The draft genome and transcriptome of Cannabis sativa

Genome Biol. 2011 Oct 20;12(10):R102. doi: 10.1186/gb-2011-12-10-r102.

Abstract

Background: Cannabis sativa has been cultivated throughout human history as a source of fiber, oil and food, and for its medicinal and intoxicating properties. Selective breeding has produced cannabis plants for specific uses, including high-potency marijuana strains and hemp cultivars for fiber and seed production. The molecular biology underlying cannabinoid biosynthesis and other traits of interest is largely unexplored.

Results: We sequenced genomic DNA and RNA from the marijuana strain Purple Kush using shortread approaches. We report a draft haploid genome sequence of 534 Mb and a transcriptome of 30,000 genes. Comparison of the transcriptome of Purple Kush with that of the hemp cultivar 'Finola' revealed that many genes encoding proteins involved in cannabinoid and precursor pathways are more highly expressed in Purple Kush than in 'Finola'. The exclusive occurrence of Δ9-tetrahydrocannabinolic acid synthase in the Purple Kush transcriptome, and its replacement by cannabidiolic acid synthase in 'Finola', may explain why the psychoactive cannabinoid Δ9-tetrahydrocannabinol (THC) is produced in marijuana but not in hemp. Resequencing the hemp cultivars 'Finola' and 'USO-31' showed little difference in gene copy numbers of cannabinoid pathway enzymes. However, single nucleotide variant analysis uncovered a relatively high level of variation among four cannabis types, and supported a separation of marijuana and hemp.

Conclusions: The availability of the Cannabis sativa genome enables the study of a multifunctional plant that occupies a unique role in human culture. Its availability will aid the development of therapeutic marijuana strains with tailored cannabinoid profiles and provide a basis for the breeding of hemp with improved agronomic characteristics.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Base Sequence
  • Breeding
  • Cannabis / enzymology
  • Cannabis / genetics*
  • DNA, Plant / genetics*
  • Dronabinol / metabolism
  • Flowers / genetics
  • Gene Dosage
  • Gene Expression Profiling
  • Gene Expression Regulation, Plant
  • Genome, Plant*
  • Intramolecular Oxidoreductases / genetics
  • Molecular Sequence Data
  • Polymorphism, Single Nucleotide
  • Pseudogenes
  • RNA, Plant / genetics*
  • Seeds / genetics
  • Transcriptome*

Substances

  • DNA, Plant
  • RNA, Plant
  • Dronabinol
  • Intramolecular Oxidoreductases
  • cannabidiolic acid synthase

Associated data

  • GENBANK/JP449145
  • GENBANK/JP449146
  • GENBANK/JP449147
  • GENBANK/JP449148
  • GENBANK/JP449149
  • GENBANK/JP449150
  • GENBANK/JP449151
  • GENBANK/JP449152
  • GENBANK/JP449153
  • GENBANK/JP449154
  • GENBANK/JP449155
  • GENBANK/JP449156
  • GENBANK/JP449157
  • GENBANK/JP449158
  • GENBANK/JP449159
  • GENBANK/JP449160
  • GENBANK/JP449161
  • GENBANK/JP449162
