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2,201 results
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Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4.
Morén A, Itoh S, Moustakas A, Dijke P, Heldin CH. Morén A, et al. Among authors: itoh s. Oncogene. 2000 Sep 7;19(38):4396-404. doi: 10.1038/sj.onc.1203798. Oncogene. 2000. PMID: 10980615
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling.
Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P. Nakao A, et al. Among authors: itoh s. Nature. 1997 Oct 9;389(6651):631-5. doi: 10.1038/39369. Nature. 1997. PMID: 9335507
Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.
Dennler S, Itoh S, Vivien D, ten Dijke P, Huet S, Gauthier JM. Dennler S, et al. Among authors: itoh s. EMBO J. 1998 Jun 1;17(11):3091-100. doi: 10.1093/emboj/17.11.3091. EMBO J. 1998. PMID: 9606191 Free PMC article.
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer.
Jonk LJ, Itoh S, Heldin CH, ten Dijke P, Kruijer W. Jonk LJ, et al. Among authors: itoh s. J Biol Chem. 1998 Aug 14;273(33):21145-52. doi: 10.1074/jbc.273.33.21145. J Biol Chem. 1998. PMID: 9694870
Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members.
Afrakhte M, Morén A, Jossan S, Itoh S, Sampath K, Westermark B, Heldin CH, Heldin NE, ten Dijke P. Afrakhte M, et al. Among authors: itoh s. Biochem Biophys Res Commun. 1998 Aug 19;249(2):505-11. doi: 10.1006/bbrc.1998.9170. Biochem Biophys Res Commun. 1998. PMID: 9712726
The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation.
Persson U, Izumi H, Souchelnytskyi S, Itoh S, Grimsby S, Engström U, Heldin CH, Funa K, ten Dijke P. Persson U, et al. Among authors: itoh s. FEBS Lett. 1998 Aug 28;434(1-2):83-7. doi: 10.1016/s0014-5793(98)00954-5. FEBS Lett. 1998. PMID: 9738456
Intracellular signaling of osteogenic protein-1 through Smad5 activation.
Tamaki K, Souchelnytskyi S, Itoh S, Nakao A, Sampath K, Heldin CH, ten Dijke P. Tamaki K, et al. Among authors: itoh s. J Cell Physiol. 1998 Nov;177(2):355-63. doi: 10.1002/(SICI)1097-4652(199811)177:2<355::AID-JCP17>3.0.CO;2-8. J Cell Physiol. 1998. PMID: 9766532
Transforming growth factor beta1 induces nuclear export of inhibitory Smad7.
Itóh S, Landström M, Hermansson A, Itoh F, Heldin CH, Heldin NE, ten Dijke P. Itóh S, et al. Among authors: itoh f. J Biol Chem. 1998 Oct 30;273(44):29195-201. doi: 10.1074/jbc.273.44.29195. J Biol Chem. 1998. PMID: 9786930
Xenopus Smad4beta is the co-Smad component of developmentally regulated transcription factor complexes responsible for induction of early mesodermal genes.
Howell M, Itoh F, Pierreux CE, Valgeirsdottir S, Itoh S, ten Dijke P, Hill CS. Howell M, et al. Among authors: itoh f, itoh s. Dev Biol. 1999 Oct 15;214(2):354-69. doi: 10.1006/dbio.1999.9430. Dev Biol. 1999. PMID: 10525340
Smad7 mediates apoptosis induced by transforming growth factor beta in prostatic carcinoma cells.
Landström M, Heldin NE, Bu S, Hermansson A, Itoh S, ten Dijke P, Heldin CH. Landström M, et al. Among authors: itoh s. Curr Biol. 2000 May 4;10(9):535-8. doi: 10.1016/s0960-9822(00)00470-x. Curr Biol. 2000. PMID: 10801443
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