JOINT PAIN AND PHOTOBIOMODULATION - Search Results

Year	Number of Results
1998	1
2000	1
2003	5
2004	2
2005	5
2006	6
2007	6
2008	7
2009	6
2010	12
2011	9
2012	17
2013	17
2014	18
2015	17
2016	10
2017	17
2018	21
2019	23
2020	26
2021	24
2022	26
2023	27
2024	16

1

Comparative efficacy of low-Level laser and TENS in the symptomatic relief of temporomandibular joint disorders: A randomized clinical trial.

Chellappa D, Thirupathy M. Chellappa D, et al. Indian J Dent Res. 2020 Jan-Feb;31(1):42-47. doi: 10.4103/ijdr.IJDR_735_18. Indian J Dent Res. 2020. PMID: 32246680 Free article. Clinical Trial.

OBJECTIVES: Therefore, the aim of this study was to compare the effectiveness of transcutaneous electric nerve stimulation (TENS) and low-level laser therapy for the treatment of patients with TMD. Materials and Methods: The clinical trial was performed with …

OBJECTIVES: Therefore, the aim of this study was to compare the effectiveness of transcutaneous electric nerve stimulation (TENS) and low …

2

Effects of low-level and high-intensity laser therapy as adjunctive to rehabilitation exercise on pain, stiffness and function in knee osteoarthritis: a systematic review and meta-analysis.

Ahmad MA, A Hamid MS, Yusof A. Ahmad MA, et al. Physiotherapy. 2022 Mar;114:85-95. doi: 10.1016/j.physio.2021.03.011. Epub 2021 Mar 26. Physiotherapy. 2022. PMID: 34654554 Review.

BACKGROUND: When treating knee osteoarthritis (KOA), rehabilitation exercise is often combined with low-level (LLLT) or high-intensity laser therapy (HILT). However, the effectiveness of these combinations is still uncertain. ...Based on an indirect compariso …

BACKGROUND: When treating knee osteoarthritis (KOA), rehabilitation exercise is often combined with low-level (LLLT) or high-i …

3

The Mechanisms and Efficacy of Photobiomodulation Therapy for Arthritis: A Comprehensive Review.

Zhang R, Qu J. Zhang R, et al. Int J Mol Sci. 2023 Sep 19;24(18):14293. doi: 10.3390/ijms241814293. Int J Mol Sci. 2023. PMID: 37762594 Free PMC article. Review.

Rheumatoid arthritis (RA) and osteoarthritis (OA) have a significant impact on the quality of life of patients around the world, causing significant pain and disability. Furthermore, the drugs used to treat these conditions frequently have side effects that add to the pati …

Rheumatoid arthritis (RA) and osteoarthritis (OA) have a significant impact on the quality of life of patients around the world, causing sig …

4

Lateral epicondylitis: a review of pathology and management.

Ahmad Z, Siddiqui N, Malik SS, Abdus-Samee M, Tytherleigh-Strong G, Rushton N. Ahmad Z, et al. Bone Joint J. 2013 Sep;95-B(9):1158-64. doi: 10.1302/0301-620X.95B9.29285. Bone Joint J. 2013. PMID: 23997125 Free article. Review.

5

Diagnosis and treatment of osteoarthritis.

Rychel JK. Rychel JK. Top Companion Anim Med. 2010 Feb;25(1):20-5. doi: 10.1053/j.tcam.2009.10.005. Top Companion Anim Med. 2010. PMID: 20188335 Review.

Although OA cannot be cured, long-term management of the disease can be very rewarding for the veterinary medical team as well as pet owners. Managing pain with pain medications is an essential first step. There are a wealth of pain medications available, inc …

Although OA cannot be cured, long-term management of the disease can be very rewarding for the veterinary medical team as well as pet owners …

6

Acne fulminans.

Dall'oglio F, Puglisi DF, Nasca MR, Micali G. Dall'oglio F, et al. G Ital Dermatol Venereol. 2020 Dec;155(6):711-718. doi: 10.23736/S0392-0488.20.06711-5. Epub 2020 Oct 21. G Ital Dermatol Venereol. 2020. PMID: 33084268 Free article. Review.

7

Electrotherapy modalities for rotator cuff disease.

Page MJ, Green S, Mrocki MA, Surace SJ, Deitch J, McBain B, Lyttle N, Buchbinder R. Page MJ, et al. Cochrane Database Syst Rev. 2016 Jun 10;2016(6):CD012225. doi: 10.1002/14651858.CD012225. Cochrane Database Syst Rev. 2016. PMID: 27283591 Free PMC article. Review.

Examples include therapeutic ultrasound, low-level laser therapy (LLLT), transcutaneous electrical nerve stimulation (TENS), and pulsed electromagnetic field therapy (PEMF). These modalities are usually delivered as components of a physical therapy …

Examples include therapeutic ultrasound, low-level laser therapy (LLLT), transcutaneous electrical nerve stimulation (T …

8

Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: systematic review and meta-analysis of randomised placebo-controlled trials.

Stausholm MB, Naterstad IF, Joensen J, Lopes-Martins RÁB, Sæbø H, Lund H, Fersum KV, Bjordal JM. Stausholm MB, et al. BMJ Open. 2019 Oct 28;9(10):e031142. doi: 10.1136/bmjopen-2019-031142. BMJ Open. 2019. PMID: 31662383 Free PMC article.

OBJECTIVES: Low-level laser therapy (LLLT) is not recommended in major knee osteoarthritis (KOA) treatment guidelines. ...The subgroup analysis revealed that pain was significantly reduced by the recommended LLLT doses compared with placebo at the end …

OBJECTIVES: Low-level laser therapy (LLLT) is not recommended in major knee osteoarthritis (KOA) treatment guidelines. …

9

Electrotherapy modalities for adhesive capsulitis (frozen shoulder).

Page MJ, Green S, Kramer S, Johnston RV, McBain B, Buchbinder R. Page MJ, et al. Cochrane Database Syst Rev. 2014 Oct 1;2014(10):CD011324. doi: 10.1002/14651858.CD011324. Cochrane Database Syst Rev. 2014. PMID: 25271097 Free PMC article. Review.

Electrotherapy modalities, which aim to reduce pain and improve function via an increase in energy (electrical, sound, light, thermal) into the body, are often delivered as components of a physical therapy intervention. ...Four trials reported using an adequa …

Electrotherapy modalities, which aim to reduce pain and improve function via an increase in energy (electrical, sound, light, …

10

Efficacy of high-intensity laser therapy in patients with adhesive capsulitis: a sham-controlled randomized controlled trial.

Atan T, Bahar-Ozdemir Y. Atan T, et al. Lasers Med Sci. 2021 Feb;36(1):207-217. doi: 10.1007/s10103-020-03121-z. Epub 2020 Aug 18. Lasers Med Sci. 2021. PMID: 32808147 Clinical Trial.

The purpose of the study is to evaluate the effects of high-intensity laser therapy (HILT) on pain, disability, and quality of life in patients with adhesive capsulitis. ...The primary outcome measure was the visual analogue scale for pain (Visual Analog Scal …

The purpose of the study is to evaluate the effects of high-intensity laser therapy (HILT) on pain, disability, and quality of …

11

The Effect of Photobiomodulation on Temporomandibular Pain and Functions in Patients With Temporomandibular Disorders: An Updated Systematic Review of the Current Randomized Controlled Trials.

Farshidfar N, Farzinnia G, Samiraninezhad N, Assar S, Firoozi P, Rezazadeh F, Hakimiha N. Farshidfar N, et al. J Lasers Med Sci. 2023 Aug 5;14:e24. doi: 10.34172/jlms.2023.24. eCollection 2023. J Lasers Med Sci. 2023. PMID: 37744015 Free PMC article. Review.

Photobiomodulation therapy (PBMT) is a conservative way to improve function and reduce symptoms in TMD patients. ...All included studies except one provided information on pain intensity; 27 studies showed a reduction in pain intensity in PBMT groups c …

Photobiomodulation therapy (PBMT) is a conservative way to improve function and reduce symptoms in TMD patients. ...All includ …

12

Low-level laser therapy in temporomandibular joint disorders: a systematic review.

Ahmad SA, Hasan S, Saeed S, Khan A, Khan M. Ahmad SA, et al. J Med Life. 2021 Mar-Apr;14(2):148-164. doi: 10.25122/jml-2020-0169. J Med Life. 2021. PMID: 34104237 Free PMC article.

Myofascial pain, internal derangement of the joint, and degenerative joint diseases constitute the majority of TMDs. TMDs usually have a multifactorial etiology, and treatment modalities range from conservative therapies to surgical interventions. Low- …

Myofascial pain, internal derangement of the joint, and degenerative joint diseases constitute the majority of TMDs. TM …

13

Photobiomodulation reduces neuropathic pain after spinal cord injury by downregulating CXCL10 expression.

Zhang Z, Zhu Z, Zuo X, Wang X, Ju C, Liang Z, Li K, Zhang J, Luo L, Ma Y, Song Z, Li X, Li P, Quan H, Huang P, Yao Z, Yang N, Zhou J, Kou Z, Chen B, Ding T, Wang Z, Hu X. Zhang Z, et al. CNS Neurosci Ther. 2023 Dec;29(12):3995-4017. doi: 10.1111/cns.14325. Epub 2023 Jul 20. CNS Neurosci Ther. 2023. PMID: 37475184 Free PMC article.

BACKGROUND: Many studies have recently highlighted the role of photobiomodulation (PBM) in neuropathic pain (NP) relief after spinal cord injury (SCI), suggesting that it may be an effective way to relieve NP after SCI. ...Taken together, our study provides evidence …

BACKGROUND: Many studies have recently highlighted the role of photobiomodulation (PBM) in neuropathic pain (NP) relief after …

14

The efficacy of low-level laser therapy for shoulder tendinopathy: a systematic review and meta-analysis of randomized controlled trials.

Haslerud S, Magnussen LH, Joensen J, Lopes-Martins RA, Bjordal JM. Haslerud S, et al. Physiother Res Int. 2015 Jun;20(2):108-25. doi: 10.1002/pri.1606. Epub 2014 Dec 2. Physiother Res Int. 2015. PMID: 25450903 Review.

BACKGROUND AND PURPOSE: Low-level laser therapy (LLLT) is proposed as a treatment for tendinopathies. This is the first systematic review focusing solely on LLLT treatment effects in shoulder tendinopathy. ...RESULTS: Seventeen randomized controlled trials (R …

BACKGROUND AND PURPOSE: Low-level laser therapy (LLLT) is proposed as a treatment for tendinopathies. This is the first …

15

Effectiveness of high-intensity laser therapy in the treatment of patients with frozen shoulder: a systematic review and meta-analysis.

de la Barra Ortiz HA, Parizotto N, Arias M, Liebano R. de la Barra Ortiz HA, et al. Lasers Med Sci. 2023 Nov 20;38(1):266. doi: 10.1007/s10103-023-03901-3. Lasers Med Sci. 2023. PMID: 37981583 Review.

The inclusion criteria encompassed RCTs comparing HILT with other physical therapy interventions in frozen patients with frozen shoulders, with or without sham HILT, assessing pain intensity, shoulder ROM, and disability outcomes. ...PI and disability changes were g …

The inclusion criteria encompassed RCTs comparing HILT with other physical therapy interventions in frozen patients with frozen shoul …

16

Physical therapy interventions used to treat individuals with biceps tendinopathy: a scoping review.

McDevitt AW, Young JL, Cleland JA, Hiefield P, Snodgrass SJ. McDevitt AW, et al. Braz J Phys Ther. 2024 Jan-Feb;28(1):100586. doi: 10.1016/j.bjpt.2023.100586. Epub 2023 Dec 27. Braz J Phys Ther. 2024. PMID: 38219522 Free PMC article. Review.

BACKGROUND: Shoulder pain related to pathology of the long head of the biceps tendon (LHBT) can be debilitating. ...Interventions used to treat LHBT tendinopathy identified in quantitative studies included: extracorporeal shock wave therapy, polarized light, …

BACKGROUND: Shoulder pain related to pathology of the long head of the biceps tendon (LHBT) can be debilitating. ...Interventions use …

17

Photobiomodulation Therapy for Myofascial Pain in Temporomandibular Joint Dysfunction: A Double-Blinded Randomized Clinical Trial.

Nadershah M, Abdel-Alim HM, Bayoumi AM, Jan AM, Elatrouni A, Jadu FM. Nadershah M, et al. J Maxillofac Oral Surg. 2020 Mar;19(1):93-97. doi: 10.1007/s12663-019-01222-z. Epub 2019 Apr 2. J Maxillofac Oral Surg. 2020. PMID: 31988570 Free PMC article.

Photobiomodulation therapy has been suggested for management of TMD, despite the lack of understanding of its exact mechanism. ...CONCLUSION: Photobiomodulation therapy proved to be an effective short-term therapeutic modality for myofascial TMD pai …

Photobiomodulation therapy has been suggested for management of TMD, despite the lack of understanding of its exact mechanism. …

18

Photobiomodulation Therapy Partially Restores Cartilage Integrity and Reduces Chronic Pain Behavior in a Rat Model of Osteoarthritis: Involvement of Spinal Glial Modulation.

Balbinot G, Schuch CP, Nascimento PSD, Lanferdini FJ, Casanova M, Baroni BM, Vaz MA. Balbinot G, et al. Cartilage. 2021 Dec;13(2_suppl):1309S-1321S. doi: 10.1177/1947603519876338. Epub 2019 Sep 30. Cartilage. 2021. PMID: 31569995 Free PMC article.

This study investigated the efficacy of photobiomodulation therapy (PBMT) on cartilage integrity and central pain biomarkers in adult male Wistar rats. ...Furthermore, we analyzed the principal components related to pain-like behavior and cartilage int …

This study investigated the efficacy of photobiomodulation therapy (PBMT) on cartilage integrity and central pain bioma …

19

Combined effect of laser acupuncture and electroacupuncture in knee osteoarthritis patients: A protocol for a randomized controlled trial.

Wu SY, Lin CH, Chang NJ, Hu WL, Hung YC, Tsao Y, Kuo CA. Wu SY, et al. Medicine (Baltimore). 2020 Mar;99(12):e19541. doi: 10.1097/MD.0000000000019541. Medicine (Baltimore). 2020. PMID: 32195960 Free PMC article. Clinical Trial.

BACKGROUND: Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead to disability and is often associated with cardiovascular disease, poor quality of life, and mortality. ...Electroacupuncture (EA) and laser …

BACKGROUND: Knee osteoarthritis (KOA) is a common degenerative joint disorder that affects 250 million people globally. KOA can lead …

20

Photobiomodulation Therapy on the Palliative Care of Temporomandibular Disorder and Orofacial/Cervical Skull Pain: Preliminary Results from a Randomized Controlled Clinical Trial.

Carvalho FR, Barros RQ, Gonçalves AS, Muragaki SP, Pedroni ACF, Oliveira KDCM, Freitas PM. Carvalho FR, et al. Healthcare (Basel). 2023 Sep 18;11(18):2574. doi: 10.3390/healthcare11182574. Healthcare (Basel). 2023. PMID: 37761771 Free PMC article.

The photobiomodulation therapy (PBMT) has been reported as a promising treatment in the management of these symptoms. ...According to the RDC/TMD, maximum mouth opening (MMO) and pain in the orofacial/cervical muscles and temporomandibular joint (TMJ) …

The photobiomodulation therapy (PBMT) has been reported as a promising treatment in the management of these symptoms. ...Accor …

21

Rehabilitation of the Canine Forelimb.

Brown JA, Tomlinson J. Brown JA, et al. Vet Clin North Am Small Anim Pract. 2021 Mar;51(2):401-420. doi: 10.1016/j.cvsm.2020.12.005. Vet Clin North Am Small Anim Pract. 2021. PMID: 33558014 Review.

The goal of rehabilitation is to restore function and mobility and reduce pain associated with chronic disease. In human medicine, physical therapy is standard of care for acute and chronic injuries and an integral component of postoperative recovery. ...When develo …

The goal of rehabilitation is to restore function and mobility and reduce pain associated with chronic disease. In human medicine, ph …

22

Current advances of photobiomodulation therapy in treating knee osteoarthritis.

Zhang Y, Ji Q. Zhang Y, et al. Front Cell Dev Biol. 2023 Nov 16;11:1286025. doi: 10.3389/fcell.2023.1286025. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38033853 Free PMC article. Review.

It is one of the most prevalent degenerative diseases in the elderly. KOA usually results in chronic joint pain, physical impairment even disability bringing a huge socioeconomic burden. ...There is a pressing need for explorations and developments of new effective …

It is one of the most prevalent degenerative diseases in the elderly. KOA usually results in chronic joint pain, physical impa …

23

Analysis of pain relief and functional recovery in patients with rotator cuff tendinopathy through therapeutic ultrasound and photobiomodulation therapy: a comparative study.

Martins JPS, de Lima CJ, Fernandes AB, Alves LP, Neto OP, Villaverde AB. Martins JPS, et al. Lasers Med Sci. 2022 Oct;37(8):3155-3167. doi: 10.1007/s10103-022-03584-2. Epub 2022 Jun 1. Lasers Med Sci. 2022. PMID: 35648258

This study aimed to compare shoulder tendinopathy treatment with therapeutic ultrasound combined with LED photobiomodulation therapy using LED-infrared (850 nm) or LED-red (640 nm). The study assessed 75 patients, aged 45 to 70 years, distributed into five experimen …

This study aimed to compare shoulder tendinopathy treatment with therapeutic ultrasound combined with LED photobiomodulation thera …

24

Macrophage polarization in osteoarthritis progression: a promising therapeutic target.

Zhang Y, Ji Q. Zhang Y, et al. Front Cell Dev Biol. 2023 Oct 26;11:1269724. doi: 10.3389/fcell.2023.1269724. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37954210 Free PMC article. Review.

Unfortunately, there is currently no effective therapy to delay its progression and the underlying mechanisms of OA require further exploration. ...In this review, we summarized the involvements of polarized macrophages in synovitis, cartilage degradation, osteophyte forma …

Unfortunately, there is currently no effective therapy to delay its progression and the underlying mechanisms of OA require further e …

25

Application of photobiomodulation for chronic pain-related TMD on pain points versus pre-established points: Randomized clinical trial.

Furquim LR, Mélo AM, Barbosa AFS, Olivato OP, Silva-Sousa YTC, Leite-Panissi CRA, Magri LV. Furquim LR, et al. J Photochem Photobiol B. 2023 Jan;238:112612. doi: 10.1016/j.jphotobiol.2022.112612. Epub 2022 Nov 26. J Photochem Photobiol B. 2023. PMID: 36459910 Clinical Trial.

