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Intrauterine exposure to mild analgesics is a risk factor for development of male reproductive disorders in human and rat.
Kristensen DM, Hass U, Lesné L, Lottrup G, Jacobsen PR, Desdoits-Lethimonier C, Boberg J, Petersen JH, Toppari J, Jensen TK, Brunak S, Skakkebaek NE, Nellemann C, Main KM, Jégou B, Leffers H. Kristensen DM, et al. Among authors: jegou b. Hum Reprod. 2011 Jan;26(1):235-44. doi: 10.1093/humrep/deq323. Epub 2010 Nov 8. Hum Reprod. 2011. PMID: 21059752
Prenatal exposure to paracetamol/acetaminophen and precursor aniline impairs masculinisation of male brain and behaviour.
Hay-Schmidt A, Finkielman OTE, Jensen BAH, Høgsbro CF, Bak Holm J, Johansen KH, Jensen TK, Andrade AM, Swan SH, Bornehag CG, Brunak S, Jegou B, Kristiansen K, Kristensen DM. Hay-Schmidt A, et al. Among authors: jegou b. Reproduction. 2017 Aug;154(2):145-152. doi: 10.1530/REP-17-0165. Epub 2017 May 30. Reproduction. 2017. PMID: 28559473 Free article.
Many putative endocrine disruptors inhibit prostaglandin synthesis.
Kristensen DM, Skalkam ML, Audouze K, Lesné L, Desdoits-Lethimonier C, Frederiksen H, Brunak S, Skakkebæk NE, Jégou B, Hansen JB, Junker S, Leffers H. Kristensen DM, et al. Among authors: jegou b. Environ Health Perspect. 2011 Apr;119(4):534-41. doi: 10.1289/ehp.1002635. Epub 2010 Nov 16. Environ Health Perspect. 2011. PMID: 21081300 Free PMC article.
Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism.
Kristensen DM, Desdoits-Lethimonier C, Mackey AL, Dalgaard MD, De Masi F, Munkbøl CH, Styrishave B, Antignac JP, Le Bizec B, Platel C, Hay-Schmidt A, Jensen TK, Lesné L, Mazaud-Guittot S, Kristiansen K, Brunak S, Kjaer M, Juul A, Jégou B. Kristensen DM, et al. Among authors: jegou b. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E715-E724. doi: 10.1073/pnas.1715035115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311296 Free PMC article. Clinical Trial.
Paracetamol use during pregnancy - a call for precautionary action.
Bauer AZ, Swan SH, Kriebel D, Liew Z, Taylor HS, Bornehag CG, Andrade AM, Olsen J, Jensen RH, Mitchell RT, Skakkebaek NE, Jégou B, Kristensen DM. Bauer AZ, et al. Among authors: jegou b. Nat Rev Endocrinol. 2021 Dec;17(12):757-766. doi: 10.1038/s41574-021-00553-7. Epub 2021 Sep 23. Nat Rev Endocrinol. 2021. PMID: 34556849 Free PMC article. Review.
Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility.
Holm JB, Mazaud-Guittot S, Danneskiold-Samsøe NB, Chalmey C, Jensen B, Nørregård MM, Hansen CH, Styrishave B, Svingen T, Vinggaard AM, Koch HM, Bowles J, Koopman P, Jégou B, Kristiansen K, Kristensen DM. Holm JB, et al. Among authors: jegou b. Toxicol Sci. 2016 Mar;150(1):178-89. doi: 10.1093/toxsci/kfv332. Epub 2016 Jan 5. Toxicol Sci. 2016. PMID: 26732887 Free article.
255 results