  • GENBANK/JP449163
  • GENBANK/JP449164
  • GENBANK/JP449165
  • GENBANK/JP449166
  • GENBANK/JP449167
  • GENBANK/JP449168
  • GENBANK/JP449169
  • GENBANK/JP449170
  • GENBANK/JP449171
  • GENBANK/JP449172
  • GENBANK/JP449173
  • GENBANK/JP449174
  • GENBANK/JP449175
  • GENBANK/JP449176
  • GENBANK/JP449177
  • GENBANK/JP449178
  • GENBANK/JP449179
  • GENBANK/JP449180
  • GENBANK/JP449181
  • GENBANK/JP449182
  • GENBANK/JP449183
  • GENBANK/JP449184
  • GENBANK/JP449185
  • GENBANK/JP449186
  • GENBANK/JP449187
  • GENBANK/JP449188
  • GENBANK/JP449189
  • GENBANK/JP449190
  • GENBANK/JP449191
  • GENBANK/JP449192
  • GENBANK/JP449193
  • GENBANK/JP449194
  • GENBANK/JP449195
  • GENBANK/JP449196
  • GENBANK/JP449197
  • GENBANK/JP449198
  • GENBANK/JP449199
  • GENBANK/JP449200
  • GENBANK/JP449201
  • GENBANK/JP449202
  • GENBANK/JP449203
  • GENBANK/JP449204
  • GENBANK/JP449205
  • GENBANK/JP449206
  • GENBANK/JP449207
  • GENBANK/JP449208
  • GENBANK/JP449209
  • GENBANK/JP449210
  • GENBANK/JP449211
  • GENBANK/JP449212
  • GENBANK/JP449213
  • GENBANK/JP449214
  • GENBANK/JP449215
  • GENBANK/JP449216
  • GENBANK/JP449217
  • GENBANK/JP449218
  • GENBANK/JP449219
  • GENBANK/JP449220
  • GENBANK/JP449221
  • GENBANK/JP449222
  • GENBANK/JP449223
  • GENBANK/JP449224
  • GENBANK/JP449225
  • GENBANK/JP449226
  • GENBANK/JP449227
  • GENBANK/JP449228
  • GENBANK/JP449229
  • GENBANK/JP449230
  • GENBANK/JP449231
  • GENBANK/JP449232
  • GENBANK/JP449233
  • GENBANK/JP449234
  • GENBANK/JP449235
  • GENBANK/JP449236
  • GENBANK/JP449237
  • GENBANK/JP449238
  • GENBANK/JP449239
  • GENBANK/JP449240
  • GENBANK/JP449241
  • GENBANK/JP449242
  • GENBANK/JP449243
  • GENBANK/JP449244
  • GENBANK/JP449245
  • GENBANK/JP449246
  • GENBANK/JP449247
  • GENBANK/JP449248
  • GENBANK/JP449249
  • GENBANK/JP449250
  • GENBANK/JP449251
  • GENBANK/JP449252
  • GENBANK/JP449253
  • GENBANK/JP449254
  • GENBANK/JP449255
  • GENBANK/JP449256
  • GENBANK/JP449257
  • GENBANK/JP449258
  • GENBANK/JP449259
  • GENBANK/JP449260
  • GENBANK/JP449261
  • GENBANK/JP449262
  • GENBANK/JP449263
  • GENBANK/JP449264
  • GENBANK/JP449265
  • GENBANK/JP449266
  • GENBANK/JP449267
  • GENBANK/JP449268
  • GENBANK/JP449269
  • GENBANK/JP449270
  • GENBANK/JP449271
  • GENBANK/JP449272
  • GENBANK/JP449273
  • GENBANK/JP449274
  • GENBANK/JP449275
  • GENBANK/JP449276
  • GENBANK/JP449277
  • GENBANK/JP449278
  • GENBANK/JP449279
  • GENBANK/JP449280
  • GENBANK/JP449281
  • GENBANK/JP449282
  • GENBANK/JP449283
  • GENBANK/JP449284
  • GENBANK/JP449285
  • GENBANK/JP449286
  • GENBANK/JP449287
  • GENBANK/JP449288
  • GENBANK/JP449289
  • GENBANK/JP449290
  • GENBANK/JP449291
  • GENBANK/JP449292
  • GENBANK/JP449293
  • GENBANK/JP449294
  • GENBANK/JP449295
  • GENBANK/JP449296
  • GENBANK/JP449297
  • GENBANK/JP449298
  • GENBANK/JP449299
  • GENBANK/JP449300
  • GENBANK/JP449301
  • GENBANK/JP449302
