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Activity and Selectivity Roadmap for C-N Electro-Coupling on MXenes.
Jiao Y, Li H, Jiao Y, Qiao SZ. Jiao Y, et al. J Am Chem Soc. 2023 Jul 19;145(28):15572-15580. doi: 10.1021/jacs.3c05171. Epub 2023 Jul 6. J Am Chem Soc. 2023. PMID: 37409766
Several potential catalysts were predicted with good C-N coupling performance, such as Ta(2)W(2)C(3). The candidate was then verified by DFT calculations. ...
Several potential catalysts were predicted with good C-N coupling performance, such as Ta(2)W(2)C(3). The candidate was then verified …
A photoactive self-healing carboxymethyl chitosan-based hydrogel for accelerated infected wound healing through simultaneously modulating multiple critical tissue repair factors.
Liu Y, Zhou A, Zhang Y, Tian Z, Cheng X, Gao Y, Zhou X, Wu X, Chen K, Ning X. Liu Y, et al. Int J Biol Macromol. 2023 Jul 1;242(Pt 1):124631. doi: 10.1016/j.ijbiomac.2023.124631. Epub 2023 Apr 27. Int J Biol Macromol. 2023. PMID: 37116834
Herein, a photoactive self-healing hydrogel (termed as Macropatch), composed of carboxymethyl chitosan (CMCS), tannic acid (TA) and graphitic carbon nitride g-C(3)N(4) (GCN), was developed to promote wound healing through simultaneously modulating pathological related fact …
Herein, a photoactive self-healing hydrogel (termed as Macropatch), composed of carboxymethyl chitosan (CMCS), tannic acid (TA) and g …
Detoxification of fluoroglucocorticoid by Acinetobacter pittii C3 via a novel defluorination pathway with hydrolysis, oxidation and reduction: Performance, genomic characteristics, and mechanism.
Xiang Y, Li S, Rene ER, Lun X, Zhang P, Ma W. Xiang Y, et al. J Hazard Mater. 2023 Jun 15;452:131302. doi: 10.1016/j.jhazmat.2023.131302. Epub 2023 Mar 29. J Hazard Mater. 2023. PMID: 37031670
Biological dehalogenation degradation was an important detoxification method for the ecotoxicity and teratogenic toxicity of fluorocorticosteroids (FGCs). The functional strain Acinetobacter pittii C3 can effectively biodegrade and defluorinate to 1 mg/L Triamcinolone acet …
Biological dehalogenation degradation was an important detoxification method for the ecotoxicity and teratogenic toxicity of fluorocorticost …
Pegcetacoplan controls hemolysis in complement inhibitor-naive patients with paroxysmal nocturnal hemoglobinuria.
Wong RSM, Navarro-Cabrera JR, Comia NS, Goh YT, Idrobo H, Kongkabpan D, Gómez-Almaguer D, Al-Adhami M, Ajayi T, Alvarenga P, Savage J, Deschatelets P, Francois C, Grossi F, Dumagay T. Wong RSM, et al. Blood Adv. 2023 Jun 13;7(11):2468-2478. doi: 10.1182/bloodadvances.2022009129. Blood Adv. 2023. PMID: 36848639 Free PMC article. Clinical Trial.
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease characterized by complement-mediated hemolysis. Pegcetacoplan is the first C3-targeted therapy approved for adults with PNH (United States), adults with PNH with inadequate response or intolerance to a C5 inhibito …
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disease characterized by complement-mediated hemolysis. Pegcetacoplan is the first C3
Fertility, early menopause and pregnancy outcomes of patients with Takayasu's arteritis.
Taghiyeva A, Kılıç L, Cagan M, Cagri Bolek E, Yardımcı GK, Ozyuncu O, Bilgen ŞA, Karadag O. Taghiyeva A, et al. Eur J Obstet Gynecol Reprod Biol. 2023 Apr;283:1-5. doi: 10.1016/j.ejogrb.2023.01.021. Epub 2023 Jan 21. Eur J Obstet Gynecol Reprod Biol. 2023. PMID: 36746073
This study aimed to evaluate fertility, early menopause and pregnancy outcomes of patients before and after TA diagnosis. In addition, pregnancy morbidities following TA diagnosis were analysed for each cluster. ...In total, there were 238 pregnancies in 83 female p …
This study aimed to evaluate fertility, early menopause and pregnancy outcomes of patients before and after TA diagnosis. In addition …
An interpretable machine learning approach based on DNN, SVR, Extra Tree, and XGBoost models for predicting daily pan evaporation.
El Bilali A, Abdeslam T, Ayoub N, Lamane H, Ezzaouini MA, Elbeltagi A. El Bilali A, et al. J Environ Manage. 2023 Feb 1;327:116890. doi: 10.1016/j.jenvman.2022.116890. Epub 2022 Nov 29. J Environ Manage. 2023. PMID: 36459782
Furthermore, the interpretability results of the ML models showed that the air temperature (Ta), solar radiation (Rs), followed by relative humidity (H) are the most important climate variables with inflection points of the Ta_median, Ta_mean, Rs_sum, H_mean, …
Furthermore, the interpretability results of the ML models showed that the air temperature (Ta), solar radiation (Rs), followed by re …
Response to Grosse and Gudgeon.
Lavelle TA, Feng X, Keisler M, Cohen JT, Neumann PJ, Prichard D, Schroeder BE, Salyakina D, Espinal PS, Weidner SB, Maron JL. Lavelle TA, et al. Genet Med. 2022 Dec;24(12):2597-2598. doi: 10.1016/j.gim.2022.08.031. Epub 2022 Sep 28. Genet Med. 2022. PMID: 36166002 Free article. No abstract available.
Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial.
de Latour RP, Szer J, Weitz IC, Röth A, Höchsmann B, Panse J, Usuki K, Griffin M, Kiladjian JJ, de Castro CM, Nishimori H, Ajayi T, Al-Adhami M, Deschatelets P, Francois C, Grossi F, Risitano AM, Hillmen P. de Latour RP, et al. Lancet Haematol. 2022 Sep;9(9):e648-e659. doi: 10.1016/S2352-3026(22)00210-1. Lancet Haematol. 2022. PMID: 36055332 Clinical Trial.
BACKGROUND: In the PEGASUS trial, the complement C3 inhibitor, pegcetacoplan, showed superiority to eculizumab in improving haematological outcomes in adult patients with paroxysmal nocturnal haemoglobinuria and suboptimal response to eculizumab at 16 weeks. ...
BACKGROUND: In the PEGASUS trial, the complement C3 inhibitor, pegcetacoplan, showed superiority to eculizumab in improving haematolo …
Upregulation of HIF-1α contributes to complement activation in transplantation-associated thrombotic microangiopathy.
Qi J, Pan T, You T, Tang Y, Chu T, Chen J, Fan Y, Hu S, Yang F, Ruan C, Wu D, Han Y. Qi J, et al. Br J Haematol. 2022 Nov;199(4):603-615. doi: 10.1111/bjh.18377. Epub 2022 Jul 21. Br J Haematol. 2022. PMID: 35864790
Complement activation is involved in the development of TA-TMA. However, the underlying mechanism is unclear. Therefore, 21 samples of TA-TMA and 1:1 matched controls were measured for hypoxia-inducible factor-1alpha (HIF-1alpha) and complement protein. ...In this s …
Complement activation is involved in the development of TA-TMA. However, the underlying mechanism is unclear. Therefore, 21 samples o …
117 results