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Thrombotic Microangiopathy as a Life-Threatening Complication of Long-Term Interferon Beta Therapy for Multiple Sclerosis: Clinical Phenotype and Response to Treatment-A Literature Review.
Allinovi M, Mazzierli T, Laudicina S, Pastò L, Portaccio E, Amato MP, Trivioli G. Allinovi M, et al. J Clin Med. 2024 Mar 11;13(6):1598. doi: 10.3390/jcm13061598. J Clin Med. 2024. PMID: 38541824 Review.
In only two patients, ADAMTS13 activity was reduced, while 27% had low C3 levels. However, none showed causative genetic mutations associated with development of atypical hemolytic uremic syndrome. ...
In only two patients, ADAMTS13 activity was reduced, while 27% had low C3 levels. However, none showed causative genetic mutations as …
Clinical and Epidemiological Study of IgA Nephropathy in the Bulgarian Population: Insights into Disease Presentation and Potential Biomarkers.
Kostadinova I, Lyubomirova M, Bogov B, Kurteva E, Kyurkchiev D, Todorov T. Kostadinova I, et al. J Pers Med. 2024 Feb 29;14(3):269. doi: 10.3390/jpm14030269. J Pers Med. 2024. PMID: 38541011

In fifty IgAN patients and 30 healthy controls, serum levels of Gd-IgA1, IgA, C3, BAFF, and APRIL using ELISA were examined. The results revealed significant differences in serum concentrations of Gd-IgA1 (p < 0.001), Gd-IgA1/IgA (p = 0.022), IgA (p = 0.014), and IgA/

In fifty IgAN patients and 30 healthy controls, serum levels of Gd-IgA1, IgA, C3, BAFF, and APRIL using ELISA were examined. The resu …
C3 concentrations can be normal in patients with C3 glomerulopathy secondary to C3 nephritic factor.
Anderson H, Van Voorthuizen M, O'Donnell J, Beck S. Anderson H, et al. J Clin Pathol. 2024 Mar 27:jcp-2023-209319. doi: 10.1136/jcp-2023-209319. Online ahead of print. J Clin Pathol. 2024. PMID: 38538072
C3 glomerulopathy (C3G) is a rare kidney disease caused by the glomerular deposition of C3 fragments secondary to alternative pathway complement dysregulation. ...Although C3 concentration can be normal in the presence of C3Nef, many laboratories will only pe
C3 glomerulopathy (C3G) is a rare kidney disease caused by the glomerular deposition of C3 fragments secondary to alternative
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