  • GENBANK/JP449303
  • GENBANK/JP449304
  • GENBANK/JP449305
  • GENBANK/JP449306
  • GENBANK/JP449307
  • GENBANK/JP449308
  • GENBANK/JP449309
  • GENBANK/JP449310
  • GENBANK/JP449311
  • GENBANK/JP449312
  • GENBANK/JP449313
  • GENBANK/JP449314
  • GENBANK/JP449315
  • GENBANK/JP449316
  • GENBANK/JP449317
  • GENBANK/JP449318
  • GENBANK/JP449319
  • GENBANK/JP449320
  • GENBANK/JP449321
  • GENBANK/JP449322
  • GENBANK/JP449323
  • GENBANK/JP449324
  • GENBANK/JP449325
  • GENBANK/JP449326
  • GENBANK/JP449327
  • GENBANK/JP449328
  • GENBANK/JP449329
  • GENBANK/JP449330
  • GENBANK/JP449331
  • GENBANK/JP449332
  • GENBANK/JP449333
  • GENBANK/JP449334
  • GENBANK/JP449335
  • GENBANK/JP449336
  • GENBANK/JP449337
  • GENBANK/JP449338
  • GENBANK/JP449339
  • GENBANK/JP449340
  • GENBANK/JP449341
  • GENBANK/JP449342
  • GENBANK/JP449343
  • GENBANK/JP449344
  • GENBANK/JP449345
  • GENBANK/JP449346
  • GENBANK/JP449347
  • GENBANK/JP449348
  • GENBANK/JP449349
  • GENBANK/JP449350
  • GENBANK/JP449351
  • GENBANK/JP449352
  • GENBANK/JP449353
  • GENBANK/JP449354
  • GENBANK/JP449355
  • GENBANK/JP449356
  • GENBANK/JP449357
  • GENBANK/JP449358
  • GENBANK/JP449359
  • GENBANK/JP449360
  • GENBANK/JP449361
  • GENBANK/JP449362
  • GENBANK/JP449363
  • GENBANK/JP449364
  • GENBANK/JP449365
  • GENBANK/JP449366
  • GENBANK/JP449367
  • GENBANK/JP449368
  • GENBANK/JP449369
  • GENBANK/JP449370
  • GENBANK/JP449371
  • GENBANK/JP449372
  • GENBANK/JP449373
  • GENBANK/JP449374
  • GENBANK/JP449375
  • GENBANK/JP449376
  • GENBANK/JP449377
  • GENBANK/JP449378
  • GENBANK/JP449379
  • GENBANK/JP449380
  • GENBANK/JP449381
  • GENBANK/JP449382
  • GENBANK/JP449383
  • GENBANK/JP449384
  • GENBANK/JP449385
  • GENBANK/JP449386
  • GENBANK/JP449387
  • GENBANK/JP449388
  • GENBANK/JP449389
  • GENBANK/JP449390
  • GENBANK/JP449391
  • GENBANK/JP449392
  • GENBANK/JP449393
  • GENBANK/JP449394
  • GENBANK/JP449395
  • GENBANK/JP449396
  • GENBANK/JP449397
  • GENBANK/JP449398
  • GENBANK/JP449399
  • GENBANK/JP449400
  • GENBANK/JP449401
  • GENBANK/JP449402
  • GENBANK/JP449403
  • GENBANK/JP449404
  • GENBANK/JP449405
  • GENBANK/JP449406
  • GENBANK/JP449407
  • GENBANK/JP449408
  • GENBANK/JP449409
  • GENBANK/JP449410
  • GENBANK/JP449411
  • GENBANK/JP449412
  • GENBANK/JP449413
  • GENBANK/JP449414
  • GENBANK/JP449415
  • GENBANK/JP449416
  • GENBANK/JP449417
  • GENBANK/JP449418
  • GENBANK/JP449419
  • GENBANK/JP449420
  • GENBANK/JP449421
  • GENBANK/JP449422
  • GENBANK/JP449423
  • GENBANK/JP449424
  • GENBANK/JP449425
  • GENBANK/JP449426
  • GENBANK/JP449427
  • GENBANK/JP449428
  • GENBANK/JP449429
  • GENBANK/JP449430
  • GENBANK/JP449431
  • GENBANK/JP449432
  • GENBANK/JP449433
  • GENBANK/JP449434
  • GENBANK/JP449435
  • GENBANK/JP449436
  • GENBANK/JP449437
  • GENBANK/JP449438
  • GENBANK/JP449439
  • GENBANK/JP449440
  • GENBANK/JP449441
  • GENBANK/JP449442
