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Deubiquitylating enzymes and drug discovery: emerging opportunities.
Harrigan JA, Jacq X, Martin NM, Jackson SP. Harrigan JA, et al. Among authors: jackson sp. Nat Rev Drug Discov. 2018 Jan;17(1):57-78. doi: 10.1038/nrd.2017.152. Epub 2017 Sep 29. Nat Rev Drug Discov. 2018. PMID: 28959952 Free PMC article. Review.
MDC1 is required for the intra-S-phase DNA damage checkpoint.
Goldberg M, Stucki M, Falck J, D'Amours D, Rahman D, Pappin D, Bartek J, Jackson SP. Goldberg M, et al. Among authors: jackson sp. Nature. 2003 Feb 27;421(6926):952-6. doi: 10.1038/nature01445. Nature. 2003. PMID: 12607003
A DNA damage checkpoint response in telomere-initiated senescence.
d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, Jackson SP. d'Adda di Fagagna F, et al. Among authors: jackson sp. Nature. 2003 Nov 13;426(6963):194-8. doi: 10.1038/nature02118. Epub 2003 Nov 5. Nature. 2003. PMID: 14608368
A means to a DNA end: the many roles of Ku.
Downs JA, Jackson SP. Downs JA, et al. Among authors: jackson sp. Nat Rev Mol Cell Biol. 2004 May;5(5):367-78. doi: 10.1038/nrm1367. Nat Rev Mol Cell Biol. 2004. PMID: 15122350 Review. No abstract available.
Human CtIP promotes DNA end resection.
Sartori AA, Lukas C, Coates J, Mistrik M, Fu S, Bartek J, Baer R, Lukas J, Jackson SP. Sartori AA, et al. Among authors: jackson sp. Nature. 2007 Nov 22;450(7169):509-14. doi: 10.1038/nature06337. Epub 2007 Oct 28. Nature. 2007. PMID: 17965729 Free PMC article.
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