Jackman AL - Search Results

1

Modulation of anti-metabolite effects. Effects of thymidine on the efficacy of the quinazoline-based thymidylate synthetase inhibitor, CB3717.

Jackman AL, Taylor GA, Calvert AH, Harrap KR. Jackman AL, et al. Biochem Pharmacol. 1984 Oct 15;33(20):3269-75. doi: 10.1016/0006-2952(84)90089-3. Biochem Pharmacol. 1984. PMID: 6487375

2

Selective delivery of CB300638, a cyclopenta[g]quinazoline-based thymidylate synthase inhibitor into human tumor cell lines overexpressing the alpha-isoform of the folate receptor.

Theti DS, Bavetsias V, Skelton LA, Titley J, Gibbs D, Jansen G, Jackman AL. Theti DS, et al. Among authors: jackman al. Cancer Res. 2003 Jul 1;63(13):3612-8. Cancer Res. 2003. PMID: 12839949

3

The renal effects of the water-soluble, non-folylpolyglutamate synthetase-dependent thymidylate synthase inhibitor ZD9331 in mice.

Walton MI, Mitchell F, Aherne GW, Medlow CJ, Boyle FT, Jackman AL. Walton MI, et al. Among authors: jackman al. Br J Cancer. 1998 Dec;78(11):1457-63. doi: 10.1038/bjc.1998.707. Br J Cancer. 1998. PMID: 9836478 Free PMC article.

4

Preclinical pharmacology of CB30900, a novel dipeptide inhibitor of thymidylate synthase, in mice.

Walton MI, Gibson W, Aherne GW, Lawrence N, Stephens TC, Smith MN, Jackman AL. Walton MI, et al. Among authors: jackman al. J Pharmacol Exp Ther. 1996 May;277(2):909-16. J Pharmacol Exp Ther. 1996. PMID: 8627573

5

Folate-based thymidylate synthase inhibitors as anticancer drugs.

Jackman AL, Calvert AH. Jackman AL, et al. Ann Oncol. 1995 Nov;6(9):871-81. doi: 10.1093/oxfordjournals.annonc.a059353. Ann Oncol. 1995. PMID: 8624289 Review.

6

The measurement of polyglutamate metabolites of the thymidylate synthase inhibitor, ICI D1694, in mouse and human cultured cells.

Gibson W, Bisset GM, Marsham PR, Kelland LR, Judson IR, Jackman AL. Gibson W, et al. Among authors: jackman al. Biochem Pharmacol. 1993 Feb 24;45(4):863-9. doi: 10.1016/0006-2952(93)90170-2. Biochem Pharmacol. 1993. PMID: 7680860

7

Molecular characterisation of two cell lines selected for resistance to the folate-based thymidylate synthase inhibitor, ZD1694.

Freemantle SJ, Jackman AL, Kelland LR, Calvert AH, Lunec J. Freemantle SJ, et al. Among authors: jackman al. Br J Cancer. 1995 May;71(5):925-30. doi: 10.1038/bjc.1995.179. Br J Cancer. 1995. PMID: 7537519 Free PMC article.

8

ICI D1694, an inhibitor of thymidylate synthase for clinical study.

Jackman AL, Jodrell DI, Gibson W, Stephens TC. Jackman AL, et al. Adv Exp Med Biol. 1991;309A:19-23. doi: 10.1007/978-1-4899-2638-8_4. Adv Exp Med Biol. 1991. PMID: 1789205

9

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.

Westerhof GR, Schornagel JH, Kathmann I, Jackman AL, Rosowsky A, Forsch RA, Hynes JB, Boyle FT, Peters GJ, Pinedo HM, et al. Westerhof GR, et al. Among authors: jackman al. Mol Pharmacol. 1995 Sep;48(3):459-71. Mol Pharmacol. 1995. PMID: 7565626

10

The in vivo metabolic stability of dipeptide analogues of the quinazoline antifolate, ICI 198583, in mice.

Jodrell DI, Gibson W, Bisset GM, Boyle FT, Judson IR, Jackman AL. Jodrell DI, et al. Among authors: jackman al. Biochem Pharmacol. 1993 Dec 14;46(12):2229-34. doi: 10.1016/0006-2952(93)90613-2. Biochem Pharmacol. 1993. PMID: 8274156

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