  • GENBANK/JP449443
  • GENBANK/JP449444
  • GENBANK/JP449445
  • GENBANK/JP449446
  • GENBANK/JP449447
  • GENBANK/JP449448
  • GENBANK/JP449449
  • GENBANK/JP449450
  • GENBANK/JP449451
  • GENBANK/JP449452
  • GENBANK/JP449453
  • GENBANK/JP449454
  • GENBANK/JP449455
  • GENBANK/JP449456
  • GENBANK/JP449457
  • GENBANK/JP449458
  • GENBANK/JP449459
  • GENBANK/JP449460
  • GENBANK/JP449461
  • GENBANK/JP449462
  • GENBANK/JP449463
  • GENBANK/JP449464
  • GENBANK/JP449465
  • GENBANK/JP449466
  • GENBANK/JP449467
  • GENBANK/JP449468
  • GENBANK/JP449469
  • GENBANK/JP449470
  • GENBANK/JP449471
  • GENBANK/JP449472
  • GENBANK/JP449473
  • GENBANK/JP449474
  • GENBANK/JP449475
  • GENBANK/JP449476
  • GENBANK/JP449477
  • GENBANK/JP449478
  • GENBANK/JP449479
  • GENBANK/JP449480
  • GENBANK/JP449481
  • GENBANK/JP449482
  • GENBANK/JP449483
  • GENBANK/JP449484
  • GENBANK/JP449485
  • GENBANK/JP449486
  • GENBANK/JP449487
  • GENBANK/JP449488
  • GENBANK/JP449489
  • GENBANK/JP449490
  • GENBANK/JP449491
  • GENBANK/JP449492
  • GENBANK/JP449493
  • GENBANK/JP449494
  • GENBANK/JP449495
  • GENBANK/JP449496
  • GENBANK/JP449497
  • GENBANK/JP449498
  • GENBANK/JP449499
  • GENBANK/JP449500
  • GENBANK/JP449501
  • GENBANK/JP449502
  • GENBANK/JP449503
  • GENBANK/JP449504
  • GENBANK/JP449505
  • GENBANK/JP449506
  • GENBANK/JP449507
  • GENBANK/JP449508
  • GENBANK/JP449509
  • GENBANK/JP449510
  • GENBANK/JP449511
  • GENBANK/JP449512
  • GENBANK/JP449513
  • GENBANK/JP449514
  • GENBANK/JP449515
  • GENBANK/JP449516
  • GENBANK/JP449517
  • GENBANK/JP449518
  • GENBANK/JP449519
  • GENBANK/JP449520
  • GENBANK/JP449521
  • GENBANK/JP449522
  • GENBANK/JP449523
  • GENBANK/JP449524
  • GENBANK/JP449525
  • GENBANK/JP449526
  • GENBANK/JP449527
  • GENBANK/JP449528
  • GENBANK/JP449529
  • GENBANK/JP449530
  • GENBANK/JP449531
  • GENBANK/JP449532
  • GENBANK/JP449533
  • GENBANK/JP449534
  • GENBANK/JP449535
  • GENBANK/JP449536
  • GENBANK/JP449537
  • GENBANK/JP449538
  • GENBANK/JP449539
  • GENBANK/JP449540
  • GENBANK/JP449541
  • GENBANK/JP449542
  • GENBANK/JP449543
  • GENBANK/JP449544
  • GENBANK/JP449545
  • GENBANK/JP449546
  • GENBANK/JP449547
  • GENBANK/JP449548
  • GENBANK/JP449549
  • GENBANK/JP449550
  • GENBANK/JP449551
  • GENBANK/JP449552
  • GENBANK/JP449553
  • GENBANK/JP449554
  • GENBANK/JP449555
  • GENBANK/JP449556
  • GENBANK/JP449557
  • GENBANK/JP449558
  • GENBANK/JP449559
  • GENBANK/JP449560
  • GENBANK/JP449561
  • GENBANK/JP449562
  • GENBANK/JP449563
  • GENBANK/JP449564
  • GENBANK/JP449565
  • GENBANK/JP449566
  • GENBANK/JP449567
  • GENBANK/JP449568
  • GENBANK/JP449569
  • GENBANK/JP449570
  • GENBANK/JP449571
  • GENBANK/JP449572
  • GENBANK/JP449573
  • GENBANK/JP449574
  • GENBANK/JP449575
  • GENBANK/JP449576
  • GENBANK/JP449577
  • GENBANK/JP449578
  • GENBANK/JP449579
  • GENBANK/JP449580
  • GENBANK/JP449581
  • GENBANK/JP449582
  • GENBANK/JP449583
