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Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death.
de Almagro MC, Goncharov T, Izrael-Tomasevic A, Duttler S, Kist M, Varfolomeev E, Wu X, Lee WP, Murray J, Webster JD, Yu K, Kirkpatrick DS, Newton K, Vucic D. de Almagro MC, et al. Among authors: izrael tomasevic a. Cell Death Differ. 2017 Jan;24(1):26-37. doi: 10.1038/cdd.2016.78. Epub 2016 Aug 12. Cell Death Differ. 2017. PMID: 27518435 Free PMC article.
Phosphorylation of NLRC4 is critical for inflammasome activation.
Qu Y, Misaghi S, Izrael-Tomasevic A, Newton K, Gilmour LL, Lamkanfi M, Louie S, Kayagaki N, Liu J, Kömüves L, Cupp JE, Arnott D, Monack D, Dixit VM. Qu Y, et al. Nature. 2012 Oct 25;490(7421):539-42. doi: 10.1038/nature11429. Epub 2012 Aug 12. Nature. 2012. PMID: 22885697
OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D. Goncharov T, et al. EMBO J. 2013 Apr 17;32(8):1103-14. doi: 10.1038/emboj.2013.62. Epub 2013 Mar 22. EMBO J. 2013. PMID: 23524849 Free PMC article.
NLRP3 recruitment by NLRC4 during Salmonella infection.
Qu Y, Misaghi S, Newton K, Maltzman A, Izrael-Tomasevic A, Arnott D, Dixit VM. Qu Y, et al. Among authors: izrael tomasevic a. J Exp Med. 2016 May 30;213(6):877-85. doi: 10.1084/jem.20132234. Epub 2016 May 2. J Exp Med. 2016. PMID: 27139490 Free PMC article.
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.
Goncharov T, Hedayati S, Mulvihill MM, Izrael-Tomasevic A, Zobel K, Jeet S, Fedorova AV, Eidenschenk C, deVoss J, Yu K, Shaw AS, Kirkpatrick DS, Fairbrother WJ, Deshayes K, Vucic D. Goncharov T, et al. Among authors: izrael tomasevic a. Mol Cell. 2018 Feb 15;69(4):551-565.e7. doi: 10.1016/j.molcel.2018.01.016. Mol Cell. 2018. PMID: 29452636 Free article.
Primary Amine Tethered Small Molecules Promote the Degradation of X-Linked Inhibitor of Apoptosis Protein.
den Besten W, Verma K, Yamazoe S, Blaquiere N, Phung W, Izrael-Tomasevic A, Mulvihill MM, Helgason E, Prakash S, Goncharov T, Vucic D, Dueber E, Fairbrother WJ, Wertz I, Yu K, Staben ST. den Besten W, et al. Among authors: izrael tomasevic a. J Am Chem Soc. 2021 Jul 21;143(28):10571-10575. doi: 10.1021/jacs.1c05269. Epub 2021 Jul 8. J Am Chem Soc. 2021. PMID: 34236858
19 results