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Angiopoietin-1 reduces H(2)O(2)-induced increases in reactive oxygen species and oxidative damage to skin cells.

Ismail NS, Pravda EA, Li D, Shih SC, Dallabrida SM. Ismail NS, et al. J Invest Dermatol. 2010 May;130(5):1307-17. doi: 10.1038/jid.2009.431. Epub 2010 Jan 14. J Invest Dermatol. 2010. PMID: 20072135 Free article.

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Angiopoietin-1 promotes cardiac and skeletal myocyte survival through integrins.

Dallabrida SM, Ismail N, Oberle JR, Himes BE, Rupnick MA. Dallabrida SM, et al. Circ Res. 2005 Mar 4;96(4):e8-24. doi: 10.1161/01.RES.0000158285.57191.60. Epub 2005 Feb 3. Circ Res. 2005. PMID: 15692086

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Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy.

Dallabrida SM, Ismail NS, Pravda EA, Parodi EM, Dickie R, Durand EM, Lai J, Cassiola F, Rogers RA, Rupnick MA. Dallabrida SM, et al. Among authors: ismail ns. FASEB J. 2008 Aug;22(8):3010-23. doi: 10.1096/fj.07-100966. Epub 2008 May 23. FASEB J. 2008. PMID: 18502941 Free PMC article.

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Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition.

Sunshine SB, Dallabrida SM, Durand E, Ismail NS, Bazinet L, Birsner AE, Sohn R, Ikeda S, Pu WT, Kulke MH, Javaherian K, Zurakowski D, Folkman JM, Rupnick M. Sunshine SB, et al. Among authors: ismail ns. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11306-11. doi: 10.1073/pnas.1203275109. Epub 2012 Jun 25. Proc Natl Acad Sci U S A. 2012. PMID: 22733742 Free PMC article.

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Photocrosslinkable chitosan modified with angiopoietin-1 peptide, QHREDGS, promotes survival of neonatal rat heart cells.

Rask F, Dallabrida SM, Ismail NS, Amoozgar Z, Yeo Y, Rupnick MA, Radisic M. Rask F, et al. Among authors: ismail ns. J Biomed Mater Res A. 2010 Oct;95(1):105-17. doi: 10.1002/jbm.a.32808. J Biomed Mater Res A. 2010. PMID: 20540095

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Contrary effects of the receptor tyrosine kinase inhibitor vandetanib on constitutive and flow-stimulated nitric oxide elaboration in humans.

Mayer EL, Dallabrida SM, Rupnick MA, Redline WM, Hannagan K, Ismail NS, Burstein HJ, Beckman JA. Mayer EL, et al. Among authors: ismail ns. Hypertension. 2011 Jul;58(1):85-92. doi: 10.1161/HYPERTENSIONAHA.110.168120. Epub 2011 Apr 11. Hypertension. 2011. PMID: 21482957 Free PMC article. Clinical Trial.

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QHREDGS enhances tube formation, metabolism and survival of endothelial cells in collagen-chitosan hydrogels.

Miklas JW, Dallabrida SM, Reis LA, Ismail N, Rupnick M, Radisic M. Miklas JW, et al. PLoS One. 2013 Aug 27;8(8):e72956. doi: 10.1371/journal.pone.0072956. eCollection 2013. PLoS One. 2013. PMID: 24013716 Free PMC article.

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Cardiotoxicity associated with tyrosine kinase inhibitor sunitinib.

Chu TF, Rupnick MA, Kerkela R, Dallabrida SM, Zurakowski D, Nguyen L, Woulfe K, Pravda E, Cassiola F, Desai J, George S, Morgan JA, Harris DM, Ismail NS, Chen JH, Schoen FJ, Van den Abbeele AD, Demetri GD, Force T, Chen MH. Chu TF, et al. Among authors: ismail ns. Lancet. 2007 Dec 15;370(9604):2011-9. doi: 10.1016/S0140-6736(07)61865-0. Lancet. 2007. PMID: 18083403 Free PMC article.

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GP369, an FGFR2-IIIb-specific antibody, exhibits potent antitumor activity against human cancers driven by activated FGFR2 signaling.

Bai A, Meetze K, Vo NY, Kollipara S, Mazsa EK, Winston WM, Weiler S, Poling LL, Chen T, Ismail NS, Jiang J, Lerner L, Gyuris J, Weng Z. Bai A, et al. Among authors: ismail ns. Cancer Res. 2010 Oct 1;70(19):7630-9. doi: 10.1158/0008-5472.CAN-10-1489. Epub 2010 Aug 13. Cancer Res. 2010. PMID: 20709759

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Synthesis, biological evaluation, and in silico studies of new CDK2 inhibitors based on pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold with apoptotic activity.

Mandour AA, Nassar IF, Abdel Aal MT, Shahin MAE, El-Sayed WA, Hegazy M, Yehia AM, Ismail A, Hagras M, Elkaeed EB, Refaat HM, Ismail NSM. Mandour AA, et al. Among authors: ismail nsm. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1957-1973. doi: 10.1080/14756366.2022.2086866. J Enzyme Inhib Med Chem. 2022. PMID: 35815597 Free PMC article.

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