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The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.
Hassler JR, Scheuner DL, Wang S, Han J, Kodali VK, Li P, Nguyen J, George JS, Davis C, Wu SP, Bai Y, Sartor M, Cavalcoli J, Malhi H, Baudouin G, Zhang Y, Yates JR III, Itkin-Ansari P, Volkmann N, Kaufman RJ. Hassler JR, et al. PLoS Biol. 2015 Oct 15;13(10):e1002277. doi: 10.1371/journal.pbio.1002277. eCollection 2015 Oct. PLoS Biol. 2015. PMID: 26469762 Free PMC article.
Proinsulin misfolding is an early event in the progression to type 2 diabetes.
Arunagiri A, Haataja L, Pottekat A, Pamenan F, Kim S, Zeltser LM, Paton AW, Paton JC, Tsai B, Itkin-Ansari P, Kaufman RJ, Liu M, Arvan P. Arunagiri A, et al. Among authors: itkin ansari p. Elife. 2019 Jun 11;8:e44532. doi: 10.7554/eLife.44532. Elife. 2019. PMID: 31184302 Free PMC article.
Inflammatory Cytokines Rewire the Proinsulin Interaction Network in Human Islets.
Tran DT, Pottekat A, Lee K, Raghunathan M, Loguercio S, Mir SA, Paton AW, Paton JC, Arvan P, Kaufman RJ, Itkin-Ansari P. Tran DT, et al. Among authors: itkin ansari p. J Clin Endocrinol Metab. 2022 Nov 23;107(11):3100-3110. doi: 10.1210/clinem/dgac493. J Clin Endocrinol Metab. 2022. PMID: 36017587 Free PMC article.
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