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2,179 results
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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling.
Nakao A, Afrakhte M, Morén A, Nakayama T, Christian JL, Heuchel R, Itoh S, Kawabata M, Heldin NE, Heldin CH, ten Dijke P. Nakao A, et al. Among authors: itoh s. Nature. 1997 Oct 9;389(6651):631-5. doi: 10.1038/39369. Nature. 1997. PMID: 9335507
Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene.
Nakano N, Itoh S, Watanabe Y, Maeyama K, Itoh F, Kato M. Nakano N, et al. Among authors: itoh s, itoh f. J Biol Chem. 2010 Dec 3;285(49):38023-33. doi: 10.1074/jbc.M110.132209. Epub 2010 Sep 30. J Biol Chem. 2010. PMID: 20889500 Free PMC article.
TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling.
Watanabe Y, Itoh S, Goto T, Ohnishi E, Inamitsu M, Itoh F, Satoh K, Wiercinska E, Yang W, Shi L, Tanaka A, Nakano N, Mommaas AM, Shibuya H, Ten Dijke P, Kato M. Watanabe Y, et al. Among authors: itoh s, itoh f. Mol Cell. 2010 Jan 15;37(1):123-34. doi: 10.1016/j.molcel.2009.10.028. Mol Cell. 2010. PMID: 20129061
Negative regulation of TGF-beta receptor/Smad signal transduction.
Itoh S, ten Dijke P. Itoh S, et al. Curr Opin Cell Biol. 2007 Apr;19(2):176-84. doi: 10.1016/j.ceb.2007.02.015. Epub 2007 Feb 20. Curr Opin Cell Biol. 2007. PMID: 17317136 Review.
TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α.
Hamidi A, Song J, Thakur N, Itoh S, Marcusson A, Bergh A, Heldin CH, Landström M. Hamidi A, et al. Among authors: itoh s. Sci Signal. 2017 Jul 4;10(486):eaal4186. doi: 10.1126/scisignal.aal4186. Sci Signal. 2017. PMID: 28676490
TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.
Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S. Nakano N, et al. Among authors: itoh f, itoh s. J Biol Chem. 2017 Mar 10;292(10):4099-4112. doi: 10.1074/jbc.M116.769109. Epub 2017 Jan 23. J Biol Chem. 2017. PMID: 28115518 Free PMC article.
Smad7 and protein phosphatase 1alpha are critical determinants in the duration of TGF-beta/ALK1 signaling in endothelial cells.
Valdimarsdottir G, Goumans MJ, Itoh F, Itoh S, Heldin CH, ten Dijke P. Valdimarsdottir G, et al. Among authors: itoh f, itoh s. BMC Cell Biol. 2006 Mar 29;7:16. doi: 10.1186/1471-2121-7-16. BMC Cell Biol. 2006. PMID: 16571110 Free PMC article.
Synergy and antagonism between Notch and BMP receptor signaling pathways in endothelial cells.
Itoh F, Itoh S, Goumans MJ, Valdimarsdottir G, Iso T, Dotto GP, Hamamori Y, Kedes L, Kato M, ten Dijke Pt P. Itoh F, et al. Among authors: itoh s. EMBO J. 2004 Feb 11;23(3):541-51. doi: 10.1038/sj.emboj.7600065. Epub 2004 Jan 22. EMBO J. 2004. PMID: 14739937 Free PMC article.
Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling.
Goumans MJ, Valdimarsdottir G, Itoh S, Lebrin F, Larsson J, Mummery C, Karlsson S, ten Dijke P. Goumans MJ, et al. Among authors: itoh s. Mol Cell. 2003 Oct;12(4):817-28. doi: 10.1016/s1097-2765(03)00386-1. Mol Cell. 2003. PMID: 14580334
Elucidation of Smad requirement in transforming growth factor-beta type I receptor-induced responses.
Itoh S, Thorikay M, Kowanetz M, Moustakas A, Itoh F, Heldin CH, ten Dijke P. Itoh S, et al. Among authors: itoh f. J Biol Chem. 2003 Feb 7;278(6):3751-61. doi: 10.1074/jbc.M208258200. Epub 2002 Nov 22. J Biol Chem. 2003. PMID: 12446693
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