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JNK is involved in signal integration during costimulation of T lymphocytes.
Su B, Jacinto E, Hibi M, Kallunki T, Karin M, Ben-Neriah Y. Su B, et al. Cell. 1994 Jun 3;77(5):727-36. doi: 10.1016/0092-8674(94)90056-6. Cell. 1994. PMID: 8205621
TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.
Jacinto E, Guo B, Arndt KT, Schmelzle T, Hall MN. Jacinto E, et al. Mol Cell. 2001 Nov;8(5):1017-26. doi: 10.1016/s1097-2765(01)00386-0. Mol Cell. 2001. PMID: 11741537
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Jacinto E, Loewith R, Schmidt A, Lin S, Rüegg MA, Hall A, Hall MN. Jacinto E, et al. Nat Cell Biol. 2004 Nov;6(11):1122-8. doi: 10.1038/ncb1183. Epub 2004 Oct 3. Nat Cell Biol. 2004. PMID: 15467718
Phosphatase targets in TOR signaling.
Jacinto E. Jacinto E. Methods Mol Biol. 2007;365:323-34. doi: 10.1385/1-59745-267-X:323. Methods Mol Biol. 2007. PMID: 17200572
TOR regulation of AGC kinases in yeast and mammals.
Jacinto E, Lorberg A. Jacinto E, et al. Biochem J. 2008 Feb 15;410(1):19-37. doi: 10.1042/BJ20071518. Biochem J. 2008. PMID: 18215152 Review.
What controls TOR?
Jacinto E. Jacinto E. IUBMB Life. 2008 Aug;60(8):483-96. doi: 10.1002/iub.56. IUBMB Life. 2008. PMID: 18493947 Review.
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
Facchinetti V, Ouyang W, Wei H, Soto N, Lazorchak A, Gould C, Lowry C, Newton AC, Mao Y, Miao RQ, Sessa WC, Qin J, Zhang P, Su B, Jacinto E. Facchinetti V, et al. EMBO J. 2008 Jul 23;27(14):1932-43. doi: 10.1038/emboj.2008.120. Epub 2008 Jun 19. EMBO J. 2008. PMID: 18566586 Free PMC article.
mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Oh WJ, Wu CC, Kim SJ, Facchinetti V, Julien LA, Finlan M, Roux PP, Su B, Jacinto E. Oh WJ, et al. EMBO J. 2010 Dec 1;29(23):3939-51. doi: 10.1038/emboj.2010.271. Epub 2010 Nov 2. EMBO J. 2010. PMID: 21045808 Free PMC article.
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