Photobiomodulation therapy (PTB) is a therapeutic possibility for temporomandibular disorders (TMD), but its effectiveness and protocols for use remain controversial. ...Pain intensity evaluation (last days) also showed that application at the pain poi …

Photobiomodulation therapy (PTB) is a therapeutic possibility for temporomandibular disorders (TMD), but its effectiveness and …

26

Photobiomodulation therapy (PBMT) on acute pain and inflammation in patients who underwent total hip arthroplasty-a randomized, triple-blind, placebo-controlled clinical trial.

Langella LG, Casalechi HL, Tomazoni SS, Johnson DS, Albertini R, Pallotta RC, Marcos RL, de Carvalho PTC, Leal-Junior ECP. Langella LG, et al. Lasers Med Sci. 2018 Dec;33(9):1933-1940. doi: 10.1007/s10103-018-2558-x. Epub 2018 Jun 16. Lasers Med Sci. 2018. PMID: 29909435 Clinical Trial.

Surgical procedures induced tissue trauma and incite an immune response. Photobiomodulation therapy (PBMt) using low-level laser therapy (LLLT) and/or light-emitting diode therapy (LEDT) has proven effective in tissue repair by mod …

Surgical procedures induced tissue trauma and incite an immune response. Photobiomodulation therapy (PBMt) using low- …

27

The Effects of Photobiomodulation on Knee Function, Pain, and Exercise Tolerance in Older Adults: A Meta-analysis of Randomized Controlled Trials.

Li BM, Zhang CK, He JH, Liu YQ, Bao XY, Li FH. Li BM, et al. Arch Phys Med Rehabil. 2024 Mar;105(3):593-603. doi: 10.1016/j.apmr.2023.06.016. Epub 2023 Jul 5. Arch Phys Med Rehabil. 2024. PMID: 37419235 Review.

OBJECTIVE: To assess whether photobiomodulation therapy (PBMT) enhances the benefits of exercise in older adults. DATA SOURCES: PubMed, Scopus, Medline, and Web of Science, dated to February 2023. ...CONCLUSIONS: In older adults who exercise regularly, PBMT can pote …

OBJECTIVE: To assess whether photobiomodulation therapy (PBMT) enhances the benefits of exercise in older adults. DATA SOURCES …

28

Evaluation of the effect of different kinds of treatment modalities for temporomandibular joint pain and its relevance to chronic cervical pain: A randomized controlled trial.

Nemani SM, Chidambaranathan AS, Muthukumar B, Srinivasan S. Nemani SM, et al. J Indian Prosthodont Soc. 2024 Apr 1;24(2):128-135. doi: 10.4103/jips.jips_468_23. Epub 2024 Apr 23. J Indian Prosthodont Soc. 2024. PMID: 38650337 Free article. Clinical Trial.

AIM: The aim of this study was to evaluate the effect of different treatment modalities for temporomandibular joint (TMJ) pain and their relevance to chronic cervical pain after 12 months. SETTINGS AND DESIGN: This was a randomized controlled trial. ...Pearso …

AIM: The aim of this study was to evaluate the effect of different treatment modalities for temporomandibular joint (TMJ) pain …

29

Effectiveness of photobiomodulation and orofacial myofunctional therapy in orofacial pain disorders. A systematic review of randomized control trials.

Altuhafy M, Ahmed S, Jabr L, Khan J. Altuhafy M, et al. Lasers Med Sci. 2024 May 9;39(1):127. doi: 10.1007/s10103-024-04073-4. Lasers Med Sci. 2024. PMID: 38722392 Review.

Orofacial pain can significantly affect physical, psychological, and overall quality of life. This study aimed to compare the effectiveness of combining photobiomodulation (PBM) with orofacial myofunctional therapy (OMT) in managing orofacial pain diso …

Orofacial pain can significantly affect physical, psychological, and overall quality of life. This study aimed to compare the effecti …

30

Photobiomodulation of pain and inflammation in microcrystalline arthropathies: experimental and clinical results.

Soriano F, Campana V, Moya M, Gavotto A, Simes J, Soriano M, Soriano R, Spitale L, Palma J. Soriano F, et al. Photomed Laser Surg. 2006 Apr;24(2):140-50. doi: 10.1089/pho.2006.24.140. Photomed Laser Surg. 2006. PMID: 16706692 Clinical Trial.

BACKGROUND DATA: Microcrystalline arthropathies are prevalent among geriatric patients, who are more vulnerable to the side effects of drugs. The effectiveness of laser therapy for pain relief, free of side effects, has been reported in painful conditions. ...RESULT …

BACKGROUND DATA: Microcrystalline arthropathies are prevalent among geriatric patients, who are more vulnerable to the side effects of drugs …

31

Photobiomodulation inhibits inflammation in the temporomandibular joint of rats.

Mazuqueli Pereira ESB, Basting RT, Abdalla HB, Garcez AS, Napimoga MH, Clemente-Napimoga JT. Mazuqueli Pereira ESB, et al. J Photochem Photobiol B. 2021 Sep;222:112281. doi: 10.1016/j.jphotobiol.2021.112281. Epub 2021 Aug 5. J Photochem Photobiol B. 2021. PMID: 34388640

Photobiomodulation (PBM) has been applied as a non-invasive technique for treating temporomandibular joint symptoms, especially on painful condition's relief, however the anti-inflammatory mechanism underlying the effect of PBM remains uncertain. This study aims to …

Photobiomodulation (PBM) has been applied as a non-invasive technique for treating temporomandibular joint symptoms, especiall …

32

Molecular and Cellular Mechanisms of Arthritis in Children and Adults: New Perspectives on Applied Photobiomodulation.

Ailioaie LM, Litscher G. Ailioaie LM, et al. Int J Mol Sci. 2020 Sep 8;21(18):6565. doi: 10.3390/ijms21186565. Int J Mol Sci. 2020. PMID: 32911717 Free PMC article. Review.

Juvenile idiopathic arthritis and adult rheumatoid arthritis are two major groups with chronic joint pain and inflammation, extra-articular manifestations, and high risk of comorbidities, which can cause physical and ocular disability, as well as create great socio- …

Juvenile idiopathic arthritis and adult rheumatoid arthritis are two major groups with chronic joint pain and inflammation, ex …

33

Effect of photobiomodulation in the patellofemoral pain syndrome; randomized clinical trial in young women.

Pocai BL, Provensi É, Serighelli F, Rigo G, Artioli DP, de Albuquerque CE, Bertolini GRF. Pocai BL, et al. J Bodyw Mov Ther. 2021 Apr;26:263-267. doi: 10.1016/j.jbmt.2021.01.003. Epub 2021 Jan 12. J Bodyw Mov Ther. 2021. PMID: 33992256 Clinical Trial.

OBJECTIVE: patellofemoral pain syndrome (PFPS) is one of the most frequent musculoskeletal disorders in the knee joint, affecting mainly physically active adolescents and young adults; its main symptom is pain. Physiotherapy has several therapeutic modalities …

OBJECTIVE: patellofemoral pain syndrome (PFPS) is one of the most frequent musculoskeletal disorders in the knee joint, affect …

34

Evaluation of the effect of high-intensity laser therapy (HILT) on function, muscle strength, range of motion, pain level, and femoral cartilage thickness in knee osteoarthritis: randomized controlled study.

Ekici B, Ordahan B. Ekici B, et al. Lasers Med Sci. 2023 Sep 25;38(1):218. doi: 10.1007/s10103-023-03887-y. Lasers Med Sci. 2023. PMID: 37743421 Clinical Trial.

The aim of this study was to evaluate the effects of high-intensity laser therapy (HILT) on pain, range of motion, function, muscle strength, and femoral cartilage thickness in patients with knee osteoarthritis. ...The patients were evaluated with the determined sca …

The aim of this study was to evaluate the effects of high-intensity laser therapy (HILT) on pain, range of motion, function, m …

35

Photobiomodulation therapy on the palliative care of temporomandibular disorder and orofacial/cervical skull pain: study protocol for a randomized controlled clinical trial.

Carvalho FR, Barros RQ, Gonçalves AS, Freitas PM. Carvalho FR, et al. Trials. 2019 Apr 6;20(1):200. doi: 10.1186/s13063-019-3294-7. Trials. 2019. PMID: 30954086 Free PMC article.

BACKGROUND: Temporomandibular disorder (TMD) is the most common cause of orofacial and cervical skull pain and is considered to be a public health problem, affecting 5% to 12% of the world population. ...The main aim of these treatments is to relieve symptoms, reduce of …

BACKGROUND: Temporomandibular disorder (TMD) is the most common cause of orofacial and cervical skull pain and is considered to be a …

36

Intraoral photobiomodulation diminishes pain and improves functioning in women with temporomandibular disorder: a randomized, sham-controlled, double-blind clinical trial : Intraoral photobiomodulation diminishes pain in women with temporomandibular disorder.

Herpich CM, Leal-Junior ECP, Politti F, de Paula Gomes CAF, Dos Santos Glória IP, de Souza Amaral MFR, Herpich G, de Azevedo LMA, de Oliveira Gonzalez T, Biasotto-Gonzalez DA. Herpich CM, et al. Lasers Med Sci. 2020 Mar;35(2):439-445. doi: 10.1007/s10103-019-02841-1. Epub 2019 Jul 19. Lasers Med Sci. 2020. PMID: 31325122 Clinical Trial.

The aim of the present study was to evaluate the effect of intraoral photobiomodulation involving super-pulsed laser (905 nm) combined with red (640 nm) and infrared (875 nm) light-emitting diodes on pain, mandibular range of motion, and functioning in women …

The aim of the present study was to evaluate the effect of intraoral photobiomodulation involving super-pulsed laser (905 nm) combine …

37

Comparison of photobiomodulation therapy and suprascapular nerve-pulsed radiofrequency in chronic shoulder pain: a randomized controlled, single-blind, clinical trial.

Ökmen BM, Ökmen K. Ökmen BM, et al. Lasers Med Sci. 2017 Nov;32(8):1719-1726. doi: 10.1007/s10103-017-2237-3. Epub 2017 May 25. Lasers Med Sci. 2017. PMID: 28547075 Clinical Trial.

We aimed to examine the efficacy of photobiomodulation therapy (PBMT) and suprascapular nerve (SSN)-pulsed radiofrequency (RF) therapy. ...We established that PBMT and SSN-pulsed RF therapy are effective methods, in addition to exercise therapy, …

We aimed to examine the efficacy of photobiomodulation therapy (PBMT) and suprascapular nerve (SSN)-pulsed radiofrequency (RF) …

38

Photobiomodulation (lambda=808nm) and Platelet-Rich Plasma (PRP) for the Treatment of Acute Rheumatoid Arthritis in Wistar Rats.

Gonçalves AB, Bovo JL, Gomes BS, Pigoso AA, Felonato M, Esquisatto MAM, Filho GJL, do Bomfim FRC. Gonçalves AB, et al. J Lasers Med Sci. 2021 Oct 18;12:e60. doi: 10.34172/jlms.2021.60. eCollection 2021. J Lasers Med Sci. 2021. PMID: 35155145 Free PMC article.

Introduction: Rheumatoid arthritis (RA) causes inflammation, pain, edema, and articular degradation and its treatment can be based on anti-inflammatory drugs, photobiomodulation (PBM) and/or platelet-rich plasma (PRP) that can decrease cell flow and promote local he …

Introduction: Rheumatoid arthritis (RA) causes inflammation, pain, edema, and articular degradation and its treatment can be based on …

39

Photobiomodulation in Temporomandibular Disorders.

Tunér J, Hosseinpour S, Fekrazad R. Tunér J, et al. Photobiomodul Photomed Laser Surg. 2019 Dec;37(12):826-836. doi: 10.1089/photob.2019.4705. Epub 2019 Nov 26. Photobiomodul Photomed Laser Surg. 2019. PMID: 31770071

Objective: This systematic review aimed to comprehensively review all available documents regarding photobiomodulation therapy (PBMT) application in temporomandibular disorder (TMD) patients and to suggest an evidence-based protocol for therapeutic PBM administratio …

Objective: This systematic review aimed to comprehensively review all available documents regarding photobiomodulation therapy …

40

The effectiveness of photobiomodulation in the management of temporomandibular pain sensitivity in rats: behavioral and neurochemical effects.

de Freitas Rodrigues A, de Oliveira Martins D, Chacur M, Luz JGC. de Freitas Rodrigues A, et al. Lasers Med Sci. 2020 Mar;35(2):447-453. doi: 10.1007/s10103-019-02842-0. Epub 2019 Jul 10. Lasers Med Sci. 2020. PMID: 31292820

This study analyzed the effects of photobiomodulation (PBM) with low-level laser therapy on nociceptive behavior and neuronal activity in the trigeminal nucleus after experimental unilateral temporomandibular joint (TMJ) disc injury. ...There wa …

This study analyzed the effects of photobiomodulation (PBM) with low-level laser therapy on nociceptive behavior …

41

Meta-analysis of pain relief effects by laser irradiation on joint areas.

Jang H, Lee H. Jang H, et al. Photomed Laser Surg. 2012 Aug;30(8):405-17. doi: 10.1089/pho.2012.3240. Epub 2012 Jun 29. Photomed Laser Surg. 2012. PMID: 22747309 Free PMC article. Review.

However, its true effectiveness is still controversial because several clinical trials have reported the ineffectiveness of lasers in treating pain. METHODS: In this systematic review, we investigate the clinical effectiveness of low-level laser therapy …

However, its true effectiveness is still controversial because several clinical trials have reported the ineffectiveness of lasers in treati …

42

Effectiveness of low-level laser therapy combined with an exercise program to reduce pain and increase function in adults with shoulder pain: a critically appraised topic.

Thornton AL, McCarty CW, Burgess MJ. Thornton AL, et al. J Sport Rehabil. 2013 Feb;22(1):72-8. doi: 10.1123/jsr.22.1.72. Epub 2012 Oct 11. J Sport Rehabil. 2013. PMID: 23069702 Review.

Recently, low-level laser therapy (LLLT) has been used as an additional modality in the conservative management of patients with shoulder pain. However, the true effectiveness of LLLT in decreasing pain and increasing function in patients with s …

Recently, low-level laser therapy (LLLT) has been used as an additional modality in the conservative management of pati …

43

Photobiomodulation via a cluster device associated with a physical exercise program in the level of pain and muscle strength in middle-aged and older women with knee osteoarthritis: a randomized placebo-controlled trial.

Vassão PG, de Souza MC, Silva BA, Junqueira RG, de Camargo MR, Dourado VZ, Tucci HT, Renno AC. Vassão PG, et al. Lasers Med Sci. 2020 Feb;35(1):139-148. doi: 10.1007/s10103-019-02807-3. Epub 2019 May 29. Lasers Med Sci. 2020. PMID: 31144070 Clinical Trial.

Osteoarthritis (OA) is a chronic joint disease that leads to pain and functional incapacity. The aim of the study is to investigate the effects of the incorporation of photobiomodulation (PBM) (via cluster) into a physical exercise program on the level of …

Osteoarthritis (OA) is a chronic joint disease that leads to pain and functional incapacity. The aim of the study is to invest …

44

Geriatric Freshwater and Marine Fish.

Boylan S. Boylan S. Vet Clin North Am Exot Anim Pract. 2020 Sep;23(3):471-484. doi: 10.1016/j.cvex.2020.05.001. Vet Clin North Am Exot Anim Pract. 2020. PMID: 32778229 Review.

As pain management finally becomes accepted for this last of the vertebrate taxa, fish medicine is finally reaching the sophistication of other vertebrates. ...The degenerative organ/tissue changes and neoplasias of fish deserve the same diagnosis and treatments of their t …

As pain management finally becomes accepted for this last of the vertebrate taxa, fish medicine is finally reaching the sophisticatio …

45

Simultaneous red and infrared light-emitting diodes reduced pain in individuals with temporomandibular disorder: a randomized, controlled, double-blind, clinical trial.

de Sousa DFM, Malavazzi TCDS, Deana AM, Horliana ACRT, Fernandes KPS, Bussadori SK, Mesquita-Ferrari RA. de Sousa DFM, et al. Lasers Med Sci. 2022 Dec;37(9):3423-3431. doi: 10.1007/s10103-022-03600-5. Epub 2022 Jun 24. Lasers Med Sci. 2022. PMID: 35751005 Clinical Trial.

The aim of the present study was to evaluate the effects of photobiomodulation (PBM) with the simultaneous use of red and infrared LEDs on pain and mandibular range of motion in individuals with temporomandibular disorder (TMD). ...The device was placed in the regio …

The aim of the present study was to evaluate the effects of photobiomodulation (PBM) with the simultaneous use of red and infrared LE …

46

Effects of photobiomodulation associated with orofacial myofactional therapy on temporomandibular joint dysfunction.

Alves GÂDS, Gondim YRDR, Lima JAS, Silva MAPD, Florêncio DSF, Almeida LNA, Silva HJD. Alves GÂDS, et al. Codas. 2021 Jun 4;33(6):e20200193. doi: 10.1590/2317-1782/20202020193. eCollection 2021. Codas. 2021. PMID: 34105614 Free article. Clinical Trial. English, Portuguese.

PURPOSE: To investigate the influence of photobiomodulation associated with orofacial myofunctional therapy (OMT) in patients with temporomandibular muscle disorders (TMD). ...The experimental group (EG) consisted of five women submitted to orofacial myofunctional …

PURPOSE: To investigate the influence of photobiomodulation associated with orofacial myofunctional therapy (OMT) in patients …

47

What are the best parameters of low-level laser therapy to reduce pain intensity and improve mandibular function in orofacial pain? A systematic review and meta-analysis.

de Oliveira-Souza AIS, Mohamad N, de Castro Carletti EM, Müggenborg F, Dennett L, de Oliveira DA, Armijo-Olivo S. de Oliveira-Souza AIS, et al. Disabil Rehabil. 2023 Oct;45(20):3219-3237. doi: 10.1080/09638288.2022.2127933. Epub 2022 Oct 20. Disabil Rehabil. 2023. PMID: 36263978

PURPOSE: To determine the effectiveness of laser therapy for managing patients with orofacial pain (OFP). In addition, to determine which parameters provide the best treatment effects to reduce pain, improve function, and quality of life in adults with OFP. . …

PURPOSE: To determine the effectiveness of laser therapy for managing patients with orofacial pain (OFP). In addition, to dete …

48

Effects of exercise training and photobiomodulation therapy (EXTRAPHOTO) on pain in women with fibromyalgia and temporomandibular disorder: study protocol for a randomized controlled trial.

da Silva MM, Albertini R, Leal-Junior EC, de Tarso Camillo de Carvalho P, Silva JA Jr, Bussadori SK, de Oliveira LV, Casarin CA, Andrade EL, Bocalini DS, Serra AJ. da Silva MM, et al. Trials. 2015 Jun 4;16:252. doi: 10.1186/s13063-015-0765-3. Trials. 2015. PMID: 26040789 Free PMC article. Clinical Trial.

