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Spatial transcriptomics of murine bone marrow megakaryocytes at single-cell resolution.
Tilburg J, Stone AP, Billingsley JM, Scoville DK, Pavenko A, Liang Y, Italiano JE Jr, Machlus KR. Tilburg J, et al. Among authors: italiano je jr. Res Pract Thromb Haemost. 2023 Apr 20;7(4):100158. doi: 10.1016/j.rpth.2023.100158. eCollection 2023 May. Res Pract Thromb Haemost. 2023. PMID: 37255850 Free PMC article.
Pro-inflammatory megakaryocyte gene expression in murine models of breast cancer.
Roweth HG, Malloy MW, Goreczny GJ, Becker IC, Guo Q, Mittendorf EA, Italiano JE Jr, McAllister SS, Battinelli EM. Roweth HG, et al. Among authors: italiano je jr. Sci Adv. 2022 Oct 14;8(41):eabo5224. doi: 10.1126/sciadv.abo5224. Epub 2022 Oct 12. Sci Adv. 2022. PMID: 36223471 Free PMC article.
Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates.
Slingsby MHL, Vijey P, Tsai IT, Roweth H, Couldwell G, Wilkie AR, Gaus H, Goolsby JM, Okazaki R, Terkovich BE, Semple JW, Thon JN, Henry SP, Narayanan P, Italiano JE Jr. Slingsby MHL, et al. Among authors: italiano je jr. Haematologica. 2022 Feb 1;107(2):519-531. doi: 10.3324/haematol.2020.260059. Haematologica. 2022. PMID: 33567808 Free PMC article.
High-content, label-free analysis of proplatelet production from megakaryocytes.
French SL, Vijey P, Karhohs KW, Wilkie AR, Horin LJ, Ray A, Posorske B, Carpenter AE, Machlus KR, Italiano JE Jr. French SL, et al. Among authors: italiano je jr. J Thromb Haemost. 2020 Oct;18(10):2701-2711. doi: 10.1111/jth.15012. Epub 2020 Aug 23. J Thromb Haemost. 2020. PMID: 32662223 Free PMC article.
Aspirin inhibits platelets from reprogramming breast tumor cells and promoting metastasis.
Johnson KE, Ceglowski JR, Roweth HG, Forward JA, Tippy MD, El-Husayni S, Kulenthirarajan R, Malloy MW, Machlus KR, Chen WY, Italiano JE Jr, Battinelli EM. Johnson KE, et al. Among authors: italiano je jr. Blood Adv. 2019 Jan 22;3(2):198-211. doi: 10.1182/bloodadvances.2018026161. Blood Adv. 2019. PMID: 30670536 Free PMC article.
Unlocking the Molecular Secrete(s) of α-Granule Biogenesis.
Noetzli LJ, Italiano JE Jr. Noetzli LJ, et al. Among authors: italiano je jr. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2539-2541. doi: 10.1161/ATVBAHA.118.311614. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354241 Free PMC article. No abstract available.
Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice.
Paul DS, Casari C, Wu C, Piatt R, Pasala S, Campbell RA, Poe KO, Ghalloussi D, Lee RH, Rotty JD, Cooley BC, Machlus KR, Italiano JE Jr, Weyrich AS, Bear JE, Bergmeier W. Paul DS, et al. Among authors: italiano je jr. Blood Adv. 2017 Aug 8;1(18):1398-1408. doi: 10.1182/bloodadvances.2017006973. Blood Adv. 2017. PMID: 29104956 Free PMC article.
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