  • GENBANK/JP449584
  • GENBANK/JP449585
  • GENBANK/JP449586
  • GENBANK/JP449587
  • GENBANK/JP449588
  • GENBANK/JP449589
  • GENBANK/JP449590
  • GENBANK/JP449591
  • GENBANK/JP449592
  • GENBANK/JP449593
  • GENBANK/JP449594
  • GENBANK/JP449595
  • GENBANK/JP449596
  • GENBANK/JP449597
  • GENBANK/JP449598
  • GENBANK/JP449599
  • GENBANK/JP449600
  • GENBANK/JP449601
  • GENBANK/JP449602
  • GENBANK/JP449603
  • GENBANK/JP449604
  • GENBANK/JP449605
  • GENBANK/JP449606
  • GENBANK/JP449607
  • GENBANK/JP449608
  • GENBANK/JP449609
  • GENBANK/JP449610
  • GENBANK/JP449611
  • GENBANK/JP449612
  • GENBANK/JP449613
  • GENBANK/JP449614
  • GENBANK/JP449615
  • GENBANK/JP449616
  • GENBANK/JP449617
  • GENBANK/JP449618
  • GENBANK/JP449619
  • GENBANK/JP449620
  • GENBANK/JP449621
  • GENBANK/JP449622
  • GENBANK/JP449623
  • GENBANK/JP449624
  • GENBANK/JP449625
  • GENBANK/JP449626
  • GENBANK/JP449627
  • GENBANK/JP449628
  • GENBANK/JP449629
  • GENBANK/JP449630
  • GENBANK/JP449631
  • GENBANK/JP449632
  • GENBANK/JP449633
  • GENBANK/JP449634
  • GENBANK/JP449635
  • GENBANK/JP449636
  • GENBANK/JP449637
  • GENBANK/JP449638
  • GENBANK/JP449639
  • GENBANK/JP449640
  • GENBANK/JP449641
  • GENBANK/JP449642
  • GENBANK/JP449643
  • GENBANK/JP449644
  • GENBANK/JP449645
  • GENBANK/JP449646
  • GENBANK/JP449647
  • GENBANK/JP449648
  • GENBANK/JP449649
  • GENBANK/JP449650
  • GENBANK/JP449651
  • GENBANK/JP449652
  • GENBANK/JP449653
  • GENBANK/JP449654
  • GENBANK/JP449655
  • GENBANK/JP449656
  • GENBANK/JP449657
  • GENBANK/JP449658
  • GENBANK/JP449659
  • GENBANK/JP449660
  • GENBANK/JP449661
  • GENBANK/JP449662
  • GENBANK/JP449663
  • GENBANK/JP449664
  • GENBANK/JP449665
  • GENBANK/JP449666
  • GENBANK/JP449667
  • GENBANK/JP449668
  • GENBANK/JP449669
  • GENBANK/JP449670
  • GENBANK/JP449671
  • GENBANK/JP449672
  • GENBANK/JP449673
  • GENBANK/JP449674
  • GENBANK/JP449675
  • GENBANK/JP449676
  • GENBANK/JP449677
  • GENBANK/JP449678
  • GENBANK/JP449679
  • GENBANK/JP449680
  • GENBANK/JP449681
  • GENBANK/JP449682
  • GENBANK/JP449683
  • GENBANK/JP449684
  • GENBANK/JP449685
  • GENBANK/JP449686
  • GENBANK/JP449687
  • GENBANK/JP449688
  • GENBANK/JP449689
  • GENBANK/JP449690
  • GENBANK/JP449691
  • GENBANK/JP449692
  • GENBANK/JP449693
  • GENBANK/JP449694
  • GENBANK/JP449695
  • GENBANK/JP449696
  • GENBANK/JP449697
  • GENBANK/JP449698
  • GENBANK/JP449699
  • GENBANK/JP449700
  • GENBANK/JP449701
  • GENBANK/JP449702
  • GENBANK/JP449703
  • GENBANK/JP449704
  • GENBANK/JP449705
  • GENBANK/JP449706
  • GENBANK/JP449707
  • GENBANK/JP449708
  • GENBANK/JP449709
  • GENBANK/JP449710
  • GENBANK/JP449711
  • GENBANK/JP449712
  • GENBANK/JP449713
  • GENBANK/JP449714
  • GENBANK/JP449715
  • GENBANK/JP449716
  • GENBANK/JP449717
  • GENBANK/JP449718
  • GENBANK/JP449719
  • GENBANK/JP449720
  • GENBANK/JP449721
  • GENBANK/JP449722
  • GENBANK/JP449723
