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Inducible nitric oxide synthase up-regulates Notch-1 in mouse cholangiocytes: implications for carcinogenesis.
Ishimura N, Bronk SF, Gores GJ. Ishimura N, et al. Gastroenterology. 2005 May;128(5):1354-68. doi: 10.1053/j.gastro.2005.01.055. Gastroenterology. 2005. PMID: 15887117
The gamma-secretase inhibitor N-[N-(3,5-Difluorophenacetyl-L-alanyl)-S-phenylglycine]-t-butyl ester, which blocks Notch signaling, enhanced tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cholangiocarcinoma cells. ...
The gamma-secretase inhibitor N-[N-(3,5-Difluorophenacetyl-L-alanyl)-S-phenylglycine]-t-butyl ester, which blocks Notch signal …
Inducible nitric oxide synthase upregulates cyclooxygenase-2 in mouse cholangiocytes promoting cell growth.
Ishimura N, Bronk SF, Gores GJ. Ishimura N, et al. Am J Physiol Gastrointest Liver Physiol. 2004 Jul;287(1):G88-95. doi: 10.1152/ajpgi.00539.2003. Epub 2004 Feb 19. Am J Physiol Gastrointest Liver Physiol. 2004. PMID: 14977638
However, iNOS inhibition with either N-[3-(aminomethyl) benzyl]acetamidine or stable transfection with an iNOS antisense construct inhibited COX-2 mRNA and protein expression, an effect that was reversed by NO donors. ...
However, iNOS inhibition with either N-[3-(aminomethyl) benzyl]acetamidine or stable transfection with an iNOS antisense construct in …
Essential role of MD-2 in TLR4-dependent signaling during Helicobacter pylori-associated gastritis.
Ishihara S, Rumi MA, Kadowaki Y, Ortega-Cava CF, Yuki T, Yoshino N, Miyaoka Y, Kazumori H, Ishimura N, Amano Y, Kinoshita Y. Ishihara S, et al. J Immunol. 2004 Jul 15;173(2):1406-16. doi: 10.4049/jimmunol.173.2.1406. J Immunol. 2004. PMID: 15240737
Peroxisome proliferator-activated receptor gamma-dependent and -independent growth inhibition of gastrointestinal tumour cells.
Rumi MA, Ishihara S, Kadowaki Y, Ortega-Cava CF, Kazumori H, Kawashima K, Yoshino N, Yuki T, Ishimura N, Kinoshita Y. Rumi MA, et al. Genes Cells. 2004 Nov;9(11):1113-23. doi: 10.1111/j.1365-2443.2004.00793.x. Genes Cells. 2004. PMID: 15507122
Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells.
Ishimura N, Isomoto H, Bronk SF, Gores GJ. Ishimura N, et al. Am J Physiol Gastrointest Liver Physiol. 2006 Jan;290(1):G129-36. doi: 10.1152/ajpgi.00242.2005. Epub 2005 Sep 15. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16166346
Evaluation of modified crystal violet chromoendoscopy procedure using new mucosal pit pattern classification for detection of Barrett's dysplastic lesions.
Yuki T, Amano Y, Kushiyama Y, Takahashi Y, Ose T, Moriyama I, Fukuhara H, Ishimura N, Koshino K, Furuta K, Ishihara S, Adachi K, Kinoshita Y. Yuki T, et al. Dig Liver Dis. 2006 May;38(5):296-300. doi: 10.1016/j.dld.2006.01.028. Epub 2006 Mar 20. Dig Liver Dis. 2006. PMID: 16542886 Clinical Trial.
Ulinastatin shows preventive effect on post-endoscopic retrograde cholangiopancreatography pancreatitis in a multicenter prospective randomized study.
Fujishiro H, Adachi K, Imaoka T, Hashimoto T, Kohge N, Moriyama N, Suetsugu H, Kawashima K, Komazawa Y, Ishimura N, Ishihara S, Amano Y, Kinoshita Y. Fujishiro H, et al. J Gastroenterol Hepatol. 2006 Jun;21(6):1065-9. doi: 10.1111/j.1440-1746.2006.04085.x. J Gastroenterol Hepatol. 2006. PMID: 16724996 Clinical Trial.
Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins.
Baskin-Bey ES, Huang W, Ishimura N, Isomoto H, Bronk SF, Braley K, Craig RW, Moore DD, Gores GJ. Baskin-Bey ES, et al. Hepatology. 2006 Jul;44(1):252-62. doi: 10.1002/hep.21236. Hepatology. 2006. PMID: 16799968
REG Ialpha protein expression in Barrett's esophagus.
Chinuki D, Amano Y, Ishihara S, Moriyama N, Ishimura N, Kazumori H, Kadowaki Y, Takasawa S, Okamoto H, Kinoshita Y. Chinuki D, et al. J Gastroenterol Hepatol. 2008 Feb;23(2):296-302. doi: 10.1111/j.1440-1746.2007.04832.x. J Gastroenterol Hepatol. 2008. PMID: 18289358
Barrett's esophagus in Japanese patients: its prevalence, form, and elongation.
Okita K, Amano Y, Takahashi Y, Mishima Y, Moriyama N, Ishimura N, Ishihara S, Kinoshita Y. Okita K, et al. J Gastroenterol. 2008;43(12):928-34. doi: 10.1007/s00535-008-2261-y. Epub 2008 Dec 24. J Gastroenterol. 2008. PMID: 19107336
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