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A study on patients treated with polyacrylamide hydrogel injection for facial corrections.
Breiting V, Aasted A, Jørgensen A, Opitz P, Rosetzsky A. Breiting V, et al. Aesthetic Plast Surg. 2004 Jan-Feb;28(1):45-53. doi: 10.1007/s00266-003-3019-9. Epub 2004 May 3. Aesthetic Plast Surg. 2004. PMID: 15116275
A Danish/Swedish group of plastic surgeons with special interest in facial corrective surgery did a retrospective, systematic, pre-planned investigation of 104 patients treated at the center in Kiev. All data were entered into a pre-programmed database for da
A Danish/Swedish group of plastic surgeons with special interest in facial corrective surgery did a retrospective, systematic,
Protective effect of topical antibiotics in breast augmentation.
Pfeiffer P, Jørgensen S, Kristiansen TB, Jørgensen A, Hölmich LR. Pfeiffer P, et al. Plast Reconstr Surg. 2009 Aug;124(2):629-34. doi: 10.1097/PRS.0b013e3181addc68. Plast Reconstr Surg. 2009. PMID: 19644284
A retrospective analysis was performed to evaluate this effect. METHODS: The study participants included all women (n = 436) who underwent breast augmentation during two different time periods: 2000 to 2002 (n = 218) and 2005 to 2007 (n = 218). ...CONCLUSION: The authors'
A retrospective analysis was performed to evaluate this effect. METHODS: The study participants included all women (n = 436) who unde
The diagnosis of silicone breast-implant rupture: clinical findings compared with findings at magnetic resonance imaging.
Hölmich LR, Fryzek JP, Kjøller K, Breiting VB, Jørgensen A, Krag C, McLaughlin JK. Hölmich LR, et al. Ann Plast Surg. 2005 Jun;54(6):583-9. doi: 10.1097/01.sap.0000164470.76432.4f. Ann Plast Surg. 2005. PMID: 15900139
Fifty-five women with 109 implants underwent a breast examination either just before or shortly after an MRI examination. Twenty-four of 109 implants were clinically diagnosed with possible rupture or rupture. ...The positive predictive value of a clinical diagnosis …
Fifty-five women with 109 implants underwent a breast examination either just before or shortly after an MRI examination. Twenty-four …
Long-term effects of polyacrylamide hydrogel on human breast tissue.
Christensen LH, Breiting VB, Aasted A, Jørgensen A, Kebuladze I. Christensen LH, et al. Plast Reconstr Surg. 2003 May;111(6):1883-90. doi: 10.1097/01.PRS.0000056873.87165.5A. Plast Reconstr Surg. 2003. PMID: 12711948
The gel presented itself as a dark violet, homogenous mass with a rounded or ragged outline in large or medium-size deposits and as elongated strands, which mimicked the extracellular matrix, in small deposits. ...However, to determine safety with more certainty, …
The gel presented itself as a dark violet, homogenous mass with a rounded or ragged outline in large or medium-size deposits a …
Multivariate data analysis as a fast tool in evaluation of solid state phenomena.
Jørgensen AC, Miroshnyk I, Karjalainen M, Jouppila K, Siiriä S, Antikainen O, Rantanen J. Jørgensen AC, et al. J Pharm Sci. 2006 Apr;95(4):906-16. doi: 10.1002/jps.20573. J Pharm Sci. 2006. PMID: 16493589
A thorough understanding of solid state properties is of growing importance. It is often necessary to apply multiple techniques offering complementary information to fully understand the solid state behavior of a given compound and the relations between various poly
A thorough understanding of solid state properties is of growing importance. It is often necessary to apply multiple techniques offer
Novel identification of pseudopolymorphic changes of theophylline during wet granulation using near infrared spectroscopy.
Räsänen E, Rantanen J, Jørgensen A, Karjalainen M, Paakkari T, Yliruusi J. Räsänen E, et al. J Pharm Sci. 2001 Mar;90(3):389-96. doi: 10.1002/1520-6017(200103)90:3<389::aid-jps13>3.0.co;2-9. J Pharm Sci. 2001. PMID: 11170031
At a low level of granulation liquid (0.3 mol of water per mole of anhydrous theophylline), water absorption maxima in the NIR region occurred first at around 1475 and 1970 nm. ...NIR spectroscopy was able to detect different states of water molecules during the wet granul …
At a low level of granulation liquid (0.3 mol of water per mole of anhydrous theophylline), water absorption maxima in the NIR region …
Process analysis of fluidized bed granulation.
Rantanen J, Jørgensen A, Räsänen E, Luukkonen P, Airaksinen S, Raiman J, Hänninen K, Antikainen O, Yliruusi J. Rantanen J, et al. AAPS PharmSciTech. 2001 Oct 17;2(4):21. doi: 10.1208/pt020421. AAPS PharmSciTech. 2001. PMID: 14727858 Free PMC article.
The granulation process was analyzed using an automated granulator and optimization of the verapamil hydrochloride formulation was performed using a mixture design. ...NIR moisture measurement combined with temperature and humidity measurements provides a tool for t …
The granulation process was analyzed using an automated granulator and optimization of the verapamil hydrochloride formulation was performed …
The influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG).
Baldursdottir S, Tian F, Santacruz BG, Jørgensen AC, Rantanen J. Baldursdottir S, et al. Pharm Dev Technol. 2012 Mar-Apr;17(2):195-203. doi: 10.3109/10837450.2010.531733. Epub 2010 Nov 15. Pharm Dev Technol. 2012. PMID: 21077753
OBJECTIVES: To investigate the influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG), commonly used as a pharmaceutical excipient. ...
OBJECTIVES: To investigate the influence of thermal history on the physical behavior of poly(ethylene glycol) (PEG), commonly used as a
An insight into water of crystallization during processing using vibrational spectroscopy.
Jørgensen AC, Strachan CJ, Pöllänen KH, Koradia V, Tian F, Rantanen J. Jørgensen AC, et al. J Pharm Sci. 2009 Nov;98(11):3903-32. doi: 10.1002/jps.21735. J Pharm Sci. 2009. PMID: 19670461 Review.
The review begins with a general section on hydrates, followed by considerations on the impact of these on drug products and a description of transformation mechanisms of hydrates. Moreover, a general introduction is given for the spectroscopic techniques tog …
The review begins with a general section on hydrates, followed by considerations on the impact of these on drug products and a
Humid storage conditions increase the dissolution rate of diazepam from solid dispersions prepared by melt agglomeration.
Jørgensen AC, Torstenson AS. Jørgensen AC, et al. Pharm Dev Technol. 2008;13(3):187-95. doi: 10.1080/10837450801949384. Pharm Dev Technol. 2008. PMID: 18484487
The purpose of this study is to investigate the effect of cooling mode and storage conditions on the dissolution rate of a solid dispersion prepared by melt agglomeration. ...The processing and storage conditions were shown to have a complex interplay....
The purpose of this study is to investigate the effect of cooling mode and storage conditions on the dissolution rate of a solid disp …
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