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10,086 results
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Histone acetylation and histone deacetylation.
Ito K, Adcock IM. Ito K, et al. Mol Biotechnol. 2002 Jan;20(1):99-106. doi: 10.1385/MB:20:1:099. Mol Biotechnol. 2002. PMID: 11876304
Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1beta-induced histone H4 acetylation on lysines 8 and 12.
Ito K, Barnes PJ, Adcock IM. Ito K, et al. Mol Cell Biol. 2000 Sep;20(18):6891-903. doi: 10.1128/mcb.20.18.6891-6903.2000. Mol Cell Biol. 2000. PMID: 10958685 Free PMC article.
Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages.
Ito K, Lim S, Caramori G, Chung KF, Barnes PJ, Adcock IM. Ito K, et al. FASEB J. 2001 Apr;15(6):1110-2. FASEB J. 2001. PMID: 11292684 No abstract available.
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo.
Vigushin DM, Ali S, Pace PE, Mirsaidi N, Ito K, Adcock I, Coombes RC. Vigushin DM, et al. Among authors: ito k. Clin Cancer Res. 2001 Apr;7(4):971-6. Clin Cancer Res. 2001. PMID: 11309348
p65-activated histone acetyltransferase activity is repressed by glucocorticoids: mifepristone fails to recruit HDAC2 to the p65-HAT complex.
Ito K, Jazrawi E, Cosio B, Barnes PJ, Adcock IM. Ito K, et al. J Biol Chem. 2001 Aug 10;276(32):30208-15. doi: 10.1074/jbc.M103604200. Epub 2001 Jun 6. J Biol Chem. 2001. PMID: 11395507
Glucocorticoid-mediated transrepression is regulated by histone acetylation and DNA methylation.
Kagoshima M, Wilcke T, Ito K, Tsaprouni L, Barnes PJ, Punchard N, Adcock IM. Kagoshima M, et al. Among authors: ito k. Eur J Pharmacol. 2001 Oct 19;429(1-3):327-34. doi: 10.1016/s0014-2999(01)01332-2. Eur J Pharmacol. 2001. PMID: 11698053
A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression.
Ito K, Lim S, Caramori G, Cosio B, Chung KF, Adcock IM, Barnes PJ. Ito K, et al. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8921-6. doi: 10.1073/pnas.132556899. Epub 2002 Jun 17. Proc Natl Acad Sci U S A. 2002. PMID: 12070353 Free PMC article. Clinical Trial.
Expression and activity of histone deacetylases in human asthmatic airways.
Ito K, Caramori G, Lim S, Oates T, Chung KF, Barnes PJ, Adcock IM. Ito K, et al. Am J Respir Crit Care Med. 2002 Aug 1;166(3):392-6. doi: 10.1164/rccm.2110060. Am J Respir Crit Care Med. 2002. PMID: 12153977
Increased p21(CIP1/WAF1) and B cell lymphoma leukemia-x(L) expression and reduced apoptosis in alveolar macrophages from smokers.
Tomita K, Caramori G, Lim S, Ito K, Hanazawa T, Oates T, Chiselita I, Jazrawi E, Chung KF, Barnes PJ, Adcock IM. Tomita K, et al. Among authors: ito k. Am J Respir Crit Care Med. 2002 Sep 1;166(5):724-31. doi: 10.1164/rccm.2104010. Am J Respir Crit Care Med. 2002. PMID: 12204872
Triamcinolone acetonide and dexamethasome suppress TNF-alpha-induced histone H4 acetylation on lysine residues 8 and 12 in mononuclear cells.
Tsaprouni LG, Ito K, Punchard N, Adcock IM. Tsaprouni LG, et al. Among authors: ito k. Ann N Y Acad Sci. 2002 Nov;973:481-3. doi: 10.1111/j.1749-6632.2002.tb04688.x. Ann N Y Acad Sci. 2002. PMID: 12485916 No abstract available.
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