Iyer S - Search Results

1

Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.

Garcia EG, Iyer S, Garcia SP, Loontiens S, Sadreyev RI, Speleman F, Langenau DM. Garcia EG, et al. Among authors: iyer s. Leukemia. 2018 Aug;32(8):1860-1865. doi: 10.1038/s41375-018-0130-0. Epub 2018 Apr 18. Leukemia. 2018. PMID: 29749398 Free PMC article. No abstract available.

2

Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing.

Tang Q, Iyer S, Lobbardi R, Moore JC, Chen H, Lareau C, Hebert C, Shaw ML, Neftel C, Suva ML, Ceol CJ, Bernards A, Aryee M, Pinello L, Drummond IA, Langenau DM. Tang Q, et al. Among authors: iyer s. J Exp Med. 2017 Oct 2;214(10):2875-2887. doi: 10.1084/jem.20170976. Epub 2017 Sep 6. J Exp Med. 2017. PMID: 28878000 Free PMC article.

3

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.

Hayes MN, McCarthy K, Jin A, Oliveira ML, Iyer S, Garcia SP, Sindiri S, Gryder B, Motala Z, Nielsen GP, Borg JP, van de Rijn M, Malkin D, Khan J, Ignatius MS, Langenau DM. Hayes MN, et al. Among authors: iyer s. Cell Stem Cell. 2018 Mar 1;22(3):414-427.e6. doi: 10.1016/j.stem.2018.02.002. Cell Stem Cell. 2018. PMID: 29499154 Free PMC article.

4

Molecularly distinct models of zebrafish Myc-induced B cell leukemia.

Borga C, Foster CA, Iyer S, Garcia SP, Langenau DM, Frazer JK. Borga C, et al. Among authors: iyer s. Leukemia. 2019 Feb;33(2):559-562. doi: 10.1038/s41375-018-0328-1. Epub 2018 Dec 20. Leukemia. 2019. PMID: 30573774 Free PMC article. No abstract available.

5

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.

Grünewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK. Grünewald J, et al. Among authors: iyer s. Nature. 2019 May;569(7756):433-437. doi: 10.1038/s41586-019-1161-z. Epub 2019 Apr 17. Nature. 2019. PMID: 30995674 Free PMC article.

6

CRISPR DNA base editors with reduced RNA off-target and self-editing activities.

Grünewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK. Grünewald J, et al. Among authors: iyer s. Nat Biotechnol. 2019 Sep;37(9):1041-1048. doi: 10.1038/s41587-019-0236-6. Epub 2019 Sep 2. Nat Biotechnol. 2019. PMID: 31477922 Free PMC article.

7

A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.

Grünewald J, Zhou R, Lareau CA, Garcia SP, Iyer S, Miller BR, Langner LM, Hsu JY, Aryee MJ, Joung JK. Grünewald J, et al. Among authors: iyer s. Nat Biotechnol. 2020 Jul;38(7):861-864. doi: 10.1038/s41587-020-0535-y. Epub 2020 Jun 1. Nat Biotechnol. 2020. PMID: 32483364 Free PMC article.

8

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.

Garcia EG, Veloso A, Oliveira ML, Allen JR, Loontiens S, Brunson D, Do D, Yan C, Morris R, Iyer S, Garcia SP, Iftimia N, Van Loocke W, Matthijssens F, McCarthy K, Barata JT, Speleman F, Taghon T, Gutierrez A, Van Vlierberghe P, Haas W, Blackburn JS, Langenau DM. Garcia EG, et al. Among authors: iyer s. Leukemia. 2021 Mar;35(3):679-690. doi: 10.1038/s41375-020-0937-3. Epub 2020 Jun 30. Leukemia. 2021. PMID: 32606318 Free PMC article.

9

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells.

Kurt IC, Zhou R, Iyer S, Garcia SP, Miller BR, Langner LM, Grünewald J, Joung JK. Kurt IC, et al. Among authors: iyer s. Nat Biotechnol. 2021 Jan;39(1):41-46. doi: 10.1038/s41587-020-0609-x. Epub 2020 Jul 20. Nat Biotechnol. 2021. PMID: 32690971 Free PMC article.

10

The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.

Boulay G, Cironi L, Garcia SP, Rengarajan S, Xing YH, Lee L, Awad ME, Naigles B, Iyer S, Broye LC, Keskin T, Cauderay A, Fusco C, Letovanec I, Chebib I, Nielsen PG, Tercier S, Cherix S, Nguyen-Ngoc T, Cote G, Choy E, Provero P, Suvà ML, Rivera MN, Stamenkovic I, Riggi N. Boulay G, et al. Among authors: iyer s. Life Sci Alliance. 2020 Dec 23;4(2):e202000808. doi: 10.26508/lsa.202000808. Print 2021 Feb. Life Sci Alliance. 2020. PMID: 33361335 Free PMC article.

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