Itasaka S - Search Results

1

The combination of hypoxia-response enhancers and an oxygen-dependent proteolytic motif enables real-time imaging of absolute HIF-1 activity in tumor xenografts.

Harada H, Kizaka-Kondoh S, Itasaka S, Shibuya K, Morinibu A, Shinomiya K, Hiraoka M. Harada H, et al. Among authors: itasaka s. Biochem Biophys Res Commun. 2007 Sep 7;360(4):791-6. doi: 10.1016/j.bbrc.2007.06.149. Epub 2007 Jul 5. Biochem Biophys Res Commun. 2007. PMID: 17624305

2

Evaluation of glass microspheres for intra-arterial radiotherapy in animal kidneys.

Araki N, Nagata Y, Fujiwara K, Aoki T, Mitsumori M, Kimura H, Itasaka S, Saitou H, Hiraoka M, Kawashita M, Kokubo T. Araki N, et al. Among authors: itasaka s. Int J Radiat Oncol Biol Phys. 2001 Feb 1;49(2):459-63. doi: 10.1016/s0360-3016(00)01473-5. Int J Radiat Oncol Biol Phys. 2001. PMID: 11173141

3

Endostatin improves radioresponse and blocks tumor revascularization after radiation therapy for A431 xenografts in mice.

Itasaka S, Komaki R, Herbst RS, Shibuya K, Shintani T, Hunter NR, Onn A, Bucana CD, Milas L, Ang KK, O'Reilly MS. Itasaka S, et al. Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):870-8. doi: 10.1016/j.ijrobp.2006.10.030. Int J Radiat Oncol Biol Phys. 2007. PMID: 17293237 Free PMC article.

4

Significance of HIF-1-active cells in angiogenesis and radioresistance.

Harada H, Kizaka-Kondoh S, Li G, Itasaka S, Shibuya K, Inoue M, Hiraoka M. Harada H, et al. Among authors: itasaka s. Oncogene. 2007 Nov 29;26(54):7508-16. doi: 10.1038/sj.onc.1210556. Epub 2007 Jun 11. Oncogene. 2007. PMID: 17563752

5

Hypoxia inducible factor-1 influences sensitivity to paclitaxel of human lung cancer cell lines under normoxic conditions.

Zeng L, Kizaka-Kondoh S, Itasaka S, Xie X, Inoue M, Tanimoto K, Shibuya K, Hiraoka M. Zeng L, et al. Among authors: itasaka s. Cancer Sci. 2007 Sep;98(9):1394-401. doi: 10.1111/j.1349-7006.2007.00537.x. Epub 2007 Jun 30. Cancer Sci. 2007. PMID: 17608771 Free article.

6

Targeted therapy against VEGFR and EGFR with ZD6474 enhances the therapeutic efficacy of irradiation in an orthotopic model of human non-small-cell lung cancer.

Shibuya K, Komaki R, Shintani T, Itasaka S, Ryan A, Jürgensmeier JM, Milas L, Ang K, Herbst RS, O'Reilly MS. Shibuya K, et al. Among authors: itasaka s. Int J Radiat Oncol Biol Phys. 2007 Dec 1;69(5):1534-43. doi: 10.1016/j.ijrobp.2007.07.2350. Epub 2007 Sep 24. Int J Radiat Oncol Biol Phys. 2007. PMID: 17889445 Free PMC article.

7

Diameter of tumor blood vessels is a good parameter to estimate HIF-1-active regions in solid tumors.

Harada H, Xie X, Itasaka S, Zeng L, Zhu Y, Morinibu A, Shinomiya K, Hiraoka M. Harada H, et al. Among authors: itasaka s. Biochem Biophys Res Commun. 2008 Sep 5;373(4):533-8. doi: 10.1016/j.bbrc.2008.06.062. Epub 2008 Jun 27. Biochem Biophys Res Commun. 2008. PMID: 18586004

8

TS-1 enhances the effect of radiotherapy by suppressing radiation-induced hypoxia-inducible factor-1 activation and inducing endothelial cell apoptosis.

Zeng L, Ou G, Itasaka S, Harada H, Xie X, Shibuya K, Kizaka-Kondoh S, Morinibu A, Shinomiya K, Hiraoka M. Zeng L, et al. Among authors: itasaka s. Cancer Sci. 2008 Nov;99(11):2327-35. doi: 10.1111/j.1349-7006.2008.00943.x. Epub 2008 Sep 22. Cancer Sci. 2008. PMID: 18823375 Free article.

9

The Akt/mTOR pathway assures the synthesis of HIF-1alpha protein in a glucose- and reoxygenation-dependent manner in irradiated tumors.

Harada H, Itasaka S, Kizaka-Kondoh S, Shibuya K, Morinibu A, Shinomiya K, Hiraoka M. Harada H, et al. Among authors: itasaka s. J Biol Chem. 2009 Feb 20;284(8):5332-42. doi: 10.1074/jbc.M806653200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19098000 Free article.

10

Treatment regimen determines whether an HIF-1 inhibitor enhances or inhibits the effect of radiation therapy.

Harada H, Itasaka S, Zhu Y, Zeng L, Xie X, Morinibu A, Shinomiya K, Hiraoka M. Harada H, et al. Among authors: itasaka s. Br J Cancer. 2009 Mar 10;100(5):747-57. doi: 10.1038/sj.bjc.6604939. Epub 2009 Feb 17. Br J Cancer. 2009. PMID: 19223896 Free PMC article.

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