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New mechanism of X-linked anhidrotic ectodermal dysplasia with immunodeficiency: impairment of ubiquitin binding despite normal folding of NEMO protein.
Hubeau M, Ngadjeua F, Puel A, Israel L, Feinberg J, Chrabieh M, Belani K, Bodemer C, Fabre I, Plebani A, Boisson-Dupuis S, Picard C, Fischer A, Israel A, Abel L, Veron M, Casanova JL, Agou F, Bustamante J. Hubeau M, et al. Among authors: israel a, israel l. Blood. 2011 Jul 28;118(4):926-35. doi: 10.1182/blood-2010-10-315234. Epub 2011 May 26. Blood. 2011. PMID: 21622647 Free PMC article.
IKK regulation and human genetics.
Courtois G, Israël A. Courtois G, et al. Among authors: israel a. Curr Top Microbiol Immunol. 2011;349:73-95. doi: 10.1007/82_2010_98. Curr Top Microbiol Immunol. 2011. PMID: 20845108 Review.
Osteopetrosis, lymphedema, anhidrotic ectodermal dysplasia, and immunodeficiency in a boy and incontinentia pigmenti in his mother.
Dupuis-Girod S, Corradini N, Hadj-Rabia S, Fournet JC, Faivre L, Le Deist F, Durand P, Döffinger R, Smahi A, Israel A, Courtois G, Brousse N, Blanche S, Munnich A, Fischer A, Casanova JL, Bodemer C. Dupuis-Girod S, et al. Among authors: israel a. Pediatrics. 2002 Jun;109(6):e97. doi: 10.1542/peds.109.6.e97. Pediatrics. 2002. PMID: 12042591
A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency.
Courtois G, Smahi A, Reichenbach J, Döffinger R, Cancrini C, Bonnet M, Puel A, Chable-Bessia C, Yamaoka S, Feinberg J, Dupuis-Girod S, Bodemer C, Livadiotti S, Novelli F, Rossi P, Fischer A, Israël A, Munnich A, Le Deist F, Casanova JL. Courtois G, et al. Among authors: israel a. J Clin Invest. 2003 Oct;112(7):1108-15. doi: 10.1172/JCI18714. J Clin Invest. 2003. PMID: 14523047 Free PMC article.
Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization.
Agou F, Courtois G, Chiaravalli J, Baleux F, Coïc YM, Traincard F, Israël A, Véron M. Agou F, et al. Among authors: israel a. J Biol Chem. 2004 Dec 24;279(52):54248-57. doi: 10.1074/jbc.M406423200. Epub 2004 Oct 5. J Biol Chem. 2004. PMID: 15466857
NF-kappa B essential modulator/IKK-gamma (NEMO/IKK-gamma) plays a key role in the activation of the NF-kappa B pathway in response to proinflammatory stimuli. ...The minimal oligomerization domain of this protein consists of two coiled-coil subdomains named Coiled-coil 2 ( …
NF-kappa B essential modulator/IKK-gamma (NEMO/IKK-gamma) plays a key role in the activation of the NF-kappa B pathway in response to …
Mature T cells depend on signaling through the IKK complex.
Schmidt-Supprian M, Courtois G, Tian J, Coyle AJ, Israël A, Rajewsky K, Pasparakis M. Schmidt-Supprian M, et al. Among authors: israel a. Immunity. 2003 Sep;19(3):377-89. doi: 10.1016/s1074-7613(03)00237-1. Immunity. 2003. PMID: 14499113
The IKK complex contributes to the induction of autophagy.
Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, Tailler M, Delahaye N, Tesniere A, De Stefano D, Younes AB, Harper F, Pierron G, Lavandero S, Zitvogel L, Israel A, Baud V, Kroemer G. Criollo A, et al. Among authors: israel a. EMBO J. 2010 Feb 3;29(3):619-31. doi: 10.1038/emboj.2009.364. Epub 2009 Dec 3. EMBO J. 2010. PMID: 19959994 Free PMC article.
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