The literature is unclear regarding an effective therapy for reducing pain in patients with both comorbidities. Exercise training and phototherapy (low-level laser therapy with light-emitting diode) are two of the approaches used to treat …

The literature is unclear regarding an effective therapy for reducing pain in patients with both comorbidities. Exercise train …

49

Low-Level Laser and Light Therapy After Total Knee Arthroplasty Improves Postoperative Pain and Functional Outcomes: A Three-Arm Randomized Clinical Trial.

Bahrami H, Moharrami A, Mirghaderi P, Mortazavi SMJ. Bahrami H, et al. Arthroplast Today. 2022 Dec 5;19:101066. doi: 10.1016/j.artd.2022.10.016. eCollection 2023 Feb. Arthroplast Today. 2022. PMID: 36507283 Free PMC article.

BACKGROUND: We examined the effect of low-level laser therapy (LLLT) and Bioptron light therapy on pain and function following primary total knee arthroplasty. ...CONCLUSIONS: In the early stages of recovery after total knee arthroplasty, …

BACKGROUND: We examined the effect of low-level laser therapy (LLLT) and Bioptron light therapy on pai …

50

Photobiomodulation Therapy for the Symptoms Related to Temporomandibular Joint Disk Displacement.

Regulski PA, Szopinski KT, Levičnik-Höfferle Š. Regulski PA, et al. Case Rep Dent. 2023 Apr 13;2023:5947168. doi: 10.1155/2023/5947168. eCollection 2023. Case Rep Dent. 2023. PMID: 37089525 Free PMC article.

Pain related to temporomandibular disorders (TMD) is a common problem that can significantly influence a patient's quality of life. Laser photobiomodulation (PBM) has been reported as a promising method in medicine for wound and bone healing, pain relief, and …

Pain related to temporomandibular disorders (TMD) is a common problem that can significantly influence a patient's quality of life. L …

51

Rehabilitation of companion animals following orthopaedic surgery.

Baltzer WI. Baltzer WI. N Z Vet J. 2020 May;68(3):157-167. doi: 10.1080/00480169.2020.1722271. Epub 2020 Feb 23. N Z Vet J. 2020. PMID: 31996106 Review.

During the first 72 hours, rehabilitation should focus on reduction of inflammation and pain, maintaining joint nutrition and range of motion, and stimulating vascularisation and healing; and may include cryotherapy, passive range of motion exercises, massage and th …

During the first 72 hours, rehabilitation should focus on reduction of inflammation and pain, maintaining joint nutrition and …

52

Investigation of the effects of therapeutic ultrasound or photobiomodulation and the role of spinal glial cells in osteoarthritis-induced nociception in mice.

Malta I, Moraes T, Elisei L, Novaes R, Galdino G. Malta I, et al. Lasers Med Sci. 2022 Apr;37(3):1687-1698. doi: 10.1007/s10103-021-03418-7. Epub 2021 Sep 20. Lasers Med Sci. 2022. PMID: 34542770

Additionally, the mice received chronic ultrasound or photobiomodulation treatment for 21 days or a single treatment at day 14. Nociception was evaluated using von Frey filaments, and osteoarthritis symptoms were assessed by analysis of gait, joint temperature, and …

Additionally, the mice received chronic ultrasound or photobiomodulation treatment for 21 days or a single treatment at day 14. Nocic …

53

Effectiveness of Photobiomodulation in Temporomandibular Disorder-Related Pain Using a 635 nm Diode Laser: A Randomized, Blinded, and Placebo-Controlled Clinical Trial.

Monteiro L, Ferreira R, Resende T, Pacheco JJ, Salazar F. Monteiro L, et al. Photobiomodul Photomed Laser Surg. 2020 May;38(5):280-288. doi: 10.1089/photob.2019.4730. Photobiomodul Photomed Laser Surg. 2020. PMID: 32427553 Clinical Trial.

Objective: We aimed to evaluate the efficacy of photobiomodulation (PBM), using an 635 nm diode laser, to provide pain relief for temporomandibular disorder (TMD). ...Reduction of pain during palpation of most masticatory muscles was significant following tre …

Objective: We aimed to evaluate the efficacy of photobiomodulation (PBM), using an 635 nm diode laser, to provide pain relief …

54

Effects of low-level laser therapy on joint pain, synovitis, anabolic, and catabolic factors in a progressive osteoarthritis rabbit model.

Wang P, Liu C, Yang X, Zhou Y, Wei X, Ji Q, Yang L, He C. Wang P, et al. Lasers Med Sci. 2014 Nov;29(6):1875-85. doi: 10.1007/s10103-014-1600-x. Epub 2014 Jun 3. Lasers Med Sci. 2014. PMID: 24890034

The aim of this study was to investigate the effect of low-level laser therapy (LLLT) on short-term and long-term joint pain, synovitis, anabolic, and catabolic factors in the cartilage of a rabbit model with progressive osteoarthritis (OA) indu …

The aim of this study was to investigate the effect of low-level laser therapy (LLLT) on short-term and long-term jo …

55

Feasibility and therapeutic efficacy of a two-week low-level laser acupuncture therapy for shoulder and neck pain in office workers: Protocol for a pilot, single-blind, double-armed, randomised controlled trial.

Wang CC, Whitehead L, Cruickshank T, Lo J, Xia JC, Wen J. Wang CC, et al. PLoS One. 2022 Jan 21;17(1):e0260846. doi: 10.1371/journal.pone.0260846. eCollection 2022. PLoS One. 2022. PMID: 35061682 Free PMC article. Clinical Trial.

The non-invasive, painless, non-infectious, and safe modality of low-level laser acupuncture (LLLA) has shown promise for SNP management. OBJECTIVE: The overarching aim of this study is to provide evidence of the feasibility and therapeutic efficacy of LLLA for offi …

The non-invasive, painless, non-infectious, and safe modality of low-level laser acupuncture (LLLA) has shown promise for SNP …

56

Influence of various laser therapy methods on knee joint pain and function in patients with knee osteoarthritis.

Gworys K, Gasztych J, Puzder A, Gworys P, Kujawa J. Gworys K, et al. Ortop Traumatol Rehabil. 2012 May-Jun;14(3):269-77. doi: 10.5604/15093492.1002257. Ortop Traumatol Rehabil. 2012. PMID: 22764339 Clinical Trial. English, Polish.

BACKGROUND: The aim of the study was to estimate the influence of various laser therapy methods on knee joint pain and function in patients with knee osteoarthritis. MATERIAL AND METHODS: 125 patients were randomly assigned to 4 groups: group I received one-w …

BACKGROUND: The aim of the study was to estimate the influence of various laser therapy methods on knee joint pain and …

57

Rapid LLLT protocol for myofascial pain and mouth opening limitation treatment in the clinical practice: An RCT.

De Oliveira Chami V, Maracci LM, Tomazoni F, Centeno ACT, Porporatti AL, Ferrazzo VA, Marquezan M. De Oliveira Chami V, et al. Cranio. 2022 Jul;40(4):334-340. doi: 10.1080/08869634.2020.1773660. Epub 2020 Jun 3. Cranio. 2022. PMID: 32491956

OBJECTIVE: To evaluate the effect of a rapid treatment protocol of low-level laser therapy (LLLT) in patients with myofascial pain and mouth opening limitation. ...A significant increase in the maximum mouth opening (p = 0.04) and improvement in OHIP/T …

OBJECTIVE: To evaluate the effect of a rapid treatment protocol of low-level laser therapy (LLLT) in patients with myof …

58

Low-Level Laser Therapy for Rheumatoid Arthritis: A Review of Experimental Approaches.

Hossein-Khannazer N, Kazem Arki M, Keramatinia A, Rezaei-Tavirani M. Hossein-Khannazer N, et al. J Lasers Med Sci. 2022 Dec 10;13:e62. doi: 10.34172/jlms.2022.62. eCollection 2022. J Lasers Med Sci. 2022. PMID: 37041796 Free PMC article. Review.

Introduction: Rheumatoid arthritis (RA) is an inflammatory and autoimmune disorder that is characterized by joint inflammation, pain, physical disability, and morning stiffness. In the present study, the effect of low-level laser therapy (LLLT) …

Introduction: Rheumatoid arthritis (RA) is an inflammatory and autoimmune disorder that is characterized by joint inflammation, pa …

59

Effectiveness of low-level laser therapy on pain intensity, pressure pain threshold, and SF-MPQ indexes of women with myofascial pain.

Magri LV, Carvalho VA, Rodrigues FC, Bataglion C, Leite-Panissi CR. Magri LV, et al. Lasers Med Sci. 2017 Feb;32(2):419-428. doi: 10.1007/s10103-016-2138-x. Epub 2017 Jan 4. Lasers Med Sci. 2017. PMID: 28054261 Clinical Trial.

The low-level laser therapy (LLLT) has been reported as a therapeutic option for the painful TMD treatment. The aim of this study was to analyze the effect of LLLT on pain intensity (visual analogue scale, VAS), pain sensitivity in orofacial and …

The low-level laser therapy (LLLT) has been reported as a therapeutic option for the painful TMD treatment. The aim of …

60

Advances in photobiomodulation for cognitive improvement by near-infrared derived multiple strategies.

Pan WT, Liu PM, Ma D, Yang JJ. Pan WT, et al. J Transl Med. 2023 Feb 22;21(1):135. doi: 10.1186/s12967-023-03988-w. J Transl Med. 2023. PMID: 36814278 Free PMC article. Review.

Cognitive function is an important ability of the brain, but cognitive dysfunction can easily develop once the brain is injured in various neuropathological conditions or diseases. Photobiomodulation therapy is a type of noninvasive physical therapy that is g …

Cognitive function is an important ability of the brain, but cognitive dysfunction can easily develop once the brain is injured in various n …

61

Comparative effectiveness of photobiomodulation and manual therapy alone or combined in TMD patients: a randomized clinical trial.

Brochado FT, Jesus LH, Carrard VC, Freddo AL, Chaves KD, Martins MD. Brochado FT, et al. Braz Oral Res. 2018 Jul 10;32:e50. doi: 10.1590/1807-3107bor-2018.vol32.0050. Braz Oral Res. 2018. PMID: 29995062 Free article. Clinical Trial.

The effectiveness of photobiomodulation (PBM) and manual therapy (MT), alone or combined (CT), were evaluated in pain intensity, mandibular movements, psychosocial aspects, and anxiety symptoms of temporomandibular disorder (TMD) patients. ...All groups demon …

The effectiveness of photobiomodulation (PBM) and manual therapy (MT), alone or combined (CT), were evaluated in pain i …

62

Comparative effectiveness of low-level laser therapy with different wavelengths and transcutaneous electric nerve stimulation in the treatment of pain caused by temporomandibular disorders: A systematic review and network meta-analysis.

Ren H, Liu J, Liu Y, Yu C, Bao G, Kang H. Ren H, et al. J Oral Rehabil. 2022 Feb;49(2):138-149. doi: 10.1111/joor.13230. Epub 2021 Aug 21. J Oral Rehabil. 2022. PMID: 34289157 Review.

OBJECTIVE: To assess the efficacy of low-level laser therapy (LLLT) with different wavelengths and transcutaneous electric nerve stimulation (TENS) and explore the optimal wavelength range of laser application in the treatment of pain caused by temporo …

OBJECTIVE: To assess the efficacy of low-level laser therapy (LLLT) with different wavelengths and transcutaneous elect …

63

Photobiomodulation with simultaneous use of red and infrared light emitting diodes in the treatment of temporomandibular disorder: study protocol for a randomized, controlled and double-blind clinical trial.

Sousa DFM, Gonçalves MLL, Politti F, Lovisetto RDP, Fernandes KPS, Bussadori SK, Mesquita-Ferrari RA. Sousa DFM, et al. Medicine (Baltimore). 2019 Feb;98(6):e14391. doi: 10.1097/MD.0000000000014391. Medicine (Baltimore). 2019. PMID: 30732181 Free PMC article.

Due to its complexity there are already treatments using various forms of therapy. Photobiomodulation using light sources, such as low-level laser or light emitting diodes (LED), with different wavelengths, in a single or combined form, a …

Due to its complexity there are already treatments using various forms of therapy. Photobiomodulation using light sourc …

64

Evaluation of pain, jaw movements, and psychosocial factors in elderly individuals with temporomandibular disorder under laser phototherapy.

Rodrigues JH, Marques MM, Biasotto-Gonzalez DA, Moreira MS, Bussadori SK, Mesquita-Ferrari RA, Martins MD. Rodrigues JH, et al. Lasers Med Sci. 2015 Apr;30(3):953-9. doi: 10.1007/s10103-013-1514-z. Epub 2013 Dec 24. Lasers Med Sci. 2015. PMID: 24366293 Clinical Trial.

Two settings of irradiations were applied as follows: in patients presenting myofascial pain, 10 mW, 5 J/cm(2), 20 s, 0.2 J per application point; and in patients with joint TMD, 70 mW, 105 J/cm(2), 60 s on five points, 4.2 J per point. ...Data was statistically ana …

Two settings of irradiations were applied as follows: in patients presenting myofascial pain, 10 mW, 5 J/cm(2), 20 s, 0.2 J per appli …

65

Efficacy of Low-Level Laser Therapy in the Treatment of Temporomandibular Myofascial Pain: A Systematic Review and Meta-Analysis.

Munguia FM, Jang J, Salem M, Clark GT, Enciso R. Munguia FM, et al. J Oral Facial Pain Headache. 2018 Summer;32(3):287–297. doi: 10.11607/ofph.2032. Epub 2018 Apr 25. J Oral Facial Pain Headache. 2018. PMID: 29697718 Review.

AIMS: To conduct a systematic review and meta-analysis to determine the efficacy of low-level laser therapy (LLLT) in treating temporomandibular myofascial pain in adults compared to laser placebo. ...CONCLUSION: The findings from this systematic revie …

AIMS: To conduct a systematic review and meta-analysis to determine the efficacy of low-level laser therapy (LLLT) in t …

66

Comparative Study of the Physiotherapeutic and Drug Protocol and Low-Level Laser Irradiation in the Treatment of Pain Associated with Temporomandibular Dysfunction.

Cavalcanti MF, Silva UH, Leal-Junior EC, Lopes-Martins RA, Marcos RL, Pallotta RC, Diomede F, Trubiani O, De Isla N, Frigo L. Cavalcanti MF, et al. Photomed Laser Surg. 2016 Dec;34(12):652-656. doi: 10.1089/pho.2016.4195. Epub 2016 Nov 29. Photomed Laser Surg. 2016. PMID: 27898256

Orthopedic and musculoskeletal changes can also cause temporomandibular disorders (TMD) and pain. Low-level laser (LLL) therapy has been studied in the treatment of temporomandibular jaw (TMJ) dysfunction, and controversial results were obtained. ...Se …

Orthopedic and musculoskeletal changes can also cause temporomandibular disorders (TMD) and pain. Low-level laser (LLL) …

67

Wavelength effect in temporomandibular joint pain: a clinical experience.

Carvalho CM, de Lacerda JA, dos Santos Neto FP, Cangussu MC, Marques AM, Pinheiro AL. Carvalho CM, et al. Lasers Med Sci. 2010 Mar;25(2):229-32. doi: 10.1007/s10103-009-0695-y. Epub 2009 Jun 30. Lasers Med Sci. 2010. PMID: 19565312

Temporomandibular disorders (TMDs) are common painful multifactorial conditions affecting the temporomandibular joint (TMJ) and whose treatment depends on the type and symptoms. Initially, it requires pain control, and, for this, drugs, biting plates, occlusal adjus …

Temporomandibular disorders (TMDs) are common painful multifactorial conditions affecting the temporomandibular joint (TMJ) and whose …

68

Low-level laser therapy for treatment of temporomandibular joint pain: a double-blind and placebo-controlled trial.

Emshoff R, Bösch R, Pümpel E, Schöning H, Strobl H. Emshoff R, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Apr;105(4):452-6. doi: 10.1016/j.tripleo.2007.09.012. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008. PMID: 18329580 Clinical Trial.

OBJECTIVE: The objective of this study was to assess the effectiveness of low-level laser therapy (LLLT) in the management of temporomandibular joint (TMJ) pain in a random and double-blind research design. ...Measures of TMJ pain during …

OBJECTIVE: The objective of this study was to assess the effectiveness of low-level laser therapy (LLLT) in the managem …

69

Role of Photobiomodulation Therapy in Modulating Oxidative Stress in Temporomandibular Disorders. A Systematic Review and Meta-Analysis of Human Randomised Controlled Trials.

Hanna R, Dalvi S, Bensadoun RJ, Benedicenti S. Hanna R, et al. Antioxidants (Basel). 2021 Jun 25;10(7):1028. doi: 10.3390/antiox10071028. Antioxidants (Basel). 2021. PMID: 34202292 Free PMC article. Review.

This systematic review and meta-analysis (PROSPERO registration; ref CRD 42020198921) aimed to govern photobiomodulation therapy (PBMT) efficacy in temporomandibular disorder (TMD). PRISMA guidelines and Cochrane Collaboration recommendations were followed. Differen …

This systematic review and meta-analysis (PROSPERO registration; ref CRD 42020198921) aimed to govern photobiomodulation therapy …

70

Laser Acupuncture Treatment Improves Pain and Functional Status in Patients with Subacromial Impingement Syndrome: A Randomized, Double-Blind, Sham-Controlled Study.

Kibar S, Konak HE, Evcik D, Ay S. Kibar S, et al. Pain Med. 2017 May 1;18(5):980-987. doi: 10.1093/pm/pnw197. Pain Med. 2017. PMID: 27816913 Clinical Trial.

The patients were assessed at baseline and after 15 sessions of laser treatment. Pain severity and doctor's and patient's global assessments were measured via visual analog scale (VAS). ...All parameters of pain and functional status in the treatment group were sign …

The patients were assessed at baseline and after 15 sessions of laser treatment. Pain severity and doctor's and patient's global asse …

71

Evaluation of low-level laser therapy effectiveness on the pain and masticatory performance of patients with myofascial pain.

de Moraes Maia ML, Ribeiro MA, Maia LG, Stuginski-Barbosa J, Costa YM, Porporatti AL, Conti PC, Bonjardim LR. de Moraes Maia ML, et al. Lasers Med Sci. 2014 Jan;29(1):29-35. doi: 10.1007/s10103-012-1228-7. Epub 2012 Nov 10. Lasers Med Sci. 2014. PMID: 23143142 Clinical Trial.

This study investigated the effect of low-level laser therapy (LLLT) on the masticatory performance (MP), pressure pain threshold (PPT), and pain intensity in patients with myofascial pain. ...The measured variables were: (1) MP by analys …

This study investigated the effect of low-level laser therapy (LLLT) on the masticatory performance (MP), pressure p …

72

Effects of low-level laser therapy in adults with rheumatoid arthritis: A systematic review and meta-analysis of controlled trials.

