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49 results
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Interpretation of large-scale quantitative shotgun proteomic profiles for biomarker discovery.
Isserlin R, Emili A. Isserlin R, et al. Curr Opin Mol Ther. 2008 Jun;10(3):231-42. Curr Opin Mol Ther. 2008. PMID: 18535930 Review.
Comparative proteomics profiling of a phospholamban mutant mouse model of dilated cardiomyopathy reveals progressive intracellular stress responses.
Gramolini AO, Kislinger T, Alikhani-Koopaei R, Fong V, Thompson NJ, Isserlin R, Sharma P, Oudit GY, Trivieri MG, Fagan A, Kannan A, Higgins DG, Huedig H, Hess G, Arab S, Seidman JG, Seidman CE, Frey B, Perry M, Backx PH, Liu PP, MacLennan DH, Emili A. Gramolini AO, et al. Among authors: isserlin r. Mol Cell Proteomics. 2008 Mar;7(3):519-33. doi: 10.1074/mcp.M700245-MCP200. Epub 2007 Nov 30. Mol Cell Proteomics. 2008. PMID: 18056057
Large-scale characterization and analysis of the murine cardiac proteome.
Bousette N, Kislinger T, Fong V, Isserlin R, Hewel JA, Emil A, Gramolini AO. Bousette N, et al. Among authors: isserlin r. J Proteome Res. 2009 Apr;8(4):1887-901. doi: 10.1021/pr800845a. J Proteome Res. 2009. PMID: 19714876
Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps.
Isserlin R, Merico D, Alikhani-Koupaei R, Gramolini A, Bader GD, Emili A. Isserlin R, et al. Proteomics. 2010 Mar;10(6):1316-27. doi: 10.1002/pmic.200900412. Proteomics. 2010. PMID: 20127684 Free PMC article.
A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.
Mak AB, Ni Z, Hewel JA, Chen GI, Zhong G, Karamboulas K, Blakely K, Smiley S, Marcon E, Roudeva D, Li J, Olsen JB, Wan C, Punna T, Isserlin R, Chetyrkin S, Gingras AC, Emili A, Greenblatt J, Moffat J. Mak AB, et al. Among authors: isserlin r. Mol Cell Proteomics. 2010 May;9(5):811-23. doi: 10.1074/mcp.M000002-MCP201. Epub 2010 Mar 19. Mol Cell Proteomics. 2010. PMID: 20305087 Free PMC article.
Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by alpha-crystallin-B.
Bousette N, Chugh S, Fong V, Isserlin R, Kim KH, Volchuk A, Backx PH, Liu P, Kislinger T, MacLennan DH, Emili A, Gramolini AO. Bousette N, et al. Among authors: isserlin r. Proc Natl Acad Sci U S A. 2010 Oct 26;107(43):18481-6. doi: 10.1073/pnas.1013555107. Epub 2010 Oct 11. Proc Natl Acad Sci U S A. 2010. PMID: 20937869 Free PMC article.
Enrichment map: a network-based method for gene-set enrichment visualization and interpretation.
Merico D, Isserlin R, Stueker O, Emili A, Bader GD. Merico D, et al. Among authors: isserlin r. PLoS One. 2010 Nov 15;5(11):e13984. doi: 10.1371/journal.pone.0013984. PLoS One. 2010. PMID: 21085593 Free PMC article.
Nine steps to proteomic wisdom: A practical guide to using protein-protein interaction networks and molecular pathways as a framework for interpreting disease proteomic profiles.
Isserlin R, Emili A. Isserlin R, et al. Proteomics Clin Appl. 2007 Sep;1(9):1156-68. doi: 10.1002/prca.200700146. Epub 2007 Aug 17. Proteomics Clin Appl. 2007. PMID: 21136765
The Biomolecular Interaction Network Database in PSI-MI 2.5.
Isserlin R, El-Badrawi RA, Bader GD. Isserlin R, et al. Database (Oxford). 2011 Jan 12;2011:baq037. doi: 10.1093/database/baq037. Print 2011. Database (Oxford). 2011. PMID: 21233089 Free PMC article.
Integrative network analysis of signaling in human CD34(+) hematopoietic progenitor cells by global phosphoproteomic profiling using TiO2 enrichment combined with 2D LC-MS/MS and pathway mapping.
Guo H, Isserlin R, Chen X, Wang W, Phanse S, Zandstra PW, Paddison PJ, Emili A. Guo H, et al. Among authors: isserlin r. Proteomics. 2013 Apr;13(8):1325-33. doi: 10.1002/pmic.201200369. Epub 2013 Mar 6. Proteomics. 2013. PMID: 23401153 Free PMC article.
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