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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1977 1
1983 1
1986 1
1987 1
1988 1
1991 1
1992 3
1993 4
1996 2
1997 2
1998 4
2000 5
2002 1
2003 1
2005 9
2006 18
2007 12
2008 15
2009 14
2010 21
2011 25
2012 42
2013 62
2014 60
2015 50
2016 50
2017 51
2018 33
2019 35
2020 34
2021 34
2022 18
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542 results
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Page 1
Natalizumab in Multiple Sclerosis: Long-Term Management.
Clerico M, Artusi CA, Liberto AD, Rolla S, Bardina V, Barbero P, Mercanti SF, Durelli L. Clerico M, et al. Int J Mol Sci. 2017 Apr 29;18(5):940. doi: 10.3390/ijms18050940. Int J Mol Sci. 2017. PMID: 28468254 Free PMC article. Review.
Natalizumab is a monoclonal antibody highly effective in the treatment of relapsing remitting multiple sclerosis (RRMS) patients. Despite its effectiveness, there are growing concerns regarding the risk of progressive multifocal leukoencephalopathy (PML), a brain in …
Natalizumab is a monoclonal antibody highly effective in the treatment of relapsing remitting multiple sclerosis (RRMS) patien …
Progressive multifocal leukoencephalopathy and the spectrum of JC virus-related disease.
Cortese I, Reich DS, Nath A. Cortese I, et al. Nat Rev Neurol. 2021 Jan;17(1):37-51. doi: 10.1038/s41582-020-00427-y. Epub 2020 Nov 20. Nat Rev Neurol. 2021. PMID: 33219338 Free PMC article. Review.
Progressive multifocal leukoencephalopathy (PML) is a devastating CNS infection caused by JC virus (JCV), a polyomavirus that commonly establishes persistent, asymptomatic infection in the general population. ...Antiretroviral therapies greatly reduce the ris …
Progressive multifocal leukoencephalopathy (PML) is a devastating CNS infection caused by JC virus (JCV), a polyomavirus
Disease-modifying therapies and progressive multifocal leukoencephalopathy in multiple sclerosis: A systematic review and meta-analysis.
Sriwastava S, Kataria S, Srivastava S, Kazemlou S, Gao S, Wen S, Saber H, Tripathi R, Sheikh Z, Peterson S, Gwinn R, Bernitsas E. Sriwastava S, et al. J Neuroimmunol. 2021 Nov 15;360:577721. doi: 10.1016/j.jneuroim.2021.577721. Epub 2021 Sep 15. J Neuroimmunol. 2021. PMID: 34547511
Background High efficacy disease modifying therapies (DMT) in the management of Multiple Sclerosis (MS) have a favorable effect on relapse rate and disability progression; however, they can expose patients to significant risks, such as progressive multifocal leukoen …
Background High efficacy disease modifying therapies (DMT) in the management of Multiple Sclerosis (MS) have a favorable effec …
Biomarkers in multiple sclerosis.
Housley WJ, Pitt D, Hafler DA. Housley WJ, et al. Clin Immunol. 2015 Nov;161(1):51-8. doi: 10.1016/j.clim.2015.06.015. Epub 2015 Jul 2. Clin Immunol. 2015. PMID: 26143623 Review.
Substantial effort has been made over the last six decades to identify biomarkers for multiple sclerosis that can improve disease diagnosis, predict disease progression, and improve clinical outcomes. ...We start by discussing biomarkers currently in clinical use in …
Substantial effort has been made over the last six decades to identify biomarkers for multiple sclerosis that can improve dise …
Progressive multifocal leukoencephalopathy and other disorders caused by JC virus: clinical features and pathogenesis.
Tan CS, Koralnik IJ. Tan CS, et al. Lancet Neurol. 2010 Apr;9(4):425-37. doi: 10.1016/S1474-4422(10)70040-5. Lancet Neurol. 2010. PMID: 20298966 Free PMC article. Review.
Additionally, the JC virus can also lead to novel neurological disorders such as JC virus granule cell neuronopathy and JC virus encephalopathy, and might also cause meningitis. The increasingly diverse populations at risk and the recent …
Additionally, the JC virus can also lead to novel neurological disorders such as JC virus granule cell neuronopa …
Specific antibodies reacting to JC polyomavirus capsid protein mimotopes in sera from multiple sclerosis and other neurological diseases-affected patients.
Mazzoni E, Bononi I, Pietrobon S, Torreggiani E, Rossini M, Pugliatti M, Casetta I, Castellazzi M, Granieri E, Guerra G, Martini F, Tognon M. Mazzoni E, et al. J Cell Physiol. 2020 Jul;235(7-8):5847-5855. doi: 10.1002/jcp.29533. Epub 2020 Feb 3. J Cell Physiol. 2020. PMID: 32012272
JC (JC polyomavirus [JCPyV]), BK (BKPyV), and simian virus 40 (SV40) neurotropic polyomavirus footprints have been detected in brain tissue specimens and samples from patients affected by different neurological diseases. ...Our study indicates t
JC (JC polyomavirus [JCPyV]), BK (BKPyV), and simian virus 40 (SV40) neurotropic polyomavirus footprints
Risk of natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: a retrospective analysis of data from four clinical studies.
Ho PR, Koendgen H, Campbell N, Haddock B, Richman S, Chang I. Ho PR, et al. Lancet Neurol. 2017 Nov;16(11):925-933. doi: 10.1016/S1474-4422(17)30282-X. Epub 2017 Sep 29. Lancet Neurol. 2017. PMID: 28969984
BACKGROUND: Previous estimates of risk of progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis receiving natalizumab were stratified by three risk factors: anti-John Cunningham virus (JCV) antibodies in serum, previous immunosu …
BACKGROUND: Previous estimates of risk of progressive multifocal leukoencephalopathy (PML) in patients with multiple sclerosis
The biology of JC polyomavirus.
Assetta B, Atwood WJ. Assetta B, et al. Biol Chem. 2017 Jul 26;398(8):839-855. doi: 10.1515/hsz-2016-0345. Biol Chem. 2017. PMID: 28493815 Review.
JC polyomavirus (JCPyV) is the causative agent of a fatal central nervous system demyelinating disease known as progressive multifocal leukoencephalopathy (PML). PML occurs in people with underlying immunodeficiency or in individuals being treated with potent immuno
JC polyomavirus (JCPyV) is the causative agent of a fatal central nervous system demyelinating disease known as progressive mu
JC polyomavirus, progressive multifocal leukoencephalopathy.
L'Honneur AS, Rozenberg F. L'Honneur AS, et al. Virologie (Montrouge). 2016 Jun 1;20(3):174-187. doi: 10.1684/vir.2016.0653. Virologie (Montrouge). 2016. PMID: 33065896 English.
JC virus (JCV) is an ubiquitous human polyomavirus which causes persistent infections. ...PML cases have recently increased in patients receiving monoclonal antibody therapies - in particular multiple sclerosis patients treated with natalizumab
JC virus (JCV) is an ubiquitous human polyomavirus which causes persistent infections. ...PML cases have recently incre
Progressive Multifocal Leukoencephalopathy.
Saji AM, Gupta V. Saji AM, et al. 2022 Jul 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. 2022 Jul 11. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32809419 Free Books & Documents.
Progressive multifocal leukoencephalopathy (PML) is a neurological condition caused by the JC virus. PML is a demyelinating disease preferentially affecting the central nervous system. ...Certain monoclonal antibodies, specifically, natalizumab used in the treatment …
Progressive multifocal leukoencephalopathy (PML) is a neurological condition caused by the JC virus. PML is a demyelinating di …
542 results