Lourinho I, Sousa T, Jardim R, Pinto AC, Iosimuta N. Lourinho I, et al. PLoS One. 2023 Sep 8;18(9):e0291345. doi: 10.1371/journal.pone.0291345. eCollection 2023. PLoS One. 2023. PMID: 37683021 Free PMC article.

Several physical therapy resources are used in the treatment of AR, such as low-level laser therapy (LLLT) and its analgesic and anti-inflammatory effects. ...The objective of this study is to evaluate the efficacy of low-level laser t …

Several physical therapy resources are used in the treatment of AR, such as low-level laser therapy (LLLT) and i …

73

Thermographic and clinical evaluation of 808-nm laser photobiomodulation effects after third molar extraction.

Pedreira AA, Wanderley FG, Sa MF, Viena CS, Perez A, Hoshi R, Leite MP, Reis SR, Medrado AP. Pedreira AA, et al. Minerva Stomatol. 2016 Aug;65(4):213-22. Minerva Stomatol. 2016. PMID: 27374361 Clinical Trial.

Group I and Group III received mock laser therapy in which the device was powered off, and Group II and Group IV were exposed to laser light. ...Laser therapy had a significant influence on the local circulation in the area near the temporomandibular joint …

Group I and Group III received mock laser therapy in which the device was powered off, and Group II and Group IV were exposed to lase …

74

Randomized, blinded, controlled trial on effectiveness of photobiomodulation therapy and exercise training in the fibromyalgia treatment.

da Silva MM, Albertini R, de Tarso Camillo de Carvalho P, Leal-Junior ECP, Bussadori SK, Vieira SS, Bocalini DS, de Oliveira LVF, Grandinetti V, Silva JA Jr, Serra AJ. da Silva MM, et al. Lasers Med Sci. 2018 Feb;33(2):343-351. doi: 10.1007/s10103-017-2388-2. Epub 2017 Nov 23. Lasers Med Sci. 2018. PMID: 29170901 Clinical Trial.

Quality of life was assessed through SF-36 survey. Set 1: pain threshold was improved with the phototherapy, and EXT improved the pain threshold for temporomandibular joint (right and left body side) and occipital site (right body side). ...Moreover, quality …

Quality of life was assessed through SF-36 survey. Set 1: pain threshold was improved with the phototherapy, and EXT improved the …

75

The effect of low-level laser therapy and physical exercise on pain, stiffness, function, and spatiotemporal gait variables in subjects with bilateral knee osteoarthritis: a blind randomized clinical trial.

de Matos Brunelli Braghin R, Libardi EC, Junqueira C, Rodrigues NC, Nogueira-Barbosa MH, Renno ACM, Carvalho de Abreu DC. de Matos Brunelli Braghin R, et al. Disabil Rehabil. 2019 Dec;41(26):3165-3172. doi: 10.1080/09638288.2018.1493160. Epub 2018 Oct 16. Disabil Rehabil. 2019. PMID: 30324827 Clinical Trial.

Objective: To evaluate the effects of individual and combination therapies (low-level laser therapy and physical exercises) on pain, stiffness, function, and spatiotemporal gait variables in subjects with bilateral knee osteoarthritis (OA).Methods: Sub …

Objective: To evaluate the effects of individual and combination therapies (low-level laser therapy and physical exerci …

76

Effectiveness of physiotherapy and GaAlAs laser in the management of temporomandibular joint disorders.

Dostalová T, Hlinakova P, Kasparova M, Rehacek A, Vavrickova L, Navrátil L. Dostalová T, et al. Photomed Laser Surg. 2012 May;30(5):275-80. doi: 10.1089/pho.2011.3171. Photomed Laser Surg. 2012. PMID: 22551049 Free PMC article.

OBJECTIVE: Low-level laser therapy (LLLT) is a treatment method commonly used in physiotherapy for musculoskeletal disorders. ...RESULTS: Baseline comparisons between the healthy patients and patients with low-level laser application show that T …

OBJECTIVE: Low-level laser therapy (LLLT) is a treatment method commonly used in physiotherapy for musculoskeletal diso …

77

Effectiveness of occlusal splints and low-level laser therapy on myofascial pain.

Demirkol N, Sari F, Bulbul M, Demirkol M, Simsek I, Usumez A. Demirkol N, et al. Lasers Med Sci. 2015 Apr;30(3):1007-12. doi: 10.1007/s10103-014-1522-7. Epub 2014 Feb 7. Lasers Med Sci. 2015. PMID: 24504660 Clinical Trial.

The present study was designed to evaluate the effects of low-level laser (Nd:YAG) therapy and occlusal splints in patients with signs and symptoms of temporomandibular disorders (TMD) characterized with myofascial pain (MP). ...The first group was occ …

The present study was designed to evaluate the effects of low-level laser (Nd:YAG) therapy and occlusal splints in pati …

78

A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders.

Bjordal JM, Couppé C, Chow RT, Tunér J, Ljunggren EA. Bjordal JM, et al. Aust J Physiother. 2003;49(2):107-16. doi: 10.1016/s0004-9514(14)60127-6. Aust J Physiother. 2003. PMID: 12775206 Review.

We investigated if low level laser therapy (LLLT) of the joint capsule can reduce pain in chronic joint disorders. ...Low level laser therapy with the suggested dose range significantly reduces pain and improve …

We investigated if low level laser therapy (LLLT) of the joint capsule can reduce pain in chronic join …

79

A systematic review of conservative interventions for osteoarthritis of the hand.

Valdes K, Marik T. Valdes K, et al. J Hand Ther. 2010 Oct-Dec;23(4):334-50; quiz 351. doi: 10.1016/j.jht.2010.05.001. Epub 2010 Jul 8. J Hand Ther. 2010. PMID: 20615662 Review.

STUDY DESIGN: Systematic Review. INTRODUCTION: Hand therapy interventions for patients with hand osteoarthritis (OA) can include splinting, joint protection technique instruction, paraffin, exercises, and provision of a home exercise program. ...RESULTS: The current …

STUDY DESIGN: Systematic Review. INTRODUCTION: Hand therapy interventions for patients with hand osteoarthritis (OA) can include spli …

80

Low-level laser therapy and myofacial pain dysfunction syndrome: a randomized controlled clinical trial.

Shirani AM, Gutknecht N, Taghizadeh M, Mir M. Shirani AM, et al. Lasers Med Sci. 2009 Sep;24(5):715-20. doi: 10.1007/s10103-008-0624-5. Epub 2008 Nov 12. Lasers Med Sci. 2009. PMID: 19002646 Clinical Trial.

The effects of low-level lasers (LLLs) for controlling the discomfort of patients are investigated frequently. ...In each group the reduction of pain before and after the treatment was meaningful, but, between the two groups, low-level laser …

The effects of low-level lasers (LLLs) for controlling the discomfort of patients are investigated frequently. ...In each grou …

81

Effect of photobiomodulation therapy on painful temporomandibular disorders.

Aisaiti A, Zhou Y, Wen Y, Zhou W, Wang C, Zhao J, Yu L, Zhang J, Wang K, Svensson P. Aisaiti A, et al. Sci Rep. 2021 Apr 27;11(1):9049. doi: 10.1038/s41598-021-87265-0. Sci Rep. 2021. PMID: 33907210 Free PMC article. Clinical Trial.

To evaluate the effect of photobiomodulation therapy (PBMT) on painful temporomandibular disorders (TMD) patients in a randomized, double-blinded, placebo-controlled manner. ...Data were analyzed with a mixed model analysis of variance (ANOVA). Pain intensity …

To evaluate the effect of photobiomodulation therapy (PBMT) on painful temporomandibular disorders (TMD) patients in a randomi …

82

Light-emitting diode photobiomodulation therapy for non-specific low back pain in working nurses: A single-center, double-blind, prospective, randomized controlled trial.

Lin YP, Su YH, Chin SF, Chou YC, Chia WT. Lin YP, et al. Medicine (Baltimore). 2020 Aug 7;99(32):e21611. doi: 10.1097/MD.0000000000021611. Medicine (Baltimore). 2020. PMID: 32769919 Free PMC article. Clinical Trial.

A number of European countries are experiencing a shortage of healthcare workers. Light therapy has been shown to be an effective treatment for various musculoskeletal disorders, including lateral epicondylitis, temporomandibular joint pain, carpal tun …

A number of European countries are experiencing a shortage of healthcare workers. Light therapy has been shown to be an effect …

83

Comparison of low level laser therapy and interferential current on post stroke shoulder pain.

Jan F, Naeem A, Malik AN, Amjad I, Malik T. Jan F, et al. J Pak Med Assoc. 2017 May;67(5):788-789. J Pak Med Assoc. 2017. PMID: 28507373 Clinical Trial.

The variables under study were pain, satisfaction, disability, and function level before and after treatment. Improvement in pain and satisfaction level after LASER therapy was significant (p<0.001). ...The study findings revealed that LASER therapy …

The variables under study were pain, satisfaction, disability, and function level before and after treatment. Improvement in pain …

84

Does low intensity laser therapy reduce pain and change orofacial myofunctional conditions?

Melchior Mde O, Venezian GC, Machado BC, Borges RF, Mazzetto MO. Melchior Mde O, et al. Cranio. 2013 Apr;31(2):133-9. doi: 10.1179/crn.2013.021. Cranio. 2013. PMID: 23795403

Due to its multifactorial pain aspects, combined therapies are required for the the comprehensive management of temporomandibular joint disorders (TMD). ...The aims of this study were the following: 1. verify whether low-intensity laser therapy would promote …

Due to its multifactorial pain aspects, combined therapies are required for the the comprehensive management of temporomandibular …

85

Photobiomodulation Decreases Hyperalgesia in Complex Regional Pain Syndrome: An Experimental Mouse Model Subjected to Nicotine.

Rodrigues M, Cardoso RB, Kuriki HU, Marcolino AM, de Oliveira Guirro EC, Barbosa RI. Rodrigues M, et al. Lasers Surg Med. 2020 Nov;52(9):890-896. doi: 10.1002/lsm.23240. Epub 2020 Mar 22. Lasers Surg Med. 2020. PMID: 32201964

BACKGROUND AND OBJECTIVES: Complex regional pain syndrome (CRPS) is defined as an extreme and chronic pain condition, and photobiomodulation has relevance as a complementary treatment for CRPS. The objective of this study was to verify the effects of photo …

BACKGROUND AND OBJECTIVES: Complex regional pain syndrome (CRPS) is defined as an extreme and chronic pain condition, and p …

86

Effects of phototherapy on muscle activity and pain in individuals with temporomandibular disorder: a study protocol for a randomized controlled trial.

Herpich CM, Leal-Junior EC, Amaral AP, Tosato Jde P, Glória IP, Garcia MB, Barbosa BR, El Hage Y, Arruda ÉE, Gomes CÁ, Rodrigues MS, de Sousa DF, de Carvalho Pde T, Bussadori SK, Gonzalez Tde O, Politti F, Biasotto-Gonzalez DA. Herpich CM, et al. Trials. 2014 Dec 16;15:491. doi: 10.1186/1745-6215-15-491. Trials. 2014. PMID: 25514875 Free PMC article. Clinical Trial.

BACKGROUND: According to the International Association for the Study of Pain (IASP), the term temporomandibular disorder (TMD) regards a subgroup of orofacial pain, the symptoms of which include pain or discomfort in the temporomandibular joint, ears, …

BACKGROUND: According to the International Association for the Study of Pain (IASP), the term temporomandibular disorder (TMD) regard …

87

Photobiomodulation therapy for chronic knee pain in obese patients in pre-rehabilitation for bariatric surgery: randomised, placebo-controlled, double-blinded, clinical trial protocol.

Amorim ACFG, Belchior TCF, Silva Rodarte TND, Rebouças Junior FA, Rodrigues MFSD, Marcos RL, Lino-Dos-Santos-Franco A, Cecatto RB. Amorim ACFG, et al. BMJ Open. 2024 Jul 1;14(6):e079864. doi: 10.1136/bmjopen-2023-079864. BMJ Open. 2024. PMID: 38951012 Free PMC article.

As an analgesic therapy, photobiomodulation (PBM) has been studied with safety, efficacy, well-tolerated used and low costs. ...The PBM will be applied in bilateral knees and lumbar paraspinal points levels referring to the roots of innervation of the knee. The outc …

As an analgesic therapy, photobiomodulation (PBM) has been studied with safety, efficacy, well-tolerated used and low costs. . …

88

Increased Oral Health-Related Quality of Life Postsynergistic Treatment with Ultrasound and Photobiomodulation Therapy in Patients with Temporomandibular Disorders.

Panhóca VH, Bagnato VS, Alves N, Paolillo FR, Deana NF. Panhóca VH, et al. Photobiomodul Photomed Laser Surg. 2019 Nov;37(11):694-699. doi: 10.1089/photob.2019.4697. Epub 2019 Oct 7. Photobiomodul Photomed Laser Surg. 2019. PMID: 31589559

Background and objective: The object of this study was to analyze the oral health-related quality of life (OHRQoL) of patients with temporomandibular disorders (TMDs) who were treated simultaneously with ultrasound (US) and photobiomodulation therapy (PBMT). Materia …

Background and objective: The object of this study was to analyze the oral health-related quality of life (OHRQoL) of patients with temporom …

89

Effects of arthrocentesis and low-level laser therapy on patients with osteoarthritis of the temporomandibular joint.

Yanik S, Polat ME, Polat M. Yanik S, et al. Br J Oral Maxillofac Surg. 2021 Apr;59(3):347-352. doi: 10.1016/j.bjoms.2020.08.110. Epub 2020 Sep 5. Br J Oral Maxillofac Surg. 2021. PMID: 33280948

This retrospective study examined whether arthrocentesis combined with 10 sessions of low-level laser therapy (LLLT) improved the clinical outcomes of patients with temporomandibular joint osteoarthritis (TMJ-OA) compared with arthrocentesis alone. ... …

This retrospective study examined whether arthrocentesis combined with 10 sessions of low-level laser therapy (LLLT) im …

90

Effect of NIR laser therapy by MLS-MiS source against neuropathic pain in rats: in vivo and ex vivo analysis.

Micheli L, Cialdai F, Pacini A, Branca JJV, Morbidelli L, Ciccone V, Lucarini E, Ghelardini C, Monici M, Di Cesare Mannelli L. Micheli L, et al. Sci Rep. 2019 Jun 26;9(1):9297. doi: 10.1038/s41598-019-45469-5. Sci Rep. 2019. PMID: 31243320 Free PMC article.

The ineffectiveness and the frequent side effects of the drugs used to counteract neuropathic pain call for the discovery of new therapeutic strategies. Laser therapy proved to be effective for reducing pain sensitivity thus improving the quality of life. How …

The ineffectiveness and the frequent side effects of the drugs used to counteract neuropathic pain call for the discovery of new ther …

91

A Comparative Study of Low-Level Laser Therapy and Transcutaneous Electrical Nerve Stimulation as an Adjunct to Pharmaceutical Therapy for Myofascial Pain Dysfunction Syndrome: A Randomized Clinical Trial.

Mansourian A, Pourshahidi S, Sadrzadeh-Afshar MS, Ebrahimi H. Mansourian A, et al. Front Dent. 2019 Jul-Aug;16(4):256-264. doi: 10.18502/fid.v16i4.2084. Epub 2019 Aug 30. Front Dent. 2019. PMID: 32342054 Free PMC article.

This randomized clinical trial aimed to assess the efficacy of low-level laser therapy (LLLT) and transcutaneous electrical nerve stimulation (TENS) as an adjunct to pharmaceutical therapy for treatment of MPDS. ...The recovery rate was faster in the m …

This randomized clinical trial aimed to assess the efficacy of low-level laser therapy (LLLT) and transcutaneous electr …

92

Treatments for painful temporomandibular disc displacement with reduction: a network meta-analysis of randomized clinical trials.

Al-Moraissi EA, Almaweri AA, Al-Tairi NH, Alkhutari AS, Grillo R, Christidis N. Al-Moraissi EA, et al. Int J Oral Maxillofac Surg. 2024 Jan;53(1):45-56. doi: 10.1016/j.ijom.2023.09.006. Epub 2023 Oct 4. Int J Oral Maxillofac Surg. 2024. PMID: 37802670 Review.

The objective of this study was to compare and rank all treatments for DDwR, including conservative treatments, occlusal splints, low-level laser therapy (LLLT), manual therapy, no treatment (control), arthrocentesis (Arthro) alone, Arthro plus intra-a …

The objective of this study was to compare and rank all treatments for DDwR, including conservative treatments, occlusal splints, low …

93

Effects of low-level laser therapy on bone healing and signs of pain in dogs following tibial plateau leveling osteotomy.

Kennedy KC, Martinez SA, Martinez SE, Tucker RL, Davies NM. Kennedy KC, et al. Am J Vet Res. 2018 Aug;79(8):893-904. doi: 10.2460/ajvr.79.8.893. Am J Vet Res. 2018. PMID: 30058855 Free article.

OBJECTIVE To assess the effect of low-level laser therapy (LLLT) on markers of synovial inflammation and signs of pain, function, bone healing, and osteoarthritis following tibial plateau leveling osteotomy (TPLO) in dogs with spontaneous cranial cruci …

OBJECTIVE To assess the effect of low-level laser therapy (LLLT) on markers of synovial inflammation and signs of pa …

94

Comparison of low level laser, ultrasonic therapy and association in joint pain in Wistar rats.

Coradini JG, Mattjie TF, Bernardino GR, Peretti AL, Kakihata CM, Errero TK, Escher AR, Bertolini GR. Coradini JG, et al. Rev Bras Reumatol. 2014 Jan-Feb;54(1):7-12. Rev Bras Reumatol. 2014. PMID: 24878785 Free article. English, Portuguese.

INTRODUCTION: Both therapeutic ultrasound as a low level laser therapy are used to control musculoskeletal pain, despite controversy about its effects, yet the literature is poor and also presents conflicting results on possible cumulative effects of t …

INTRODUCTION: Both therapeutic ultrasound as a low level laser therapy are used to control musculoskeletal pain, …

95

Photobiomodulation therapy by NIR laser in persistent pain: an analytical study in the rat.

Micheli L, Di Cesare Mannelli L, Lucarini E, Cialdai F, Vignali L, Ghelardini C, Monici M. Micheli L, et al. Lasers Med Sci. 2017 Nov;32(8):1835-1846. doi: 10.1007/s10103-017-2284-9. Epub 2017 Jul 28. Lasers Med Sci. 2017. PMID: 28752263

In order to evaluate the pain relieving possibilities of photobiomodulation therapy (PBMT), we tested two near infrared (NIR) laser systems, with different power, against various kinds of persistent hyperalgesia animal models. ...In conclusion, this study sup …

In order to evaluate the pain relieving possibilities of photobiomodulation therapy (PBMT), we tested two near infrared …

96

Efficacy of low level laser therapy and intramuscular electrical stimulation on myofascial pain syndrome.

