Ishikawa K - Search Results

1

Biological profiles of highly potent novel endothelin antagonists selective for the ETA receptor.

Ihara M, Noguchi K, Saeki T, Fukuroda T, Tsuchida S, Kimura S, Fukami T, Ishikawa K, Nishikibe M, Yano M. Ihara M, et al. Among authors: ishikawa k. Life Sci. 1992;50(4):247-55. doi: 10.1016/0024-3205(92)90331-i. Life Sci. 1992. PMID: 1310132

2

Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.

Ishikawa K, Ihara M, Noguchi K, Mase T, Mino N, Saeki T, Fukuroda T, Fukami T, Ozaki S, Nagase T, et al. Ishikawa K, et al. Proc Natl Acad Sci U S A. 1994 May 24;91(11):4892-6. doi: 10.1073/pnas.91.11.4892. Proc Natl Acad Sci U S A. 1994. PMID: 8197152 Free PMC article.

3

Antihypertensive effect of a newly synthesized endothelin antagonist, BQ-123, in a genetic hypertensive model.

Nishikibe M, Tsuchida S, Okada M, Fukuroda T, Shimamoto K, Yano M, Ishikawa K, Ikemoto F. Nishikibe M, et al. Among authors: ishikawa k. Life Sci. 1993;52(8):717-24. doi: 10.1016/0024-3205(93)90233-s. Life Sci. 1993. PMID: 8446001

4

Role of endothelin ETB receptors in bronchoconstrictor and vasoconstrictor responses in guinea-pigs.

Noguchi K, Noguchi Y, Hirose H, Nishikibe M, Ihara M, Ishikawa K, Yano M. Noguchi K, et al. Among authors: ishikawa k. Eur J Pharmacol. 1993 Mar 16;233(1):47-51. doi: 10.1016/0014-2999(93)90347-k. Eur J Pharmacol. 1993. PMID: 8472748

5

Synthesis and structure-activity relationships of 2-substituted D-tryptophan-containing peptidic endothelin receptor antagonists: importance of the C-2 substituent of the D-tryptophan residue for endothelin A and B receptor subtype selectivity.

Fukami T, Yamakawa T, Niiyama K, Kojima H, Amano Y, Kanda F, Ozaki S, Fukuroda T, Ihara M, Yano M, Ishikawa K. Fukami T, et al. Among authors: ishikawa k. J Med Chem. 1996 Jun 7;39(12):2313-30. doi: 10.1021/jm9600914. J Med Chem. 1996. PMID: 8691426

6

Cyclic pentapeptide endothelin A receptor antagonists with attenuated in vivo clearance.

Fukami T, Niiyama K, Amano Y, Hisaka A, Fujino N, Sawasaki Y, Ihara M, Ishikawa K. Fukami T, et al. Among authors: ishikawa k. Chem Pharm Bull (Tokyo). 1996 Mar;44(3):609-14. doi: 10.1248/cpb.44.609. Chem Pharm Bull (Tokyo). 1996. PMID: 8882459

7

Necessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin-1-induced contraction in human bronchi.

Fukuroda T, Ozaki S, Ihara M, Ishikawa K, Yano M, Miyauchi T, Ishikawa S, Onizuka M, Goto K, Nishikibe M. Fukuroda T, et al. Among authors: ishikawa s, ishikawa k. Br J Pharmacol. 1996 Mar;117(6):995-9. doi: 10.1111/j.1476-5381.1996.tb16688.x. Br J Pharmacol. 1996. PMID: 8882588 Free PMC article.

8

Coexpression studies with endothelin receptor subtypes indicate the existence of intracellular cross-talk between ET(A) and ET(B) receptors.

Ozaki S, Ohwaki K, Ihara M, Ishikawa K, Yano M. Ozaki S, et al. Among authors: ishikawa k. J Biochem. 1997 Mar;121(3):440-7. doi: 10.1093/oxfordjournals.jbchem.a021608. J Biochem. 1997. PMID: 9133612 Free article.

9

Pharmacological properties of J-104132 (L-753,037), a potent, orally active, mixed ETA/ETB endothelin receptor antagonist.

Nishikibe M, Ohta H, Okada M, Ishikawa K, Hayama T, Fukuroda T, Noguchi K, Saito M, Kanoh T, Ozaki S, Kamei T, Hara K, William D, Kivlighn S, Krause S, Gabel R, Zingaro G, Nolan N, O'Brien J, Clayton F, Lynch J, Pettibone D, Siegl P. Nishikibe M, et al. Among authors: ishikawa k. J Pharmacol Exp Ther. 1999 Jun;289(3):1262-70. J Pharmacol Exp Ther. 1999. PMID: 10336515

10

In vitro biological profile of a highly potent novel endothelin (ET) antagonist BQ-123 selective for the ETA receptor.

Ihara M, Ishikawa K, Fukuroda T, Saeki T, Funabashi K, Fukami T, Suda H, Yano M. Ihara M, et al. Among authors: ishikawa k. J Cardiovasc Pharmacol. 1992;20 Suppl 12:S11-4. doi: 10.1097/00005344-199204002-00005. J Cardiovasc Pharmacol. 1992. PMID: 1282942

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