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Progesterone induces adult mammary stem cell expansion.
Joshi PA, Jackson HW, Beristain AG, Di Grappa MA, Mote PA, Clarke CL, Stingl J, Waterhouse PD, Khokha R. Joshi PA, et al. Among authors: jackson hw. Nature. 2010 Jun 10;465(7299):803-7. doi: 10.1038/nature09091. Nature. 2010. PMID: 20445538
Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state.
Shimoda M, Principe S, Jackson HW, Luga V, Fang H, Molyneux SD, Shao YW, Aiken A, Waterhouse PD, Karamboulas C, Hess FM, Ohtsuka T, Okada Y, Ailles L, Ludwig A, Wrana JL, Kislinger T, Khokha R. Shimoda M, et al. Among authors: jackson hw. Nat Cell Biol. 2014 Sep;16(9):889-901. doi: 10.1038/ncb3021. Epub 2014 Aug 24. Nat Cell Biol. 2014. PMID: 25150980
RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1.
Joshi PA, Waterhouse PD, Kannan N, Narala S, Fang H, Di Grappa MA, Jackson HW, Penninger JM, Eaves C, Khokha R. Joshi PA, et al. Among authors: jackson hw. Stem Cell Reports. 2015 Jul 14;5(1):31-44. doi: 10.1016/j.stemcr.2015.05.012. Epub 2015 Jun 18. Stem Cell Reports. 2015. PMID: 26095608 Free PMC article.
Tumor suppression by stromal TIMPs.
Shimoda M, Jackson HW, Khokha R. Shimoda M, et al. Among authors: jackson hw. Mol Cell Oncol. 2016 Mar 30;3(3):e975082. doi: 10.4161/23723556.2014.975082. eCollection 2016 May. Mol Cell Oncol. 2016. PMID: 27314104 Free PMC article.
TIMPs: versatile extracellular regulators in cancer.
Jackson HW, Defamie V, Waterhouse P, Khokha R. Jackson HW, et al. Nat Rev Cancer. 2017 Jan;17(1):38-53. doi: 10.1038/nrc.2016.115. Epub 2016 Dec 9. Nat Rev Cancer. 2017. PMID: 27932800 Review.
A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland.
Shiah YJ, Tharmapalan P, Casey AE, Joshi PA, McKee TD, Jackson HW, Beristain AG, Chan-Seng-Yue MA, Bader GD, Lydon JP, Waterhouse PD, Boutros PC, Khokha R. Shiah YJ, et al. Among authors: jackson hw. Stem Cell Reports. 2015 Mar 10;4(3):313-322. doi: 10.1016/j.stemcr.2015.01.011. Epub 2015 Feb 19. Stem Cell Reports. 2015. PMID: 28447939 Free PMC article.
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.
Li L, Guturi KKN, Gautreau B, Patel PS, Saad A, Morii M, Mateo F, Palomero L, Barbour H, Gomez A, Ng D, Kotlyar M, Pastrello C, Jackson HW, Khokha R, Jurisica I, Affar EB, Raught B, Sanchez O, Alaoui-Jamali M, Pujana MA, Hakem A, Hakem R. Li L, et al. Among authors: jackson hw. J Clin Invest. 2018 Oct 1;128(10):4525-4542. doi: 10.1172/JCI120401. Epub 2018 Aug 2. J Clin Invest. 2018. PMID: 30222135 Free PMC article.
31 results