  • GENBANK/JP449724
  • GENBANK/JP449725
  • GENBANK/JP449726
  • GENBANK/JP449727
  • GENBANK/JP449728
  • GENBANK/JP449729
  • GENBANK/JP449730
  • GENBANK/JP449731
  • GENBANK/JP449732
  • GENBANK/JP449733
  • GENBANK/JP449734
  • GENBANK/JP449735
  • GENBANK/JP449736
  • GENBANK/JP449737
  • GENBANK/JP449738
  • GENBANK/JP449739
  • GENBANK/JP449740
  • GENBANK/JP449741
  • GENBANK/JP449742
  • GENBANK/JP449743
  • GENBANK/JP449744
  • GENBANK/JP449745
  • GENBANK/JP449746
  • GENBANK/JP449747
  • GENBANK/JP449748
  • GENBANK/JP449749
  • GENBANK/JP449750
  • GENBANK/JP449751
  • GENBANK/JP449752
  • GENBANK/JP449753
  • GENBANK/JP449754
  • GENBANK/JP449755
  • GENBANK/JP449756
  • GENBANK/JP449757
  • GENBANK/JP449758
  • GENBANK/JP449759
  • GENBANK/JP449760
  • GENBANK/JP449761
  • GENBANK/JP449762
  • GENBANK/JP449763
  • GENBANK/JP449764
  • GENBANK/JP449765
  • GENBANK/JP449766
  • GENBANK/JP449767
  • GENBANK/JP449768
  • GENBANK/JP449769
  • GENBANK/JP449770
  • GENBANK/JP449771
  • GENBANK/JP449772
  • GENBANK/JP449773
  • GENBANK/JP449774
  • GENBANK/JP449775
  • GENBANK/JP449776
  • GENBANK/JP449777
  • GENBANK/JP449778
  • GENBANK/JP449779
  • GENBANK/JP449780
  • GENBANK/JP449781
  • GENBANK/JP449782
  • GENBANK/JP449783
  • GENBANK/JP449784
  • GENBANK/JP449785
  • GENBANK/JP449786
  • GENBANK/JP449787
  • GENBANK/JP449788
  • GENBANK/JP449789
  • GENBANK/JP449790
  • GENBANK/JP449791
  • GENBANK/JP449792
  • GENBANK/JP449793
  • GENBANK/JP449794
  • GENBANK/JP449795
  • GENBANK/JP449796
  • GENBANK/JP449797
  • GENBANK/JP449798
  • GENBANK/JP449799
  • GENBANK/JP449800
  • GENBANK/JP449801
  • GENBANK/JP449802
  • GENBANK/JP449803
  • GENBANK/JP449804
  • GENBANK/JP449805
  • GENBANK/JP449806
  • GENBANK/JP449807
  • GENBANK/JP449808
  • GENBANK/JP449809
  • GENBANK/JP449810
  • GENBANK/JP449811
  • GENBANK/JP449812
  • GENBANK/JP449813
  • GENBANK/JP449814
  • GENBANK/JP449815
  • GENBANK/JP449816
  • GENBANK/JP449817
  • GENBANK/JP449818
  • GENBANK/JP449819
  • GENBANK/JP449820
  • GENBANK/JP449821
  • GENBANK/JP449822
  • GENBANK/JP449823
  • GENBANK/JP449824
  • GENBANK/JP449825
  • GENBANK/JP449826
  • GENBANK/JP449827
  • GENBANK/JP449828
  • GENBANK/JP449829
  • GENBANK/JP449830
  • GENBANK/JP449831
  • GENBANK/JP449832
  • GENBANK/JP449833
  • GENBANK/JP449834
  • GENBANK/JP449835
  • GENBANK/JP449836
  • GENBANK/JP449837
  • GENBANK/JP449838
  • GENBANK/JP449839
  • GENBANK/JP449840
  • GENBANK/JP449841
  • GENBANK/JP449842
  • GENBANK/JP449843
  • GENBANK/JP449844
  • GENBANK/JP449845
  • GENBANK/JP449846
  • GENBANK/JP449847
  • GENBANK/JP449848
  • GENBANK/JP449849
  • GENBANK/JP449850
  • GENBANK/JP449851
  • GENBANK/JP449852
  • GENBANK/JP449853
  • GENBANK/JP449854
  • GENBANK/JP449855
  • GENBANK/JP449856
  • GENBANK/JP449857
  • GENBANK/JP449858
  • GENBANK/JP449859
  • GENBANK/JP449860
  • GENBANK/JP449861
  • GENBANK/JP449862
  • GENBANK/JP449863
