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Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial.
Voskuhl RR, Wang H, Wu TC, Sicotte NL, Nakamura K, Kurth F, Itoh N, Bardens J, Bernard JT, Corboy JR, Cross AH, Dhib-Jalbut S, Ford CC, Frohman EM, Giesser B, Jacobs D, Kasper LH, Lynch S, Parry G, Racke MK, Reder AT, Rose J, Wingerchuk DM, MacKenzie-Graham AJ, Arnold DL, Tseng CH, Elashoff R. Voskuhl RR, et al. Among authors: Itoh N. Lancet Neurol. 2016 Jan;15(1):35-46. doi: 10.1016/S1474-4422(15)00322-1. Epub 2015 Nov 29. Lancet Neurol. 2016. PMID: 26621682 Clinical Trial.
FUNDING: National Institutes of Health, National Multiple Sclerosis Society, Conrad N Hilton Foundation, Jack H Skirball Foundation, Sherak Family Foundation, and the California Community Foundation....
FUNDING: National Institutes of Health, National Multiple Sclerosis Society, Conrad N Hilton Foundation, Jack H Skirball Foundation, …
Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes.
Itoh N, Itoh Y, Tassoni A, Ren E, Kaito M, Ohno A, Ao Y, Farkhondeh V, Johnsonbaugh H, Burda J, Sofroniew MV, Voskuhl RR. Itoh N, et al. Among authors: Itoh Y. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):E302-E309. doi: 10.1073/pnas.1716032115. Epub 2017 Dec 26. Proc Natl Acad Sci U S A. 2018. PMID: 29279367 Free PMC article.
Gene expression in oligodendrocytes during remyelination reveals cholesterol homeostasis as a therapeutic target in multiple sclerosis.
Voskuhl RR, Itoh N, Tassoni A, Matsukawa MA, Ren E, Tse V, Jang E, Suen TT, Itoh Y. Voskuhl RR, et al. Among authors: Itoh N, Itoh Y. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10130-10139. doi: 10.1073/pnas.1821306116. Epub 2019 Apr 30. Proc Natl Acad Sci U S A. 2019. PMID: 31040210 Free PMC article.
Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand.
Khalaj AJ, Yoon J, Nakai J, Winchester Z, Moore SM, Yoo T, Martinez-Torres L, Kumar S, Itoh N, Tiwari-Woodruff SK. Khalaj AJ, et al. Among authors: Itoh N. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19125-30. doi: 10.1073/pnas.1311763110. Epub 2013 Nov 4. Proc Natl Acad Sci U S A. 2013. PMID: 24191028 Free PMC article.
XY sex chromosome complement, compared with XX, in the CNS confers greater neurodegeneration during experimental autoimmune encephalomyelitis.
Du S, Itoh N, Askarinam S, Hill H, Arnold AP, Voskuhl RR. Du S, et al. Among authors: Itoh N. Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2806-11. doi: 10.1073/pnas.1307091111. Epub 2014 Feb 3. Proc Natl Acad Sci U S A. 2014. PMID: 24550311 Free PMC article.
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