Sumen A, Sarsan A, Alkan H, Yildiz N, Ardic F. Sumen A, et al. J Back Musculoskelet Rehabil. 2015;28(1):153-8. doi: 10.3233/BMR-140503. J Back Musculoskelet Rehabil. 2015. PMID: 25061034

OBJECTIVES: We aimed to evaluate the efficacy of intramuscular electrical stimulation therapy (IMS) and low-level-lasertherapy (LLLT) in patients with MPS. METHODS: Patients were randomly divided into three groups. ...The patients were evaluated through the …

OBJECTIVES: We aimed to evaluate the efficacy of intramuscular electrical stimulation therapy (IMS) and low-level-laser …

97

Evaluation of the efficacy of a new low-level laser therapy home protocol in the treatment of temporomandibular joint disorder-related pain: A randomized, double-blind, placebo-controlled clinical trial.

Del Vecchio A, Floravanti M, Boccassini A, Gaimari G, Vestri A, Di Paolo C, Romeo U. Del Vecchio A, et al. Cranio. 2021 Mar;39(2):141-150. doi: 10.1080/08869634.2019.1599174. Epub 2019 Apr 19. Cranio. 2021. PMID: 30999823

Objective: This study analyzed a home, low-level laser therapy (LLLT) protocol to manage temporomandibular joint disorders (TMJDs)-related pain.Methods: Ninety TMJD patients (12M, 78F) between 18 and 73 years were randomly subdivided into three …

Objective: This study analyzed a home, low-level laser therapy (LLLT) protocol to manage temporomandibular joint …

98

Effects of superpulsed low-level laser therapy on temporomandibular joint pain.

Marini I, Gatto MR, Bonetti GA. Marini I, et al. Clin J Pain. 2010 Sep;26(7):611-6. doi: 10.1097/AJP.0b013e3181e0190d. Clin J Pain. 2010. PMID: 20664343 Clinical Trial.

OBJECTIVES: A randomized double-blind study was conducted to compare the efficacy of superpulsed low-level laser therapy (SLLLT) with nonsteroidal anti-inflammatory drugs in the treatment of pain caused by temporomandibular joint disorders. ...M …

OBJECTIVES: A randomized double-blind study was conducted to compare the efficacy of superpulsed low-level laser therapy …

99

Intravascular laser irradiation of blood as novel migraine treatment: an observational study.

Chen HH, Lin CY, Chen SJ, Huang WY, Kuo CW, Chang ST. Chen HH, et al. Eur J Med Res. 2023 Oct 25;28(1):457. doi: 10.1186/s40001-023-01438-3. Eur J Med Res. 2023. PMID: 37876003 Free PMC article.

Therefore, we evaluated the effect of low-level intravascular laser irradiation of blood (ILIB) therapy in patients with migraine. ...SPECT imaging showed a 1.27 0.27 fold increase in rCBF after ILIB treatment, and no significant differences in the rehabilita …

Therefore, we evaluated the effect of low-level intravascular laser irradiation of blood (ILIB) therapy in patients wit …

100

Comparison between Low-Level and High-Intensity Laser Therapy as an Adjunctive Treatment for Knee Osteoarthritis: A Randomized, Double-Blind Clinical Trial.

Ahmad MA, Moganan M, A Hamid MS, Sulaiman N, Moorthy U, Hasnan N, Yusof A. Ahmad MA, et al. Life (Basel). 2023 Jul 6;13(7):1519. doi: 10.3390/life13071519. Life (Basel). 2023. PMID: 37511894 Free PMC article.

BACKGROUND: Low-level (LLLT) and high-intensity laser therapy (HILT) can be beneficial additions to knee osteoarthritis (KOA) rehabilitation exercises; however, it is still being determined which electrophysical agent is more effective. ...The laser probe was …

BACKGROUND: Low-level (LLLT) and high-intensity laser therapy (HILT) can be beneficial additions to knee osteoarthritis …

101

Effect of low-level laser therapy on pain levels in patients with temporomandibular disorders: a systematic review.

Maia ML, Bonjardim LR, Quintans Jde S, Ribeiro MA, Maia LG, Conti PC. Maia ML, et al. J Appl Oral Sci. 2012 Nov-Dec;20(6):594-602. doi: 10.1590/s1678-77572012000600002. J Appl Oral Sci. 2012. PMID: 23329239 Free PMC article. Review.

Temporomandibular disorders (TMD) are characterized by the presence of temporomandibular joint (TMJ) and/or masticatory muscle pain and dysfunction. Low-level laser is presented as an adjuvant therapeutic modality for the treatment of TMD, especially w …

Temporomandibular disorders (TMD) are characterized by the presence of temporomandibular joint (TMJ) and/or masticatory muscle pai …

102

Acute effects of photobiomodulation applied on the dorsal root ganglion in gout model-induced rats.

Coracini CA, Zazula MF, Ferreira MO, da Silva JC, da Silva Scarton SR, Panis C, de Fátima Chasko Ribeiro L, da Silva Leal TS, Bertolini GRF. Coracini CA, et al. J Photochem Photobiol B. 2023 Feb;239:112644. doi: 10.1016/j.jphotobiol.2022.112644. Epub 2022 Dec 29. J Photochem Photobiol B. 2023. PMID: 36652793

Gouty arthritis is an inflammatory disease that triggers symptoms such as pain, swelling, and joint stiffness. Since its main therapy is medication, research on other forms of treatment that do not generate side effects is necessary. ...After analysing the re …

Gouty arthritis is an inflammatory disease that triggers symptoms such as pain, swelling, and joint stiffness. Since its main …

103

Interferential laser therapy in the treatment of shoulder pain and disability from musculoskeletal pathologies: a randomised comparative study.

Montes-Molina R, Prieto-Baquero A, Martínez-Rodríguez ME, Romojaro-Rodríguez AB, Gallego-Méndez V, Martínez-Ruiz F. Montes-Molina R, et al. Physiotherapy. 2012 Jun;98(2):143-50. doi: 10.1016/j.physio.2011.02.007. Epub 2011 May 28. Physiotherapy. 2012. PMID: 22507365 Clinical Trial.

OBJECTIVE: To test the safety of interferential laser therapy generated by two independent low level lasers and compare its effectiveness with conventional single laser therapy in the reduction of shoulder musculoskeletal pain and associated dis …

OBJECTIVE: To test the safety of interferential laser therapy generated by two independent low level lasers and compare …

104

Efficacy of laser therapy for temporomandibular disorders: A systematic review and meta-analysis.

Zhang Y, Qian Y, Huo K, Liu J, Huang X, Bao J. Zhang Y, et al. Complement Ther Med. 2023 Jun;74:102945. doi: 10.1016/j.ctim.2023.102945. Epub 2023 Mar 28. Complement Ther Med. 2023. PMID: 36997006 Free article. Review.

OBJECTIVE: The aim of this systematic review was to evaluate the efficacy of laser therapy in temporomandibular disorders (TMD). METHODS: Randomized controlled trials (RCTs) in regard to this issue were searched in electronic databases. ...However, there was no significant …

OBJECTIVE: The aim of this systematic review was to evaluate the efficacy of laser therapy in temporomandibular disorders (TMD). METH …

105

Current indications for low level laser treatment in maxillofacial surgery: a review.

Doeuk C, Hersant B, Bosc R, Lange F, SidAhmed-Mezi M, Bouhassira J, Meningaud JP. Doeuk C, et al. Br J Oral Maxillofac Surg. 2015 Apr;53(4):309-15. doi: 10.1016/j.bjoms.2015.02.005. Epub 2015 Mar 1. Br J Oral Maxillofac Surg. 2015. PMID: 25740083 Review.

Low level laser treatment (LLLT) is currently being used for various disorders, but with no convincing scientific evidence. ...We reviewed PubMed from January 2003 to January 2013 using the key phrase "low level laser treatment". Our inclusion criterio …

Low level laser treatment (LLLT) is currently being used for various disorders, but with no convincing scientific evidence. .. …

106

Low-level photodynamic therapy in chronic wounds.

Chen P, Zou Y, Liu Y, Han W, Zhang M, Wu Y, Yin R. Chen P, et al. Photodiagnosis Photodyn Ther. 2024 Apr;46:104085. doi: 10.1016/j.pdpdt.2024.104085. Epub 2024 Apr 11. Photodiagnosis Photodyn Ther. 2024. PMID: 38614272 Free article.

OBJECTIVE: To explore the efficacy and safety of photodynamic therapy (ALA-PDT) for the treatment of chronic infectious wounds. MATERIALS AND METHODS: ALA-PDT was used in ten patients with persistent wound infections and systemic complications who did not respond to conven …

OBJECTIVE: To explore the efficacy and safety of photodynamic therapy (ALA-PDT) for the treatment of chronic infectious wounds. MATER …

107

Effectiveness of conservative therapeutic modalities for temporomandibular disorders-related pain: a systematic review.

Tournavitis A, Sandris E, Theocharidou A, Slini T, Kokoti M, Koidis P, Tortopidis D. Tournavitis A, et al. Acta Odontol Scand. 2023 May;81(4):286-297. doi: 10.1080/00016357.2022.2138967. Epub 2022 Nov 10. Acta Odontol Scand. 2023. PMID: 36354093

Statistically significant differences were also detected between laser and photobiomodulation group and the control, in short-term treatment TMD-related pain. CONCLUSIONS: The primary findings of the present systematic review showed that the occlusal splint alone or …

Statistically significant differences were also detected between laser and photobiomodulation group and the control, in short-term tr …

108

Low level laser effects on pain to palpation and electromyographic activity in TMD patients: a double-blind, randomized, placebo-controlled study.

Venezian GC, da Silva MA, Mazzetto RG, Mazzetto MO. Venezian GC, et al. Cranio. 2010 Apr;28(2):84-91. doi: 10.1179/crn.2010.012. Cranio. 2010. PMID: 20491229 Clinical Trial.

With regard to the pain at palpation, although both groups presented a significant difference in the symptoms before and after the treatment, only the active doses showed statistically significant reductions in pain level in all the regions of the palpated muscles. …

With regard to the pain at palpation, although both groups presented a significant difference in the symptoms before and after the tr …

109

The reliability of using light therapy compared with LASER in pain reduction of temporomandibular disorders: a randomized controlled trial.

Al-Quisi AF, Jamil FA, Abdulhadi BN, Muhsen SJ. Al-Quisi AF, et al. BMC Oral Health. 2023 Feb 13;23(1):91. doi: 10.1186/s12903-023-02784-8. BMC Oral Health. 2023. PMID: 36782179 Free PMC article. Clinical Trial.

This study aimed to evaluate the efficacy of red LED light with low-level LASER in treating TMD patients. MATERIALS AND METHODS: A double-blind randomized clinical study was conducted and included 60 patients along 3 groups (20 for each group) presented with …

This study aimed to evaluate the efficacy of red LED light with low-level LASER in treating TMD patients. MATERIALS AND …

110

Comparative effectiveness of low-level laser therapy and transcutaneous electrical nerve stimulation in symptomatic Temporomandibular Disorders: A Randomised Control Trial.

Batra S, Srivastava A, Shivakumar GC, Marrapodi MM, Herford AS, Cicciù M, Minervini G. Batra S, et al. J Oral Rehabil. 2023 Nov;50(11):1185-1193. doi: 10.1111/joor.13555. Epub 2023 Jul 18. J Oral Rehabil. 2023. Retraction in: J Oral Rehabil. 2024 Sep;51(9):1934. doi: 10.1111/joor.13766. PMID: 37408297 Retracted. Clinical Trial.

BACKGROUND: Myofascial pain is one of the most common facial region pains, presenting itself with various signs and symptoms like tenderness of masticatory muscles and difficulty in mouth opening. ...OBJECTIVE: The aim of this study is to compare the effectiveness of trans …

BACKGROUND: Myofascial pain is one of the most common facial region pains, presenting itself with various signs and symptoms like ten …

111

Adjunctive use of combination of super-pulsed laser and light-emitting diodes phototherapy on nonspecific knee pain: double-blinded randomized placebo-controlled trial.

Leal-Junior EC, Johnson DS, Saltmarche A, Demchak T. Leal-Junior EC, et al. Lasers Med Sci. 2014 Nov;29(6):1839-47. doi: 10.1007/s10103-014-1592-6. Epub 2014 May 21. Lasers Med Sci. 2014. PMID: 24844921 Clinical Trial.

Phototherapy with low-level laser therapy (LLLT) and light-emitting diode therapy (LEDT) has arisen as an interesting alternative to drugs in treatments of musculoskeletal disorders. ...With this perspective in mind, this study aimed to investig …

Phototherapy with low-level laser therapy (LLLT) and light-emitting diode therapy (LEDT) has arisen as an …

112

A randomized double-blinded controlled trial on the effects of photobiomodulation therapy in dogs with osteoarthritis.

Alves JC, Santos A, Jorge P, Carreira LM. Alves JC, et al. Am J Vet Res. 2022 Jun 28;83(8):ajvr.22.03.0036. doi: 10.2460/ajvr.22.03.0036. Am J Vet Res. 2022. PMID: 35895799 Free article.

OBJECTIVE: To evaluate photobiomodulation therapy in dogs with bilateral hip osteoarthritis. ANIMALS: 20 dogs. PROCEDURES: Forty joints were assigned to a control group (CG; n = 20) or treatment group (photobiomodulation therapy [PBMT]; 20). CG receive …

OBJECTIVE: To evaluate photobiomodulation therapy in dogs with bilateral hip osteoarthritis. ANIMALS: 20 dogs. PROCEDURES: For …

113

Low-level laser-aided orthodontic treatment of periodontally compromised patients: a randomised controlled trial.

Ren C, McGrath C, Gu M, Jin L, Zhang C, Sum FHKMH, Wong KWF, Chau ACM, Yang Y. Ren C, et al. Lasers Med Sci. 2020 Apr;35(3):729-739. doi: 10.1007/s10103-019-02923-0. Epub 2019 Dec 12. Lasers Med Sci. 2020. PMID: 31833004 Clinical Trial.

Low-level laser irradiation (LLLI) shows effects in orthodontic pain relief and periodontal inflammation control. ...However, no intergroup difference was detected in the bacteria levels. Low-level laser irradiation exhibits benefits in pain …

Low-level laser irradiation (LLLI) shows effects in orthodontic pain relief and periodontal inflammation control. ...Ho …

114

Effect of photobiomodulation on alleviating primary dysmenorrhea caused by PGF(2alpha).

Fu Q, Yang J, Jiang H, Lin S, Qin H, Zhao J, Wang Y, Liu M. Fu Q, et al. J Biophotonics. 2024 May;17(5):e202300448. doi: 10.1002/jbio.202300448. Epub 2024 Feb 13. J Biophotonics. 2024. PMID: 38348528

Photobiomodulation (PBM) has attracted widespread attention in suppressing various pain and inflammation. ...Then to explore the underlying biological mechanisms of red light PBM on PD, we irradiated prostaglandin-F(2alpha) induced HUSM cells and found that …

Photobiomodulation (PBM) has attracted widespread attention in suppressing various pain and inflammation. ...Then to explore t …

115

Low level laser therapy for painful joints.

Momenzadeh S. Momenzadeh S. J Lasers Med Sci. 2013 Spring;4(2):67-9. J Lasers Med Sci. 2013. PMID: 25606309 Free PMC article. Review.

Low Level Laser Therapy (LLLT) uses a light source that generates extremely pure light, of a single wavelength(1). ...

Low Level Laser Therapy (LLLT) uses a light source that generates extremely pure light, of a single wavel …

116

Effectiveness of rehabilitation for patients with subacromial impingement syndrome: a systematic review.

Michener LA, Walsworth MK, Burnet EN. Michener LA, et al. J Hand Ther. 2004 Apr-Jun;17(2):152-64. doi: 10.1197/j.jht.2004.02.004. J Hand Ther. 2004. PMID: 15162102 Review.

Prior systematic reviews of rehabilitation for nondescript shoulder pain have not yielded clinically applicable results for those patients with subacromial impingement syndrome (SAIS). ...The limited evidence currently available suggests that exercise and joint mobi …

Prior systematic reviews of rehabilitation for nondescript shoulder pain have not yielded clinically applicable results for those pat …

117

Photobiomodulation-induced analgesia in experimental temporomandibular disorder involves central inhibition of fractalkine.

Ferrara-Jr JI, de Souza ET, Franciosi AC, Toniolo EF, Dale CS. Ferrara-Jr JI, et al. Lasers Med Sci. 2019 Dec;34(9):1841-1847. doi: 10.1007/s10103-019-02785-6. Epub 2019 Apr 10. Lasers Med Sci. 2019. PMID: 30969378

Treatments for TMD pain relief and control should be minimally invasive, reversible, and conservative. Photobiomodulation (PBM) is a promising option once it is known to inhibit inflammatory response and to relief painful symptoms. ...These data provide new insights …

Treatments for TMD pain relief and control should be minimally invasive, reversible, and conservative. Photobiomodulation (PBM …

118

Shoulder pain.

Speed C. Speed C. Clin Evid. 2005 Dec;(14):1543-60. Clin Evid. 2005. PMID: 16620462 Review. No abstract available.

119

Comparison of therapeutic effects of 940 nm diode laser acupuncture with transcutaneous electrical nerve stimulation in the myofascial pain dysfunction syndrome: a comparative randomized clinical trial.

Palizgir R, Najafi S, Modiri F, Sheykhbahaei N, Hakimiha N, Rahmanpour R. Palizgir R, et al. Lasers Med Sci. 2023 Oct 13;38(1):233. doi: 10.1007/s10103-023-03900-4. Lasers Med Sci. 2023. PMID: 37831208 Clinical Trial.

Myofascial pain dysfunction syndrome (MPDS) is one of the most common sources of orofacial pain. ...In this randomized clinical trial, 22 MPDS patients were randomly assigned to TENS (180 HZ, 300 s, 20 min) and LA (940 nm, continuous wave, 0. 5 w, 40 s, 105 J/cm2) g …

Myofascial pain dysfunction syndrome (MPDS) is one of the most common sources of orofacial pain. ...In this randomized clinica …

120

Efficacy of low-level laser therapy combined with exercise for subacromial impingement syndrome: A randomised controlled trial.

Alfredo PP, Bjordal JM, Junior WS, Marques AP, Casarotto RA. Alfredo PP, et al. Clin Rehabil. 2021 Jun;35(6):851-860. doi: 10.1177/0269215520980984. Epub 2020 Dec 14. Clin Rehabil. 2021. PMID: 33307783 Clinical Trial.