  • GENBANK/JP449864
  • GENBANK/JP449865
  • GENBANK/JP449866
  • GENBANK/JP449867
  • GENBANK/JP449868
  • GENBANK/JP449869
  • GENBANK/JP449870
  • GENBANK/JP449871
  • GENBANK/JP449872
  • GENBANK/JP449873
  • GENBANK/JP449874
  • GENBANK/JP449875
  • GENBANK/JP449876
  • GENBANK/JP449877
  • GENBANK/JP449878
  • GENBANK/JP449879
  • GENBANK/JP449880
  • GENBANK/JP449881
  • GENBANK/JP449882
  • GENBANK/JP449883
  • GENBANK/JP449884
  • GENBANK/JP449885
  • GENBANK/JP449886
  • GENBANK/JP449887
  • GENBANK/JP449888
  • GENBANK/JP449889
  • GENBANK/JP449890
  • GENBANK/JP449891
  • GENBANK/JP449892
  • GENBANK/JP449893
  • GENBANK/JP449894
  • GENBANK/JP449895
  • GENBANK/JP449896
  • GENBANK/JP449897
  • GENBANK/JP449898
  • GENBANK/JP449899
  • GENBANK/JP449900
  • GENBANK/JP449901
  • GENBANK/JP449902
  • GENBANK/JP449903
  • GENBANK/JP449904
  • GENBANK/JP449905
  • GENBANK/JP449906
  • GENBANK/JP449907
  • GENBANK/JP449908
  • GENBANK/JP449909
  • GENBANK/JP449910
  • GENBANK/JP449911
  • GENBANK/JP449912
  • GENBANK/JP449913
  • GENBANK/JP449914
  • GENBANK/JP449915
  • GENBANK/JP449916
  • GENBANK/JP449917
  • GENBANK/JP449918
  • GENBANK/JP449919
  • GENBANK/JP449920
  • GENBANK/JP449921
  • GENBANK/JP449922
  • GENBANK/JP449923
  • GENBANK/JP449924
  • GENBANK/JP449925
  • GENBANK/JP449926
  • GENBANK/JP449927
  • GENBANK/JP449928
  • GENBANK/JP449929
  • GENBANK/JP449930
  • GENBANK/JP449931
  • GENBANK/JP449932
  • GENBANK/JP449933
  • GENBANK/JP449934
  • GENBANK/JP449935
  • GENBANK/JP449936
  • GENBANK/JP449937
  • GENBANK/JP449938
  • GENBANK/JP449939
  • GENBANK/JP449940
  • GENBANK/JP449941
  • GENBANK/JP449942
  • GENBANK/JP449943
  • GENBANK/JP449944
  • GENBANK/JP449945
  • GENBANK/JP449946
  • GENBANK/JP449947
  • GENBANK/JP449948
  • GENBANK/JP449949
  • GENBANK/JP449950
  • GENBANK/JP449951
  • GENBANK/JP449952
  • GENBANK/JP449953
  • GENBANK/JP449954
  • GENBANK/JP449955
  • GENBANK/JP449956
  • GENBANK/JP449957
  • GENBANK/JP449958
  • GENBANK/JP449959
  • GENBANK/JP449960
  • GENBANK/JP449961
  • GENBANK/JP449962
  • GENBANK/JP449963
  • GENBANK/JP449964
  • GENBANK/JP449965
  • GENBANK/JP449966
  • GENBANK/JP449967
  • GENBANK/JP449968
  • GENBANK/JP449969
  • GENBANK/JP449970
  • GENBANK/JP449971
  • GENBANK/JP449972
  • GENBANK/JP449973
  • GENBANK/JP449974
  • GENBANK/JP449975
  • GENBANK/JP449976
  • GENBANK/JP449977
  • GENBANK/JP449978
  • GENBANK/JP449979
  • GENBANK/JP449980
  • GENBANK/JP449981
  • GENBANK/JP449982
  • GENBANK/JP449983
  • GENBANK/JP449984
  • GENBANK/JP449985
  • GENBANK/JP449986
  • GENBANK/JP449987
  • GENBANK/JP449988
  • GENBANK/JP449989
  • GENBANK/JP449990
  • GENBANK/JP449991
  • GENBANK/JP449992
  • GENBANK/JP449993
  • GENBANK/JP449994
  • GENBANK/JP449995
  • GENBANK/JP449996
  • GENBANK/JP449997
  • GENBANK/JP449998
  • GENBANK/JP449999
  • GENBANK/JP450000
  • GENBANK/JP450001
  • GENBANK/JP450002
  • GENBANK/JP450003
  • GENBANK/JP450004
