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The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates.
Iyer LM, Aravind L. Iyer LM, et al. BMC Genomics. 2002 Nov 27;3(1):33. doi: 10.1186/1471-2164-3-33. Epub 2002 Nov 27. BMC Genomics. 2002. PMID: 12456267 Free PMC article.
Extensive domain shuffling in transcription regulators of DNA viruses and implications for the origin of fungal APSES transcription factors.
Iyer LM, Koonin EV, Aravind L. Iyer LM, et al. Genome Biol. 2002;3(3):RESEARCH0012. doi: 10.1186/gb-2002-3-3-research0012. Epub 2002 Feb 13. Genome Biol. 2002. PMID: 11897024 Free PMC article.
Classification and evolutionary history of the single-strand annealing proteins, RecT, Redbeta, ERF and RAD52.
Iyer LM, Koonin EV, Aravind L. Iyer LM, et al. BMC Genomics. 2002 Mar 21;3:8. doi: 10.1186/1471-2164-3-8. Epub 2002 Mar 21. BMC Genomics. 2002. PMID: 11914131 Free PMC article.
The SWIRM domain: a conserved module found in chromosomal proteins points to novel chromatin-modifying activities.
Aravind L, Iyer LM. Aravind L, et al. Among authors: iyer lm. Genome Biol. 2002 Jul 24;3(8):RESEARCH0039. doi: 10.1186/gb-2002-3-8-research0039. Epub 2002 Jul 24. Genome Biol. 2002. PMID: 12186646 Free PMC article.
Detection of novel members, structure-function analysis and evolutionary classification of the 2H phosphoesterase superfamily.
Mazumder R, Iyer LM, Vasudevan S, Aravind L. Mazumder R, et al. Among authors: iyer lm. Nucleic Acids Res. 2002 Dec 1;30(23):5229-43. doi: 10.1093/nar/gkf645. Nucleic Acids Res. 2002. PMID: 12466548 Free PMC article.
Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases.
Iyer LM, Koonin EV, Aravind L. Iyer LM, et al. BMC Struct Biol. 2003 Jan 28;3:1. doi: 10.1186/1472-6807-3-1. Epub 2003 Jan 28. BMC Struct Biol. 2003. PMID: 12553882 Free PMC article.
Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins.
Iyer LM, Anantharaman V, Aravind L. Iyer LM, et al. BMC Genomics. 2003 Feb 3;4(1):5. doi: 10.1186/1471-2164-4-5. BMC Genomics. 2003. PMID: 12590654 Free PMC article.
Provenance of SET-domain histone methyltransferases through duplication of a simple structural unit.
Aravind L, Iyer LM. Aravind L, et al. Among authors: iyer lm. Cell Cycle. 2003 Jul-Aug;2(4):369-76. Cell Cycle. 2003. PMID: 12851491
The two faces of Alba: the evolutionary connection between proteins participating in chromatin structure and RNA metabolism.
Aravind L, Iyer LM, Anantharaman V. Aravind L, et al. Among authors: iyer lm. Genome Biol. 2003;4(10):R64. doi: 10.1186/gb-2003-4-10-r64. Epub 2003 Sep 8. Genome Biol. 2003. PMID: 14519199 Free PMC article.
Evolutionary history and higher order classification of AAA+ ATPases.
Iyer LM, Leipe DD, Koonin EV, Aravind L. Iyer LM, et al. J Struct Biol. 2004 Apr-May;146(1-2):11-31. doi: 10.1016/j.jsb.2003.10.010. J Struct Biol. 2004. PMID: 15037234
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