper CS, Eeles RA, Visakorpi T, Campbell PJ, McDermott U, Wedge DC, Bova GS. Gundem G, et al. Nature. 2015 Apr 16;520(7547):353-357. doi: 10.1038/nature14347. Epub 2015 Apr 1. Nature. 2015. PMID: 25830880 Free PMC article.
Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors.
Zhu Y, Dalrymple SL, Coleman I, Zheng SL, Xu J, Hooper JE, Antonarakis ES, De Marzo AM, Meeker AK, Nelson PS, Isaacs WB, Denmeade SR, Luo J, Brennen WN, Isaacs JT. Zhu Y, et al. Among authors: isaacs wb, isaacs jt. Oncogene. 2020 Nov;39(45):6935-6949. doi: 10.1038/s41388-020-01479-6. Epub 2020 Sep 28. Oncogene. 2020. PMID: 32989253 Free PMC article.
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