OBJECTIVE: To investigate the effect of low-level laser therapy (LLLT) combined with exercise on shoulder pain and disability in patients with subacromial impingement syndrome (SIS). ...INTERVENTION: Groups I (n = 42), II (n = 42) and III (n = 36) were …

OBJECTIVE: To investigate the effect of low-level laser therapy (LLLT) combined with exercise on shoulder pain a …

121

A systematic review with procedural assessments and meta-analysis of low level laser therapy in lateral elbow tendinopathy (tennis elbow).

Bjordal JM, Lopes-Martins RA, Joensen J, Couppe C, Ljunggren AE, Stergioulas A, Johnson MI. Bjordal JM, et al. BMC Musculoskelet Disord. 2008 May 29;9:75. doi: 10.1186/1471-2474-9-75. BMC Musculoskelet Disord. 2008. PMID: 18510742 Free PMC article. Review.

BACKGROUND: Recent reviews have indicated that low level level laser therapy (LLLT) is ineffective in lateral elbow tendinopathy (LET) without assessing validity of treatment procedures and doses or the influence of prior steroid injections. ...Ten of the tri …

BACKGROUND: Recent reviews have indicated that low level level laser therapy (LLLT) is ineffective in lateral elbow ten …

122

LLLT for the management of patients with ankylosing spondylitis.

Stasinopoulos D, Papadopoulos K, Lamnisos D, Stergioulas A. Stasinopoulos D, et al. Lasers Med Sci. 2016 Apr;31(3):459-69. doi: 10.1007/s10103-016-1874-2. Epub 2016 Jan 21. Lasers Med Sci. 2016. PMID: 26796709 Clinical Trial.

This study aimed to compare the effectiveness of the combined low-level laser therapy (LLLT) and passive stretching with combined placebo LLLT laser and the same passive stretching exercises in patients suffering from alphankylosing spondylitis. ...Group A re …

This study aimed to compare the effectiveness of the combined low-level laser therapy (LLLT) and passive stretching wit …

123

The use of LED therapy to treat synovial joints disorders: scoping review.

Coracini CA, Dos Santos Soares F, Bertolini GRF. Coracini CA, et al. Lasers Med Sci. 2022 Mar;37(2):701-721. doi: 10.1007/s10103-021-03372-4. Epub 2021 Jul 14. Lasers Med Sci. 2022. PMID: 34258669

The aim of this scoping review was to assess the extent of the literature on the use of LED therapy to treat synovial joint disorders. The JBI methodology for scoping reviews was followed. ...To be included, studies should have used LED as therapy, and includ …

The aim of this scoping review was to assess the extent of the literature on the use of LED therapy to treat synovial joint di …

124

Effects of different photobiomodulation dosimetries on temporomandibular dysfunction: a randomized, double-blind, placebo-controlled clinical trial.

Borges RMM, Cardoso DS, Flores BC, da Luz RD, Machado CR, Cerveira GP, Daitx RB, Dohnert MB. Borges RMM, et al. Lasers Med Sci. 2018 Dec;33(9):1859-1866. doi: 10.1007/s10103-018-2533-6. Epub 2018 May 30. Lasers Med Sci. 2018. PMID: 29850961 Clinical Trial.

The analgesic and anti-inflammatory effect produced by photobiomodulation has contributed to pain relief and functional improvement. However, the parameters to be used have not yet been well established. ...Pain, symptom severity, and joint mobility we …

The analgesic and anti-inflammatory effect produced by photobiomodulation has contributed to pain relief and functional improv …

125

Promising minimally invasive treatment modalities for symptomatic temporomandibular joint disc displacement with reduction: a randomized controlled clinical trial.

Rady NA, Bahgat MM, Abdel-Hamid AM. Rady NA, et al. BMC Oral Health. 2022 Dec 1;22(1):547. doi: 10.1186/s12903-022-02579-3. BMC Oral Health. 2022. PMID: 36456937 Free PMC article. Clinical Trial.

This prospective randomized controlled trial (RCT) was conducted to evaluate the effectiveness of botulinum toxin type-A (BTX-A) and low level laser therapy (LLLT) in comparison to anterior repositioning appliance (ARA) for the treatment of DDwR. ...CONCLUSIO …

This prospective randomized controlled trial (RCT) was conducted to evaluate the effectiveness of botulinum toxin type-A (BTX-A) and low …

126

Treatment of myofascial pain with a rapid laser therapy protocol compared to occlusal splint: A double-blind, randomized clinical trial.

Maracci LM, Stasiak G, de Oliveira Chami V, Franciscatto GJ, Milanesi J, Figueiró C, Bernardon Silva T, Guimarães MB, Marquezan M. Maracci LM, et al. Cranio. 2022 Sep;40(5):433-439. doi: 10.1080/08869634.2020.1773661. Epub 2020 Jun 3. Cranio. 2022. PMID: 32491964

OBJECTIVE: To compare the effect of a rapid low-level laser therapy (LLLT) protocol to Michigan occlusal splint in the treatment of myofascial pain, as well as to evaluate their impact on Oral Health-Related Quality of Life (OHRQoL). ...LLLT and placeb …

OBJECTIVE: To compare the effect of a rapid low-level laser therapy (LLLT) protocol to Michigan occlusal splint in the …

127

Effectiveness of nonpharmacological and nonsurgical interventions for patients with rheumatoid arthritis: an overview of systematic reviews.

Christie A, Jamtvedt G, Dahm KT, Moe RH, Haavardsholm EA, Hagen KB. Christie A, et al. Phys Ther. 2007 Dec;87(12):1697-715. doi: 10.2522/ptj.20070039. Epub 2007 Sep 25. Phys Ther. 2007. PMID: 17906290 Review.

Methodological quality was independently assessed by 2 authors, and the quality of evidence was summarized by explicit methods. Pain, function, and patient global assessment were considered primary outcomes of interest. ...High-quality evidence was found for beneficial eff …

Methodological quality was independently assessed by 2 authors, and the quality of evidence was summarized by explicit methods. Pain, …

128

Follow-up results of a randomized clinical trial for low-level laser therapy in painful TMD of muscular origins.

Magri LV, Bataglion C, Leite-Panissi CRA. Magri LV, et al. Cranio. 2021 Nov;39(6):502-509. doi: 10.1080/08869634.2019.1673588. Epub 2019 Oct 4. Cranio. 2021. PMID: 31585522 Clinical Trial.

After one year, the groups showed similar pain. Active LLLT was more effective in reducing pain palpation (p = .001) and referred pain (p = .04) in the region of the TMJs. ...Information about the treatment impairs the subjective perception of pain....

After one year, the groups showed similar pain. Active LLLT was more effective in reducing pain palpation (p = .001) and refer …

129

Effect of low-level gallium aluminum arsenide laser therapy on the chewing performance and pain perception of patients with systemic lupus erythematosus: A randomized controlled clinical trial.

Benli M, Huck O, Özcan M. Benli M, et al. Cranio. 2024 Jul;42(4):411-420. doi: 10.1080/08869634.2021.1971888. Epub 2021 Aug 29. Cranio. 2024. PMID: 34455912 Clinical Trial.

OBJECTIVE: To evaluate the effect of low-level laser therapy (LLLT) on pain intensity (PI) and chewing performance (CP) in systemic lupus erythematosus (SLE) patients with myogenic temporomandibular disorder (TMD). ...CONCLUSION: LLLT was an effective …

OBJECTIVE: To evaluate the effect of low-level laser therapy (LLLT) on pain intensity (PI) and chewing performan …

130

Evaluation of anti-nociceptive and anti-inflammatory activity of low-level laser therapy on temporomandibular joint inflammation in rodents.

Barretto SR, de Melo GC, dos Santos JC, de Oliveira MG, Pereira-Filho RN, Alves AV, Ribeiro MA, Lima-Verde IB, Quintans Júnior LJ, de Albuquerque-Júnior RL, Bonjardim LR. Barretto SR, et al. J Photochem Photobiol B. 2013 Dec 5;129:135-42. doi: 10.1016/j.jphotobiol.2013.10.002. Epub 2013 Oct 18. J Photochem Photobiol B. 2013. PMID: 24231378

The aim of this study was to investigate the analgesic and anti-inflammatory activity of low-level laser therapy (LLLT) on the nociceptive behavioral as well as histomorphological aspects induced by injection of formalin and carrageenan into the rat temporoma …

The aim of this study was to investigate the analgesic and anti-inflammatory activity of low-level laser therapy (LLLT) …

131

Laser acupuncture to reduce temporomandibular disorder (TMD) symptoms: systematic review and meta-analysis.

da Silva Mira PC, Biagini ACSCF, Gomes MG, Galo R, Corona SAM, Borsatto MC. da Silva Mira PC, et al. Lasers Med Sci. 2024 Feb 20;39(1):66. doi: 10.1007/s10103-024-03999-z. Lasers Med Sci. 2024. PMID: 38374226 Review.

The application of low-level laser therapy (LLLT) to acupuncture points may produce effects similar to that of needle stimulation in patients with temporomandibular disorders (TMD). ...The applied wavelengths ranged from 690 to 810 nm without significant vari …

The application of low-level laser therapy (LLLT) to acupuncture points may produce effects similar to that of needle s …

132

Effects of different energy density low-level laser therapies for temporomandibular joint disorders patients: a systematic review and network meta-analysis of parallel randomized controlled trials.

Jing G, Zhao Y, Dong F, Zhang P, Ren H, Liu J, Liu Y, Yu C, Hu J, Bao G, Kang H. Jing G, et al. Lasers Med Sci. 2021 Jul;36(5):1101-1108. doi: 10.1007/s10103-020-03197-7. Epub 2020 Nov 23. Lasers Med Sci. 2021. PMID: 33230581

Immediately after treatment, the d1 laser therapy (energy density ranging from 0 to 10 J/cm(2)) ranked first. The d1 laser therapy showed more pain reduction than placebo ( MD = 2.49, 95% CI ranging from 1.28 to 3.71). ...CONCLUSIONS: For clinical application …

Immediately after treatment, the d1 laser therapy (energy density ranging from 0 to 10 J/cm(2)) ranked first. The d1 laser therapy …

133

Measurements of jaw movements and TMJ pain intensity in patients treated with GaAlAs laser.

Mazzetto MO, Hotta TH, Pizzo RC. Mazzetto MO, et al. Braz Dent J. 2010;21(4):356-60. doi: 10.1590/s0103-64402010000400012. Braz Dent J. 2010. PMID: 20976388 Free article. Clinical Trial.

The aim of this study was to evaluate the effectiveness of low-level laser therapy (LLLT) on the improvement of the mandibular movements and painful symptoms in individuals with temporomandibular disorders (TMD). ...A significant improvement in the range of m …

The aim of this study was to evaluate the effectiveness of low-level laser therapy (LLLT) on the improvement of the man …

134

Low-energy laser therapy application on knee joints as an auxiliary treatment in patients with polyarticular juvenile idiopathic arthritis: a dual-arm randomized clinical trial.

Elnaggar RK, Mahmoud WS, Abdelbasset WK, Alqahtani BA, Alrawaili SM, Elfakharany MS. Elnaggar RK, et al. Lasers Med Sci. 2022 Apr;37(3):1737-1746. doi: 10.1007/s10103-021-03427-6. Epub 2021 Oct 2. Lasers Med Sci. 2022. PMID: 34599401 Clinical Trial.

Patients with juvenile idiopathic arthritis (JIA) always experience persistent pain and stiffness which induces muscle weakness, fatigue, and functional limitations. This study evaluated whether applying low-energy laser therapy (LLT) on the knee joint could …

Patients with juvenile idiopathic arthritis (JIA) always experience persistent pain and stiffness which induces muscle weakness, fati …

135

Efficacy of rehabilitative therapies on otologic symptoms in patients with temporomandibular disorders: A systematic review of randomised controlled trials.

Ferrillo M, Marotta N, Viola P, Chiarella G, Fortunato L, Ammendolia A, Giudice A, de Sire A. Ferrillo M, et al. J Oral Rehabil. 2024 Aug;51(8):1621-1631. doi: 10.1111/joor.13716. Epub 2024 Apr 29. J Oral Rehabil. 2024. PMID: 38685701 Review.

BACKGROUND: The term temporomandibular disorder (TMD) indicates a set of musculoskeletal conditions involving temporomandibular joint (TMJ), masticatory musculature, and related anatomical structures. Pain is the most common clinical manifestation of TMD, and the au …

BACKGROUND: The term temporomandibular disorder (TMD) indicates a set of musculoskeletal conditions involving temporomandibular joint …

136

Treatment of painful temporomandibular joint disc displacement without reduction: network meta-analysis of randomized clinical trials.

Al-Moraissi EA, Al-Otaibi K, Almaweri AA, Bastos RM, Haas Junior OL, Amran AG. Al-Moraissi EA, et al. Int J Oral Maxillofac Surg. 2024 Jul;53(7):584-595. doi: 10.1016/j.ijom.2024.02.004. Epub 2024 Feb 23. Int J Oral Maxillofac Surg. 2024. PMID: 38395688 Review.

The objective of this study was to compare and rank all treatments for DDwoR, including conservative treatments, occlusal splints, low-level laser therapy (LLLT), arthrocentesis (Arthro) alone, Arthro plus intra-articular injection (IAI) of platelet-rich plas …

The objective of this study was to compare and rank all treatments for DDwoR, including conservative treatments, occlusal splints, low …

137

Effects of photobiomodulation combined with orofacial myofunctional therapy on the quality of life of individuals with temporomandibular disorder.

Dias WCFGDS, Cavalcanti RVA, Magalhães Júnior HV, Pernambuco LA, Alves GÂDS. Dias WCFGDS, et al. Codas. 2022 Apr 8;34(5):e20200313. doi: 10.1590/2317-1782/20212020313. eCollection 2022. Codas. 2022. PMID: 35416889 Free PMC article. Clinical Trial.

PURPOSE: To analyze the impact of photobiomodulation combined with orofacial myofunctional therapy (OMT) on the oral health quality of life (OHQOL) of individuals with temporomandibular disorder, before and after the treatment. ...There was a strong positive correla …

PURPOSE: To analyze the impact of photobiomodulation combined with orofacial myofunctional therapy (OMT) on the oral health qu …

138

Can the severity of orofacial myofunctional conditions interfere with the response of analgesia promoted by active or placebo low-level laser therapy?

Rodrigues CA DDS, MS, PhD, Melchior MO SLPs, MS, Valencise Magri L DDS, MS, PhD, Mazzetto MO DDS, MS, PhD. Rodrigues CA DDS, MS, PhD, et al. Cranio. 2020 Jul;38(4):240-247. doi: 10.1080/08869634.2018.1520950. Epub 2018 Sep 23. Cranio. 2020. PMID: 30244669 Clinical Trial.

OBJECTIVE: To analyze the influence of orofacial myofunctional condition (OMC) on pain perception, temporomandibular disorders (TMD) severity, and the response to low-level laser therapy (LLLT) in women with painful TMD. ...RESULTS: No correlation was …

OBJECTIVE: To analyze the influence of orofacial myofunctional condition (OMC) on pain perception, temporomandibular disorders (TMD) …

139

Exploring the efficacy of low-level laser therapy and exercise for knee osteoarthritis.

Kholvadia A, Constantinou D, Gradidge PJ. Kholvadia A, et al. S Afr J Sports Med. 2019 Jan 1;31(1):v31i1a6058. doi: 10.17159/2078-516X/2019/v31i1a6058. eCollection 2019. S Afr J Sports Med. 2019. PMID: 36817986 Free PMC article.

OBJECTIVE: The purpose of this study was to determine the effect of low-level laser therapy (LLLT) in the treatment of knee osteoarthritis (KOA). A randomised controlled trial (RCT) was conducted on 111 participants (aged between 40-75 years) diagnosed with K …

OBJECTIVE: The purpose of this study was to determine the effect of low-level laser therapy (LLLT) in the treatment of …

140

Low-level laser therapy for management of TMJ osteoarthritis.

Madani AS, Ahrari F, Nasiri F, Abtahi M, Tunér J. Madani AS, et al. Cranio. 2014 Jan;32(1):38-44. doi: 10.1179/0886963413Z.0000000004. Cranio. 2014. PMID: 24660645 Clinical Trial.

AIMS: This study investigated the efficacy of low-level laser therapy (LLLT) for the management of temporomandibular joint (TMJ) osteoarthritis. ...The patients were evaluated before laser therapy (T1), after 6 (T2) and 12 (T3) laser application …

AIMS: This study investigated the efficacy of low-level laser therapy (LLLT) for the management of temporomandibular …

141

Class IV laser therapy for trapeziometacarpal joint osteoarthritis: Study protocol for a randomized placebo-controlled trial.

Medina-Porqueres I, Cantero-Tellez R. Medina-Porqueres I, et al. Physiother Res Int. 2018 Apr;23(2):e1706. doi: 10.1002/pri.1706. Epub 2018 Mar 9. Physiother Res Int. 2018. PMID: 29520953 Clinical Trial.

The aim of the proposed study is to assess the effect of Class IV laser therapy (LT) on pain and pinch strength in patients with thumb carpometacarpal (TCMC) OA. ...Patients with TCMC-OA will be randomly assigned to the experimental group (will receive LT) and contr …

The aim of the proposed study is to assess the effect of Class IV laser therapy (LT) on pain and pinch strength in patients wi …

142

Photomodulation in the treatment of chronic pain in patients with temporomandibular disorder: protocol for cost-effectiveness analysis.

Sobral APT, Godoy CLH, Fernandes KPS, Bussadori SK, Ferrari RAM, Horliana ACRT, Monken SF, Motta LJ. Sobral APT, et al. BMJ Open. 2018 May 5;8(5):e018326. doi: 10.1136/bmjopen-2017-018326. BMJ Open. 2018. PMID: 29730613 Free PMC article.

The present study aims to estimate the direct costs for treatment of chronic muscle pain with photobiomodulation therapy, occlusal splint and placebo in patients with TMD; to evaluate the effectiveness of photobiomodulation therapy and occlusal …

The present study aims to estimate the direct costs for treatment of chronic muscle pain with photobiomodulation therapy …

143

WITHDRAWN: Low level laser therapy (Classes III) for treating osteoarthritis.

Brosseau L, Robinson V, Wells G, Debie R, Gam A, Harman K, Morin M, Shea B, Tugwell P. Brosseau L, et al. Cochrane Database Syst Rev. 2007 Jul 18;(1):CD002046. doi: 10.1002/14651858.CD002046.pub3. Cochrane Database Syst Rev. 2007. PMID: 17636694 Review.

