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Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity.
BMC Med Genomics. 2011 Sep 29;4:68. doi: 10.1186/1755-8794-4-68.
BMC Med Genomics. 2011.
PMID: 21958464
Free PMC article.
The power of NGS technologies to delineate the genome organization in cancer: from mutations to structural variations and epigenetic alterations.
Schweiger MR, Kerick M, Timmermann B, Isau M.
Schweiger MR, et al. Among authors: isau m.
Cancer Metastasis Rev. 2011 Jun;30(2):199-210. doi: 10.1007/s10555-011-9278-z.
Cancer Metastasis Rev. 2011.
PMID: 21267768
Review.
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Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis.
Timmermann B, Kerick M, Roehr C, Fischer A, Isau M, Boerno ST, Wunderlich A, Barmeyer C, Seemann P, Koenig J, Lappe M, Kuss AW, Garshasbi M, Bertram L, Trappe K, Werber M, Herrmann BG, Zatloukal K, Lehrach H, Schweiger MR.
Timmermann B, et al. Among authors: isau m.
PLoS One. 2010 Dec 22;5(12):e15661. doi: 10.1371/journal.pone.0015661.
PLoS One. 2010.
PMID: 21203531
Free PMC article.
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Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation.
Börno ST, Fischer A, Kerick M, Fälth M, Laible M, Brase JC, Kuner R, Dahl A, Grimm C, Sayanjali B, Isau M, Röhr C, Wunderlich A, Timmermann B, Claus R, Plass C, Graefen M, Simon R, Demichelis F, Rubin MA, Sauter G, Schlomm T, Sültmann H, Lehrach H, Schweiger MR.
Börno ST, et al. Among authors: isau m.
Cancer Discov. 2012 Nov;2(11):1024-35. doi: 10.1158/2159-8290.CD-12-0041. Epub 2012 Aug 28.
Cancer Discov. 2012.
PMID: 22930729
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FOX-2 dependent splicing of ataxin-2 transcript is affected by ataxin-1 overexpression.
Welzel F, Kaehler C, Isau M, Hallen L, Lehrach H, Krobitsch S.
Welzel F, et al. Among authors: isau m.
PLoS One. 2012;7(5):e37985. doi: 10.1371/journal.pone.0037985. Epub 2012 May 30.
PLoS One. 2012.
PMID: 22666429
Free PMC article.
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Identity-by-descent filtering of exome sequence data identifies PIGV mutations in hyperphosphatasia mental retardation syndrome.
Krawitz PM, Schweiger MR, Rödelsperger C, Marcelis C, Kölsch U, Meisel C, Stephani F, Kinoshita T, Murakami Y, Bauer S, Isau M, Fischer A, Dahl A, Kerick M, Hecht J, Köhler S, Jäger M, Grünhagen J, de Condor BJ, Doelken S, Brunner HG, Meinecke P, Passarge E, Thompson MD, Cole DE, Horn D, Roscioli T, Mundlos S, Robinson PN.
Krawitz PM, et al. Among authors: isau m.
Nat Genet. 2010 Oct;42(10):827-9. doi: 10.1038/ng.653. Epub 2010 Aug 29.
Nat Genet. 2010.
PMID: 20802478
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Intersexual Twins due to Tetragametic Chimerism.
Wimmer R, Neumann U, Weber A, Isau M, Renner-Luetzkendorf H, Zschieschang P, Wachter O, Hirv K, Stumm M.
Wimmer R, et al. Among authors: isau m.
Cytogenet Genome Res. 2022;162(7):378-385. doi: 10.1159/000528737. Epub 2022 Dec 19.
Cytogenet Genome Res. 2022.
PMID: 36535241
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