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Newly established in vitro system with fluorescent proteins shows that abnormal expression of downstream prion protein-like protein in mice is probably due to functional disconnection between splicing and 3' formation of prion protein pre-mRNA.
Yoshikawa D, Kopacek J, Yamaguchi N, Ishibashi D, Yamanaka H, Yamaguchi Y, Katamine S, Sakaguchi S. Yoshikawa D, et al. Among authors: ishibashi d. Gene. 2007 Jan 15;386(1-2):139-46. doi: 10.1016/j.gene.2006.08.028. Epub 2006 Sep 15. Gene. 2007. PMID: 17034959
Direct evidence of generation and accumulation of β-sheet-rich prion protein in scrapie-infected neuroblastoma cells with human IgG1 antibody specific for β-form prion protein.
Kubota T, Hamazoe Y, Hashiguchi S, Ishibashi D, Akasaka K, Nishida N, Katamine S, Sakaguchi S, Kuroki R, Nakashima T, Sugimura K. Kubota T, et al. Among authors: ishibashi d. J Biol Chem. 2012 Apr 20;287(17):14023-39. doi: 10.1074/jbc.M111.318352. Epub 2012 Feb 22. J Biol Chem. 2012. PMID: 22356913 Free PMC article.
56 results