BACKGROUND: Osteoarthritis (OA) affects a large portion of the population. Low Level Laser Therapy (LLLT) is a light source that generates extremely pure light, of a single wavelength. ...One trial evaluated the effectiveness of laser treatment …

BACKGROUND: Osteoarthritis (OA) affects a large portion of the population. Low Level Laser Therapy (LLLT) is a light …

144

Low level laser therapy (Classes I, II and III) for treating osteoarthritis.

Brosseau L, Welch V, Wells G, deBie R, Gam A, Harman K, Morin M, Shea B, Tugwell P. Brosseau L, et al. Cochrane Database Syst Rev. 2003;(2):CD002046. doi: 10.1002/14651858.CD002046. Cochrane Database Syst Rev. 2003. Update in: Cochrane Database Syst Rev. 2004;(3):CD002046. doi: 10.1002/14651858.CD002046.pub2. PMID: 12804422 Updated. Review.

BACKGROUND: Osteoarthritis (OA) affects a large proportion of the population. Low Level Laser Therapy (LLLT) is a light source that generates extremely pure light, of a single wavelength. ...Other outcomes of joint tenderness, joint …

BACKGROUND: Osteoarthritis (OA) affects a large proportion of the population. Low Level Laser Therapy (LLLT) is a li …

145

The analgesic effect of photobiomodulation therapy (830 nm) on the masticatory muscles: a randomized, double-blind study.

Costa SAP, Florezi GP, Artes GE, Costa JRD, Gallo RT, Freitas PM, Witzel AL. Costa SAP, et al. Braz Oral Res. 2017 Dec 18;31:e107. doi: 10.1590/1807-3107bor-2017.vol31.0107. Braz Oral Res. 2017. PMID: 29267668 Free article. Clinical Trial.

This study assesses the efficacy of photobiomodulation therapy (830 nm) for myalgia treatment of masticatory muscles. Sixty patients with muscular myalgia were selected and randomly allocated into 2 groups (n=30): Group A comprised patients given a placebo (control) …

This study assesses the efficacy of photobiomodulation therapy (830 nm) for myalgia treatment of masticatory muscles. Sixty pa …

146

Monochromatic Infrared Photo Energy versus Low Level Laser Therapy in Patients with Knee Osteoarthritis.

Ammar TA. Ammar TA. J Lasers Med Sci. 2014 Fall;5(4):176-82. J Lasers Med Sci. 2014. PMID: 25653818 Free PMC article.

INTRODUCTION: Knee osteoarthritis (KO) is the most common joint disease for which there is no optimal treatment. Monochromatic infrared photo energy (MIPE) is a relatively new light modality used to reduce pain and increase circulation. Low Level …

INTRODUCTION: Knee osteoarthritis (KO) is the most common joint disease for which there is no optimal treatment. Monochromatic infrar …

147

Low level laser therapy (Classes I, II and III) for treating osteoarthritis.

Brosseau L, Welch V, Wells G, DeBie R, Gam A, Harman K, Morin M, Shea B, Tugwell P. Brosseau L, et al. Cochrane Database Syst Rev. 2004;(3):CD002046. doi: 10.1002/14651858.CD002046.pub2. Cochrane Database Syst Rev. 2004. Update in: Cochrane Database Syst Rev. 2007 Jul 18;(1):CD002046. doi: 10.1002/14651858.CD002046.pub3. PMID: 15266461 Updated. Review.

BACKGROUND: Osteoarthritis (OA) affects a large proportion of the population. Low Level Laser Therapy (LLLT) is a light source that generates extremely pure light, of a single wavelength. ...Only one study found significant results for increased …

BACKGROUND: Osteoarthritis (OA) affects a large proportion of the population. Low Level Laser Therapy (LLLT) is a li …

148

A Randomized Controlled Trial Evaluating the Levels of the Biomarkers hs-CRP, IL-6, and IL-8 in Patients with Temporomandibular Disorder Treated with LLLT, Traditional Conservative Treatment, and a Combination of Both.

Zwiri AM, Ahmad WMAW, Asif JA, Phaik KS, Husein A, Kassim NK, Ab-Ghani Z. Zwiri AM, et al. Int J Environ Res Public Health. 2022 Jul 23;19(15):8987. doi: 10.3390/ijerph19158987. Int J Environ Res Public Health. 2022. PMID: 35897358 Free PMC article. Clinical Trial.

Temporomandibular disorders (TMDs) are a type of idiopathic orofacial pain. Inflammation, particularly elevated circulating levels of high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and interleukin-8 (IL-8), has been linked to pain symptoms. ...A …

Temporomandibular disorders (TMDs) are a type of idiopathic orofacial pain. Inflammation, particularly elevated circulating levels of …

149

Comparative efficacy of low-level laser therapy (LLLT) to TENS and therapeutic ultrasound in management of TMDs: a systematic review & meta-analysis.

Ansari S, Charantimath S, Lagali-Jirge V, Keluskar V. Ansari S, et al. Cranio. 2022 Mar 22:1-10. doi: 10.1080/08869634.2022.2050975. Online ahead of print. Cranio. 2022. PMID: 35315745

OBJECTIVE: To assess the reduction in pain, muscle tenderness, joint clicking, and improvement in mouth opening (MO) after low-level laser therapy (LLLT) compared to transcutaneous electrical nerve stimulation (TENS) and therapeutic ultrasound ( …

OBJECTIVE: To assess the reduction in pain, muscle tenderness, joint clicking, and improvement in mouth opening (MO) after …

150

Low level laser therapy (classes I, II and III) for the treatment of osteoarthritis.

Brosseau L, Welch V, Wells G, deBie R, Gam A, Harman K, Morin M, Shea B, Tugwell P. Brosseau L, et al. Cochrane Database Syst Rev. 2000;(2):CD002046. doi: 10.1002/14651858.CD002046. Cochrane Database Syst Rev. 2000. Update in: Cochrane Database Syst Rev. 2003;(2):CD002046. doi: 10.1002/14651858.CD002046. PMID: 10796460 Updated. Review.

BACKGROUND: Osteoarthritis (OA) affects a large proportion of the population. Low Level Laser Therapy (LLLT) is a light source that generates extremely pure light, of a single wavelength. ...Other outcomes of joint tenderness, joint …

BACKGROUND: Osteoarthritis (OA) affects a large proportion of the population. Low Level Laser Therapy (LLLT) is a li …

151

What conservative interventions improve bite function in those with temporomandibular disorders? A systematic review using self-reported and physical measures.

Dinsdale A, Costin B, Dharamdasani S, Page R, Purs N, Treleaven J. Dinsdale A, et al. J Oral Rehabil. 2022 Apr;49(4):456-475. doi: 10.1111/joor.13307. Epub 2022 Feb 8. J Oral Rehabil. 2022. PMID: 35108410 Review.

Interventions included splinting, photobiomodulation, needling, exercise, manual therapy, and patient education, which were evaluated using mastication-related pain, self-reported chewing difficulty, and bite force/endurance outcome measures. Findings suggest …

Interventions included splinting, photobiomodulation, needling, exercise, manual therapy, and patient education, which were ev …

152

Photobiomodulation versus light-emitting diode (LED) therapy in the treatment of temporomandibular disorder: study protocol for a randomized, controlled clinical trial.

Langella LG, Silva PFC, Costa-Santos L, Gonçalves MLL, Motta LJ, Deana AM, Fernandes KPS, Mesquita-Ferrari RA, Bussadori SK. Langella LG, et al. Trials. 2018 Jan 26;19(1):71. doi: 10.1186/s13063-018-2444-7. Trials. 2018. PMID: 29373998 Free PMC article.

TMD can occur unilaterally or bilaterally and approximately 70% of the population is affected with at least one sign. The disorder progresses with orofacial pain, muscle pain involving the masticatory and cervical muscles, joint noises (clicks and pops), j …

TMD can occur unilaterally or bilaterally and approximately 70% of the population is affected with at least one sign. The disorder progresse …

153

Investigation of the effect of GaAs laser therapy on lateral epicondylitis.

Emanet SK, Altan LI, Yurtkuran M. Emanet SK, et al. Photomed Laser Surg. 2010 Jun;28(3):397-403. doi: 10.1089/pho.2009.2555. Photomed Laser Surg. 2010. PMID: 19877824 Clinical Trial.

BACKGROUND AND OBJECTIVE: There are conflicting reports regarding the efficacy of low energy laser therapy in treatment of lateral epicondylitis (LE). Contradictory results are considered to be due to different joint treatment protocols regarding variables such as d …

BACKGROUND AND OBJECTIVE: There are conflicting reports regarding the efficacy of low energy laser therapy in treatment of lateral ep …

154

Evaluation of Low-Level Laser Therapy in TMD Patients.

Ayyildiz S, Emir F, Sahin C. Ayyildiz S, et al. Case Rep Dent. 2015;2015:424213. doi: 10.1155/2015/424213. Epub 2015 Oct 26. Case Rep Dent. 2015. PMID: 26587294 Free PMC article.

Low-level laser therapy (LLLT) is suggested to have biostimulating and analgesic effects through direct irradiation without causing thermal response. ...First patient had a history of limited mouth opening and pain in temporomandibular joint (TM …

Low-level laser therapy (LLLT) is suggested to have biostimulating and analgesic effects through direct irradiation wit …

155

What is the clinical effectiveness and cost-effectiveness of conservative interventions for tendinopathy? An overview of systematic reviews of clinical effectiveness and systematic review of economic evaluations.

Long L, Briscoe S, Cooper C, Hyde C, Crathorne L. Long L, et al. Health Technol Assess. 2015 Jan;19(8):1-134. doi: 10.3310/hta19080. Health Technol Assess. 2015. PMID: 25629427 Free PMC article. Review.

BACKGROUND: Lateral elbow tendinopathy (LET) is a common complaint causing characteristic pain in the lateral elbow and upper forearm, and tenderness of the forearm extensor muscles. ...

BACKGROUND: Lateral elbow tendinopathy (LET) is a common complaint causing characteristic pain in the lateral elbow and upper forearm …

156

Laser Biophotomodulation in Patients with Neurosensory Disturbance of the Inferior Alveolar Nerve After Sagittal Split Ramus Osteotomy: A 2-Year Follow-Up Study.

Guarini D, Gracia B, Ramírez-Lobos V, Noguera-Pantoja A, Solé-Ventura P. Guarini D, et al. Photomed Laser Surg. 2018 Jan;36(1):3-9. doi: 10.1089/pho.2017.4312. Epub 2017 Oct 12. Photomed Laser Surg. 2018. PMID: 29022844

BACKGROUND: Photobiomodulation is a common clinical tool in dentistry, for its beneficial effects have been shown in surgical and periodontal wound healing, reducing of swelling and pain, neurosensory recovery, and treatment of temporomandibular joint disorde …

BACKGROUND: Photobiomodulation is a common clinical tool in dentistry, for its beneficial effects have been shown in surgical and per …

157

Immediate responses of multi-focal low level laser therapy on quadriceps in knee osteoarthritis patients.

Li CF, Chen YJ, Lin TY, Hsiao YH, Fu JC, Chen CH, Lee CL. Li CF, et al. Kaohsiung J Med Sci. 2019 Nov;35(11):702-707. doi: 10.1002/kjm2.12113. Epub 2019 Aug 7. Kaohsiung J Med Sci. 2019. PMID: 31390143 Free article.

Low-level laser therapy (LLLT) applying on knee osteoarthritis (OA) patients has shown positive outcomes in analgesic effect and functional recovery. ...The multi-focal LLLT significantly improved knee joint pain as measured by the NRS (54% redu …

Low-level laser therapy (LLLT) applying on knee osteoarthritis (OA) patients has shown positive outcomes in analgesic e …

158

Piroxicam and laser phototherapy in the treatment of TMJ arthralgia: a double-blind randomised controlled trial.

de Carli ML, Guerra MB, Nunes TB, di Matteo RC, de Luca CE, Aranha AC, Bolzan MC, Witzel AL. de Carli ML, et al. J Oral Rehabil. 2013 Mar;40(3):171-8. doi: 10.1111/joor.12022. Epub 2012 Dec 17. J Oral Rehabil. 2013. PMID: 23252583 Clinical Trial.

This study aimed to evaluate the efficacy of piroxicam associated with low-level laser therapy compared with single therapies in 32 patients presenting temporomandibular joint arthralgia in a random and double-blind research design. ...The combi …

This study aimed to evaluate the efficacy of piroxicam associated with low-level laser therapy compared with single the …

159

The influence of educational measures and low-level laser phototherapy on temporomandibular disorders: Study protocol clinical trial (SPIRIT Compliant).

Dantas CMG, Vivan CL, de Fantini SM, de Freitas Costa E Silva PM, Pannuti CM, Witzel AL, Dominguez GC. Dantas CMG, et al. Medicine (Baltimore). 2020 Mar;99(10):e19005. doi: 10.1097/MD.0000000000019005. Medicine (Baltimore). 2020. PMID: 32150048 Free PMC article.

Photobiomodulation therapy (PBMT) with low-power laser is used for pain relief in several clinical conditions, including temporomandibular disorders (TMD). ...The effect of the proposed therapies will be measured by: pain reduction in VAS; pressure …

Photobiomodulation therapy (PBMT) with low-power laser is used for pain relief in several clinical conditions, includin …

160

Low-power laser treatment for shoulder pain.

Bingöl U, Altan L, Yurtkuran M. Bingöl U, et al. Photomed Laser Surg. 2005 Oct;23(5):459-64. doi: 10.1089/pho.2005.23.459. Photomed Laser Surg. 2005. PMID: 16262574 Clinical Trial.

OBJECTIVE: The objective of this study is to investigate the effect of low-power gallium-arsenide laser treatment on the patients with shoulder pain. BACKGROUND DATA: Low-energy laser therapy has recently been popularized in the treatment of various rheumatologic, n …

OBJECTIVE: The objective of this study is to investigate the effect of low-power gallium-arsenide laser treatment on the patients with shoul …

161

Low-level laser therapy: A novel therapeutic approach to temporomandibular disorder - A randomized, double-blinded, placebo-controlled trial.

Shobha R, Narayanan VS, Jagadish Pai BS, Jaishankar HP, Jijin MJ. Shobha R, et al. Indian J Dent Res. 2017 Jul-Aug;28(4):380-387. doi: 10.4103/ijdr.IJDR_345_15. Indian J Dent Res. 2017. PMID: 28836528 Free article. Clinical Trial.

AIMS AND OBJECTIVE: The objective of this study was to assess the effectiveness of low-level laser therapy (LLLT)/low intensity laser therapy (LILT) in the management of temporomandibular joint (TMJ) pain in a random and double-blind rese …

AIMS AND OBJECTIVE: The objective of this study was to assess the effectiveness of low-level laser therapy (LLLT)/low i …

162

Intra-Articular Laser Therapy May Be a Feasible Option in Treating Knee Osteoarthritis in Elderly Patients.

Chen JL, Hsu CC, Chen WCC, Peng YN, Chen CPC, Suputtitada A. Chen JL, et al. Biomed Res Int. 2022 Nov 22;2022:3683514. doi: 10.1155/2022/3683514. eCollection 2022. Biomed Res Int. 2022. PMID: 36457337 Free PMC article.

They are often troubled with altered knee function, such as pain and weakness. However, not all these patients are able to receive autologous platelet-rich plasma (PRP) injections as they may be taking antiplatelet or anticoagulant medications. ...In this study, 19 elderly …

They are often troubled with altered knee function, such as pain and weakness. However, not all these patients are able to receive au …

163

Effects of low-level laser therapy in combination with physiotherapy in the management of rotator cuff tendinitis.

Eslamian F, Shakouri SK, Ghojazadeh M, Nobari OE, Eftekharsadat B. Eslamian F, et al. Lasers Med Sci. 2012 Sep;27(5):951-8. doi: 10.1007/s10103-011-1001-3. Epub 2011 Nov 4. Lasers Med Sci. 2012. PMID: 22052627 Clinical Trial.

A total of 50 patients who were referred to the Physical Medicine and Rehabilitation Clinic with shoulder pain and rotator cuff disorders were selected. Pain severity measured with visual analogue scale (VAS), abduction, and external rotation range of motion in shou …

A total of 50 patients who were referred to the Physical Medicine and Rehabilitation Clinic with shoulder pain and rotator cuff disor …

164

Positive effects of low level laser therapy (LLLT) on Bouchard's and Heberden's osteoarthritis.

Baltzer AW, Ostapczuk MS, Stosch D. Baltzer AW, et al. Lasers Surg Med. 2016 Jul;48(5):498-504. doi: 10.1002/lsm.22480. Epub 2016 Feb 2. Lasers Surg Med. 2016. PMID: 26833862 Clinical Trial.

While research usually focuses on OA of the large joints, OA of the hand receives relatively little attention resulting in a lack of a therapeutic gold standard. Low level laser therapy (LLLT)/photobiomodulation therapy has been successfully use …

While research usually focuses on OA of the large joints, OA of the hand receives relatively little attention resulting in a lack of a thera …

165

Vascular photobiomodulation in the treatment of children with temporomandibular disorders: Study protocol for a randomized, controlled, blind, clinical trial.

Sertaje MRF, Gonçalves MLL, Gomes AO, Bruno LH, Fossati AL, Viarengo NO, Santos EM, Sobral APT, Mesquita-Ferrari RA, Fernandes KPS, Horliana ACRT, Motta LJ, Bussadori SK. Sertaje MRF, et al. Medicine (Baltimore). 2022 Oct 21;101(42):e31228. doi: 10.1097/MD.0000000000031228. Medicine (Baltimore). 2022. PMID: 36281107 Free PMC article.

BACKGROUND: This study aims to verify if the use of intravascular laser irradiation of blood (ILIB) influences the reduction of pain and increases the range of motion in opening and closing of the mouth in children and adolescents with temporomandibular disorders (TMD). .. …

BACKGROUND: This study aims to verify if the use of intravascular laser irradiation of blood (ILIB) influences the reduction of pain …

166

Is low level laser effective for the treatment of orofacial pain?: A systematic review.

Tengrungsun T, Mitrirattanakul S, Buranaprasertsuk P, Suddhasthir T. Tengrungsun T, et al. Cranio. 2012 Oct;30(4):280-5. doi: 10.1179/crn.2012.042. Cranio. 2012. PMID: 23156969 Review.

The aim of this study was to assess the effectiveness of low level laser therapy (LLLT) as a treatment for orofacial pain considering the methodology of the studies. ...

The aim of this study was to assess the effectiveness of low level laser therapy (LLLT) as a treatment for orofacial …

167

The efficacy of low-level diode laser versus laser acupuncture for the treatment of myofascial pain dysfunction syndrome (MPDS).

