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111 results

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Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development.
Marx U, Akabane T, Andersson TB, Baker E, Beilmann M, Beken S, Brendler-Schwaab S, Cirit M, David R, Dehne EM, Durieux I, Ewart L, Fitzpatrick SC, Frey O, Fuchs F, Griffith LG, Hamilton GA, Hartung T, Hoeng J, Hogberg H, Hughes DJ, Ingber DE, Iskandar A, Kanamori T, Kojima H, Kuehnl J, Leist M, Li B, Loskill P, Mendrick DL, Neumann T, Pallocca G, Rusyn I, Smirnova L, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tsyb S, Trapecar M, Van de Water B, Van den Eijnden-van Raaij J, Vulto P, Watanabe K, Wolf A, Zhou X, Roth A. Marx U, et al. Among authors: iskandar a. ALTEX. 2020;37(3):365-394. doi: 10.14573/altex.2001241. Epub 2020 Feb 28. ALTEX. 2020. PMID: 32113184 Free PMC article.
Case study: the role of mechanistic network models in systems toxicology.
Hoeng J, Talikka M, Martin F, Sewer A, Yang X, Iskandar A, Schlage WK, Peitsch MC. Hoeng J, et al. Among authors: iskandar a. Drug Discov Today. 2014 Feb;19(2):183-92. doi: 10.1016/j.drudis.2013.07.023. Epub 2013 Aug 9. Drug Discov Today. 2014. PMID: 23933191 Review.
A framework for in vitro systems toxicology assessment of e-liquids.
Iskandar AR, Gonzalez-Suarez I, Majeed S, Marescotti D, Sewer A, Xiang Y, Leroy P, Guedj E, Mathis C, Schaller JP, Vanscheeuwijck P, Frentzel S, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Toxicol Mech Methods. 2016 Jul;26(6):389-413. doi: 10.3109/15376516.2016.1170251. Epub 2016 Apr 26. Toxicol Mech Methods. 2016. PMID: 27117495 Free PMC article.
Alternatives to Animal Use in Risk Assessment of Mixtures.
Wallace Hayes A, Muriana A, Alzualde A, Fernandez DB, Iskandar A, Peitsch MC, Kuczaj A, Hoeng J. Wallace Hayes A, et al. Among authors: iskandar a. Int J Toxicol. 2020 Mar/Apr;39(2):165-172. doi: 10.1177/1091581820905088. Epub 2020 Feb 18. Int J Toxicol. 2020. PMID: 32066298 Review.
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.
Schlage WK, Iskandar AR, Kostadinova R, Xiang Y, Sewer A, Majeed S, Kuehn D, Frentzel S, Talikka M, Geertz M, Mathis C, Ivanov N, Hoeng J, Peitsch MC. Schlage WK, et al. Among authors: iskandar ar. Toxicol Mech Methods. 2014 Oct;24(7):470-87. doi: 10.3109/15376516.2014.943441. Epub 2014 Sep 11. Toxicol Mech Methods. 2014. PMID: 25046638 Free PMC article.
Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.
Cabanski M, Fields B, Boue S, Boukharov N, DeLeon H, Dror N, Geertz M, Guedj E, Iskandar A, Kogel U, Merg C, Peck MJ, Poussin C, Schlage WK, Talikka M, Ivanov NV, Hoeng J, Peitsch MC. Cabanski M, et al. Among authors: iskandar a. Inflamm Res. 2015 Jul;64(7):471-86. doi: 10.1007/s00011-015-0820-2. Epub 2015 May 12. Inflamm Res. 2015. PMID: 25962837 Free PMC article.
111 results