  • GENBANK/JP450005
  • GENBANK/JP450006
  • GENBANK/JP450007
  • GENBANK/JP450008
  • GENBANK/JP450009
  • GENBANK/JP450010
  • GENBANK/JP450011
  • GENBANK/JP450012
  • GENBANK/JP450013
  • GENBANK/JP450014
  • GENBANK/JP450015
  • GENBANK/JP450016
  • GENBANK/JP450017
  • GENBANK/JP450018
  • GENBANK/JP450019
  • GENBANK/JP450020
  • GENBANK/JP450021
  • GENBANK/JP450022
  • GENBANK/JP450023
  • GENBANK/JP450024
  • GENBANK/JP450025
  • GENBANK/JP450026
  • GENBANK/JP450027
  • GENBANK/JP450028
  • GENBANK/JP450029
  • GENBANK/JP450030
  • GENBANK/JP450031
  • GENBANK/JP450032
  • GENBANK/JP450033
  • GENBANK/JP450034
  • GENBANK/JP450035
  • GENBANK/JP450036
  • GENBANK/JP450037
  • GENBANK/JP450038
  • GENBANK/JP450039
  • GENBANK/JP450040
  • GENBANK/JP450041
  • GENBANK/JP450042
  • GENBANK/JP450043
  • GENBANK/JP450044
  • GENBANK/JP450045
  • GENBANK/JP450046
  • GENBANK/JP450047
  • GENBANK/JP450048
  • GENBANK/JP450049
  • GENBANK/JP450050
  • GENBANK/JP450051
  • GENBANK/JP450052
  • GENBANK/JP450053
  • GENBANK/JP450054
  • GENBANK/JP450055
  • GENBANK/JP450056
  • GENBANK/JP450057
  • GENBANK/JP450058
  • GENBANK/JP450059
  • GENBANK/JP450060
  • GENBANK/JP450061
  • GENBANK/JP450062
  • GENBANK/JP450063
  • GENBANK/JP450064
  • GENBANK/JP450065
  • GENBANK/JP450066
  • GENBANK/JP450067
  • GENBANK/JP450068
  • GENBANK/JP450069
  • GENBANK/JP450070
  • GENBANK/JP450071
  • GENBANK/JP450072
  • GENBANK/JP450073
  • GENBANK/JP450074
  • GENBANK/JP450075
  • GENBANK/JP450076
  • GENBANK/JP450077
  • GENBANK/JP450078
  • GENBANK/JP450079
  • GENBANK/JP450080
  • GENBANK/JP450081
  • GENBANK/JP450082
  • GENBANK/JP450083
  • GENBANK/JP450084
  • GENBANK/JP450085
  • GENBANK/JP450086
  • GENBANK/JP450087
  • GENBANK/JP450088
  • GENBANK/JP450089
  • GENBANK/JP450090
  • GENBANK/JP450091
  • GENBANK/JP450092
  • GENBANK/JP450093
  • GENBANK/JP450094
  • GENBANK/JP450095
  • GENBANK/JP450096
  • GENBANK/JP450097
  • GENBANK/JP450098
  • GENBANK/JP450099
  • GENBANK/JP450100
  • GENBANK/JP450101
  • GENBANK/JP450102
  • GENBANK/JP450103
  • GENBANK/JP450104
  • GENBANK/JP450105
  • GENBANK/JP450106
  • GENBANK/JP450107
  • GENBANK/JP450108
  • GENBANK/JP450109
  • GENBANK/JP450110
  • GENBANK/JP450111
  • GENBANK/JP450112
  • GENBANK/JP450113
  • GENBANK/JP450114
  • GENBANK/JP450115
  • GENBANK/JP450116
  • GENBANK/JP450117
  • GENBANK/JP450118
  • GENBANK/JP450119
  • GENBANK/JP450120
  • GENBANK/JP450121
  • GENBANK/JP450122
  • GENBANK/JP450123
  • GENBANK/JP450124
  • GENBANK/JP450125
  • GENBANK/JP450126
  • GENBANK/JP450127
  • GENBANK/JP450128
  • GENBANK/JP450129
  • GENBANK/JP450130
  • GENBANK/JP450131
  • GENBANK/JP450132
  • GENBANK/JP450133
  • GENBANK/JP450134
  • GENBANK/JP450135
  • GENBANK/JP450136
  • GENBANK/JP450137
  • GENBANK/JP450138
  • GENBANK/JP450139
  • GENBANK/JP450140
  • GENBANK/JP450141
  • GENBANK/JP450142
  • GENBANK/JP450143
  • GENBANK/JP450144