Khalighi HR, Mortazavi H, Mojahedi SM, Azari-Marhabi S, Parvaie P, Anbari F. Khalighi HR, et al. J Dent Anesth Pain Med. 2022 Feb;22(1):19-27. doi: 10.17245/jdapm.2022.22.1.19. Epub 2022 Jan 24. J Dent Anesth Pain Med. 2022. PMID: 35169617 Free PMC article.

This study compared the efficacies of low-level diode laser therapy (LLLT) and laser acupuncture therapy (LAT) in the treatment of MPDS. ...Patients in the LLLT group received 12 sessions of low-level diode laser irradiation applied to th …

This study compared the efficacies of low-level diode laser therapy (LLLT) and laser acupuncture therapy (LAT) i …

168

Laser acupuncture for myofascial pain of the masticatory muscles. A controlled pilot study.

Katsoulis J, Ausfeld-Hafter B, Windecker-Gétaz I, Katsoulis K, Blagojevic N, Mericske-Stern R. Katsoulis J, et al. Schweiz Monatsschr Zahnmed. 2010;120(3):213-25. Schweiz Monatsschr Zahnmed. 2010. PMID: 20238281 Free article. Clinical Trial. English, German.

After three months a clinical follow-up was carried out, which included a standardised questionnaire as to the maximum pain intensity (VAS and verbal scale) and on the need for further treatment. A pain reduction (VAS) of about 50% was evaluated as a success. ...The …

After three months a clinical follow-up was carried out, which included a standardised questionnaire as to the maximum pain intensity …

169

Low-Level Laser Therapy for Thumb Carpometacarpal Joint Osteoarthritis: A Randomized Controlled Trial.

Rahman MM, Shakoor MA, Ferdous N, Alam MO, Farhad S, Mehedi ABM, Sarker S, Moyeenuzzaman M. Rahman MM, et al. Cureus. 2024 Apr 9;16(4):e57883. doi: 10.7759/cureus.57883. eCollection 2024 Apr. Cureus. 2024. PMID: 38725743 Free PMC article.

Background and aim Low-level laser therapy (LLLT) is considered a promising non-invasive treatment option for osteoarthritis (OA). ...Results The majority of patients diagnosed with CMC1 joint OA were in their fifties. At baseline, patients of both int …

Background and aim Low-level laser therapy (LLLT) is considered a promising non-invasive treatment option for osteoarth …

170

[Low level laser therapy : A narrative literature review on the efficacy in the treatment of rheumatic orthopaedic conditions].

Baltzer AWA, Stosch D, Seidel F, Ostapczuk MS. Baltzer AWA, et al. Z Rheumatol. 2017 Nov;76(9):806-812. doi: 10.1007/s00393-017-0309-1. Z Rheumatol. 2017. PMID: 28466181 Review. German.

BACKGROUND: In low level laser therapy (LLLT) low wattage lasers are used to irradiate the affected skin areas, joints, nerves, muscles and tendons without any sensation or thermal damage. ...RESULTS: While earlier studies often failed to demonstrate the effi …

BACKGROUND: In low level laser therapy (LLLT) low wattage lasers are used to irradiate the affected skin areas, joints, …

171

Low-level laser therapy versus ultrasound therapy in the treatment of subacromial impingement syndrome: a randomized clinical trial.

Yavuz F, Duman I, Taskaynatan MA, Tan AK. Yavuz F, et al. J Back Musculoskelet Rehabil. 2014;27(3):315-20. doi: 10.3233/BMR-130450. J Back Musculoskelet Rehabil. 2014. PMID: 24346151 Clinical Trial.

OBJECTIVE: The aim of this study was to compare the effectiveness of low-level laser therapy and ultrasound therapy in the treatment of subacromial impingement syndrome. MATERIALS AND METHODS: Thirty one patients with subacromial impingement syndrome w …

OBJECTIVE: The aim of this study was to compare the effectiveness of low-level laser therapy and ultrasound therapy …

172

Low level light effects on inflammatory cytokine production by rheumatoid arthritis synoviocytes.

Yamaura M, Yao M, Yaroslavsky I, Cohen R, Smotrich M, Kochevar IE. Yamaura M, et al. Lasers Surg Med. 2009 Apr;41(4):282-90. doi: 10.1002/lsm.20766. Lasers Surg Med. 2009. PMID: 19347944

BACKGROUND AND OBJECTIVE: Low level light therapy (LLLT) is being evaluated for treating chronic and acute pain associated with rheumatoid arthritis (RA) and other inflammatory diseases. ...CONCLUSIONS: The mechanism for relieving joint …

BACKGROUND AND OBJECTIVE: Low level light therapy (LLLT) is being evaluated for treating chronic and acute pa …

173

Arthralgia of the temporomandibular joint and low-level laser therapy.

Fikácková H, Dostálová T, Vosická R, Peterová V, Navrátil L, Lesák J. Fikácková H, et al. Photomed Laser Surg. 2006 Aug;24(4):522-7. doi: 10.1089/pho.2006.24.522. Photomed Laser Surg. 2006. PMID: 16942435

OBJECTIVE: This case report describes the treatment of a patient with arthralgia of the temporomandibular joint (TMJ) caused by disc displacement. BACKGROUND DATA: The goal of the treatment of TMJ arthralgia is to decrease pain by promotion of the musc …

OBJECTIVE: This case report describes the treatment of a patient with arthralgia of the temporomandibular joint (TMJ) caused b …

174

Laser therapy of painful shoulder and shoulder-hand syndrome in treatment of patients after the stroke.

Karabegović A, Kapidzić-Duraković S, Ljuca F. Karabegović A, et al. Bosn J Basic Med Sci. 2009 Feb;9(1):59-65. doi: 10.17305/bjbms.2009.2858. Bosn J Basic Med Sci. 2009. PMID: 19284397 Free PMC article. Clinical Trial.

The pain intensity in shoulder was significantly reduced in EG (p<0,0001), swelling is lowered in EG (p=0,01). ...DASH was significantly improved after LASER therapy in EG (p<0,01). EG had higher level of independency (p<0,01). LASER therapy used on …

The pain intensity in shoulder was significantly reduced in EG (p<0,0001), swelling is lowered in EG (p=0,01). ...DASH was signifi …

175

Low level laser therapy for the treatment of temporomandibular disorders: a systematic review of the literature.

Melis M, Di Giosia M, Zawawi KH. Melis M, et al. Cranio. 2012 Oct;30(4):304-12. doi: 10.1179/crn.2012.045. Cranio. 2012. PMID: 23156972 Review.

The authors performed a review of the literature to evaluate the efficacy of low level laser therapy (LLLT) for the treatment of temporomandibular disorders (TMD). ...

The authors performed a review of the literature to evaluate the efficacy of low level laser therapy (LLLT) for the tre …

176

Laser acupuncture in patients with temporomandibular dysfunction: a randomized controlled trial.

Ferreira LA, de Oliveira RG, Guimarães JP, Carvalho AC, De Paula MV. Ferreira LA, et al. Lasers Med Sci. 2013 Nov;28(6):1549-58. doi: 10.1007/s10103-013-1273-x. Epub 2013 Feb 5. Lasers Med Sci. 2013. PMID: 23380907 Clinical Trial.

Forty female subjects, ranging in age from 20 to 40 years, with diagnoses of chronic myofascial pain and arthralgia were randomly allocated to two groups: an experimental group (EG) who received the laser acupuncture as adjunct to reversible occlusal splint thera …

Forty female subjects, ranging in age from 20 to 40 years, with diagnoses of chronic myofascial pain and arthralgia were rando …

177

Effectiveness of low-level laser therapy in temporomandibular disorder.

Kulekcioglu S, Sivrioglu K, Ozcan O, Parlak M. Kulekcioglu S, et al. Scand J Rheumatol. 2003;32(2):114-8. doi: 10.1080/03009740310000139. Scand J Rheumatol. 2003. PMID: 12737331 Clinical Trial.

OBJECTIVE: To investigate the effectiveness of low-level laser therapy in the treatment of temporomandibular disorder and to compare treatment effects in myogenic and arthrogenic cases. ...In addition to a daily exercise program, all patients were treated wit …

OBJECTIVE: To investigate the effectiveness of low-level laser therapy in the treatment of temporomandibular disorder a …

178

Efficacy of low-level laser therapy in the treatment of TMDs: a meta-analysis of 14 randomised controlled trials.

Chen J, Huang Z, Ge M, Gao M. Chen J, et al. J Oral Rehabil. 2015 Apr;42(4):291-9. doi: 10.1111/joor.12258. Epub 2014 Dec 9. J Oral Rehabil. 2015. PMID: 25491183 Review.

This study was designed to evaluate the efficacy of low-level laser therapy (LLLT) in the treatment of temporomandibular disorders (TMDs). ...This study indicates that using LLLT has limited efficacy in reducing pain in patients with TMDs. However, LLL …

This study was designed to evaluate the efficacy of low-level laser therapy (LLLT) in the treatment of temporomandibula …

179

The use of low level laser therapy in the treatment of temporomandibular joint disorders. Review of the literature.

Herranz-Aparicio J, Vázquez-Delgado E, Arnabat-Domínguez J, España-Tost A, Gay-Escoda C. Herranz-Aparicio J, et al. Med Oral Patol Oral Cir Bucal. 2013 Jul 1;18(4):e603-12. doi: 10.4317/medoral.18794. Med Oral Patol Oral Cir Bucal. 2013. PMID: 23722130 Free PMC article. Review.

INTRODUCTION: The temporomandibular disorders (TMDs) have been identified as the most important cause of pain in the facial region. The low level laser therapy (LLLT) has demonstrated to have an analgesic, anti-inflammatory and biostimulating effects. …

INTRODUCTION: The temporomandibular disorders (TMDs) have been identified as the most important cause of pain in the facial region. T …

180

Management of myofascial pain: low-level laser therapy versus occlusal splints.

Öz S, Gökçen-Röhlig B, Saruhanoglu A, Tuncer EB. Öz S, et al. J Craniofac Surg. 2010 Nov;21(6):1722-8. doi: 10.1097/SCS.0b013e3181f3c76c. J Craniofac Surg. 2010. PMID: 21119408 Clinical Trial.

The present study was designed to compare the effects of low-level laser with occlusal splints in patients with signs and symptoms of myofascial pain (MP) dysfunction syndrome. ...This particular type of low-level laser therapy (820 nm, 3 …

The present study was designed to compare the effects of low-level laser with occlusal splints in patients with signs and symp …

181

Chiropractic manipulative therapy and low-level laser therapy in the management of cervical facet dysfunction: a randomized controlled study.

Saayman L, Hay C, Abrahamse H. Saayman L, et al. J Manipulative Physiol Ther. 2011 Mar-Apr;34(3):153-63. doi: 10.1016/j.jmpt.2011.02.010. J Manipulative Physiol Ther. 2011. PMID: 21492750 Clinical Trial.

PURPOSE: The aim of this study was to determine the short-term effect of chiropractic joint manipulation therapy (CMT) and low-level laser therapy (LLLT) on pain and range of motion in the management of cervical facet dysfunction. METHODS …

PURPOSE: The aim of this study was to determine the short-term effect of chiropractic joint manipulation therapy (CMT) and …

182

The short-term effects of low-level laser therapy in the management of breast-cancer-related lymphedema.

Dirican A, Andacoglu O, Johnson R, McGuire K, Mager L, Soran A. Dirican A, et al. Support Care Cancer. 2011 May;19(5):685-90. doi: 10.1007/s00520-010-0888-8. Epub 2010 May 6. Support Care Cancer. 2011. PMID: 20445997

There are some therapeutic interventions targeted to decrease the limb swelling and the associated problems. Low-level laser therapy (LLLT) has been used in the treatment of post-mastectomy lymphedema since 2007 in the US. ...All patients had experienced at l …

There are some therapeutic interventions targeted to decrease the limb swelling and the associated problems. Low-level laser …

183

Radiological and biochemical effects (CTX-II, MMP-3, 8, and 13) of low-level laser therapy (LLLT) in chronic osteoarthritis in Al-Kharj, Saudi Arabia.

S GN, Kamal W, George J, Manssor E. S GN, et al. Lasers Med Sci. 2017 Feb;32(2):297-303. doi: 10.1007/s10103-016-2114-5. Epub 2016 Dec 3. Lasers Med Sci. 2017. PMID: 27913970 Clinical Trial.

Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as biomodulatory effect on microcirculation and cartilage regeneration in animal studies. ...After 4- and 8-week treatment, active laser group shows more significant difference (p & …

Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as biomodulatory effect on microcirculati …

184

Comparative clinical study of light analgesic effect on temporomandibular disorder (TMD) using red and infrared led therapy.

Panhoca VH, Lizarelli Rde F, Nunez SC, Pizzo RC, Grecco C, Paolillo FR, Bagnato VS. Panhoca VH, et al. Lasers Med Sci. 2015 Feb;30(2):815-22. doi: 10.1007/s10103-013-1444-9. Epub 2013 Oct 3. Lasers Med Sci. 2015. PMID: 24197518 Clinical Trial.

Low-level laser therapy (LLLT) has been widely applied in pain relief in several clinical situations, including temporomandibular disorders (TMD). ...The current study showed that red and infrared LED therapy can be useful in improving outcomes …

Low-level laser therapy (LLLT) has been widely applied in pain relief in several clinical situations, including …

185

What do Cochrane Systematic Reviews say about conservative and surgical therapeutic interventions for treating rotator cuff disease? Synthesis of evidence.

Franco ESB, Puga MEDS, Imoto AM, Almeida J, Mata VD, Peccin S. Franco ESB, et al. Sao Paulo Med J. 2019 Nov-Dec;137(6):543-549. doi: 10.1590/1516-3180.2019.0275160919. Sao Paulo Med J. 2019. PMID: 32159641 Free PMC article. Review.

BACKGROUND: Shoulder pain is considered to be the third largest cause of musculoskeletal functional alterations in individuals presenting pain during movement. ...RESULTS: Thirty-one systematic reviews were included, involving comparisons between surgical procedures …

BACKGROUND: Shoulder pain is considered to be the third largest cause of musculoskeletal functional alterations in individuals presen …

186

Evaluation of low-level laser therapy in patients with acute and chronic temporomandibular disorders.

Salmos-Brito JA, de Menezes RF, Teixeira CE, Gonzaga RK, Rodrigues BH, Braz R, Bessa-Nogueira RV, Gerbi ME. Salmos-Brito JA, et al. Lasers Med Sci. 2013 Jan;28(1):57-64. doi: 10.1007/s10103-012-1065-8. Epub 2012 Feb 25. Lasers Med Sci. 2013. PMID: 22367394

The purpose of this study was to address the following question: among patients with acute or chronic temporomandibular disorders (TMD), does low-level laser therapy (LLLT) reduce pain intensity and improve maximal mouth opening? ...Low-level …

The purpose of this study was to address the following question: among patients with acute or chronic temporomandibular disorders (TMD), doe …

187

Direct Photobiomodulation Therapy on the Sciatic Nerve Significantly Attenuates Acute Nociceptive Sensitivity Without Affecting Motor Output.

Buzza AS, Cousins H, Tapas KE, Anders JJ, Lewis SJ, Jenkins MW, Moffitt MA. Buzza AS, et al. Neuromodulation. 2024 Jul 1:S1094-7159(24)00113-2. doi: 10.1016/j.neurom.2024.04.011. Online ahead of print. Neuromodulation. 2024. PMID: 38958630 Free article.

We previously established that the direct application of laser irradiation (direct photobiomodulation [PBM]) of the sural nerve reduces thermal hypersensitivity in a rodent model of chronic pain, but not mechanical hypersensitivity. ...CONCLUSIONS: These results, in …

We previously established that the direct application of laser irradiation (direct photobiomodulation [PBM]) of the sural nerve reduc …

188

Ultrasound plus low-level laser therapy for knee osteoarthritis rehabilitation: a randomized, placebo-controlled trial.

Paolillo FR, Paolillo AR, João JP, Frascá D, Duchêne M, João HA, Bagnato VS. Paolillo FR, et al. Rheumatol Int. 2018 May;38(5):785-793. doi: 10.1007/s00296-018-4000-x. Epub 2018 Feb 26. Rheumatol Int. 2018. PMID: 29480363 Clinical Trial.

This study evaluated the synergistic effects of ultrasound (US) and low-level laser therapy (LLLT) with or without therapeutic exercises (TE) in women with knee osteoarthritis. ...However, 35 women completed the full clinical trial. Pressure pain thres …

This study evaluated the synergistic effects of ultrasound (US) and low-level laser therapy (LLLT) with or without ther …

189

Short-term effects of high-intensity laser therapy, manual therapy, and Kinesio taping in patients with subacromial impingement syndrome.

Pekyavas NO, Baltaci G. Pekyavas NO, et al. Lasers Med Sci. 2016 Aug;31(6):1133-41. doi: 10.1007/s10103-016-1963-2. Epub 2016 May 25. Lasers Med Sci. 2016. PMID: 27220527 Clinical Trial.

Subacromial impingement syndrome (SAIS) is a major contributing factor of shoulder pain; and treatment approaches (Kinesio taping [KT], Exercise [EX], manual therapy [MT], and high-intensity laser therapy [HILT]) have been developed to treat the pain. …

Subacromial impingement syndrome (SAIS) is a major contributing factor of shoulder pain; and treatment approaches (Kinesio taping [KT …

190

Effects of low-power laser auriculotherapy on the physical and emotional aspects in patients with temporomandibular disorders: A blind, randomized, controlled clinical trial.

Rodrigues MDF, Rodrigues ML, Bueno KS, Aroca JP, Camilotti V, Busato MCA, Mendonça MJ. Rodrigues MDF, et al. Complement Ther Med. 2019 Feb;42:340-346. doi: 10.1016/j.ctim.2018.12.010. Epub 2018 Dec 18. Complement Ther Med. 2019. PMID: 30670264 Clinical Trial.

RESULTS: OS improved five physical symptoms of TMD (pain in the right temporal muscle, right and left masseter muscles, left joint, and left intraoral region), while LA improved six (jaw functioning; pain in left masseter muscle, right and left joints, and ri …

RESULTS: OS improved five physical symptoms of TMD (pain in the right temporal muscle, right and left masseter muscles, left joint …

191

The effect of low-level laser in knee osteoarthritis: a double-blind, randomized, placebo-controlled trial.

Hegedus B, Viharos L, Gervain M, Gálfi M. Hegedus B, et al. Photomed Laser Surg. 2009 Aug;27(4):577-84. doi: 10.1089/pho.2008.2297. Photomed Laser Surg. 2009. PMID: 19530911 Free PMC article. Clinical Trial.

INTRODUCTION: Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as a biomodulatory effect on microcirculation. ...In the placebo group, changes in joint flexion and pain were not significant. Thermographic measurement …

INTRODUCTION: Low-level laser therapy (LLLT) is thought to have an analgesic effect as well as a biomodulatory effect o …

192

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