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Evaluation of the in vivo anti-inflammatory and analgesic and in vitro anti-cancer activities of curcumin and its derivatives.
Jacob JN, Badyal DK, Bala S, Toloue M. Jacob JN, et al. Nat Prod Commun. 2013 Mar;8(3):359-62. Nat Prod Commun. 2013. PMID: 23678811
Glucose-aspirin: Synthesis and in vitro anti-cancer activity studies.
Jacob JN, Tazawa MJ. Jacob JN, et al. Bioorg Med Chem Lett. 2012 May 1;22(9):3168-71. doi: 10.1016/j.bmcl.2012.03.053. Epub 2012 Mar 23. Bioorg Med Chem Lett. 2012. PMID: 22494617
Evaluation of the in vivo anti-inflammatory and analgesic activity of a highly water-soluble aspirin conjugate.
Jacob JN, Badyal DK, Bala S. Jacob JN, et al. Basic Clin Pharmacol Toxicol. 2013 Mar;112(3):171-4. doi: 10.1111/bcpt.12006. Epub 2012 Oct 9. Basic Clin Pharmacol Toxicol. 2013. PMID: 22963282 Free article.
Biological studies of turmeric oil, part 3: anti-inflammatory and analgesic properties of turmeric oil and fish oil in comparison with aspirin.
Jacob JN, Badyal DK. Jacob JN, et al. Nat Prod Commun. 2014 Feb;9(2):225-8. Nat Prod Commun. 2014. PMID: 24689297
Dopaminergic (4aR,10bS)-cis- and (4aS,10bS)-trans-octahydrobenzo[F]quinolines have similar pharmacophores.
Froimowitz M, Deng Y, Jacob JN, Li N, Cody V. Froimowitz M, et al. Among authors: jacob jn. Drug Des Discov. 1995 Aug;13(1):73-81. Drug Des Discov. 1995. PMID: 8882902
Synthesis, brain uptake, and pharmacological properties of a glyceryl lipid containing GABA and the GABA-T inhibitor gamma-vinyl-GABA.
Jacob JN, Hesse GW, Shashoua VE. Jacob JN, et al. J Med Chem. 1990 Feb;33(2):733-6. doi: 10.1021/jm00164a042. J Med Chem. 1990. PMID: 2299639
Uptake in brain and neurophysiological activity of two lipid esters of gamma-aminobutyric acid.
Hesse GW, Jacob JN, Shashoua VE. Hesse GW, et al. Among authors: jacob jn. Neuropharmacology. 1988 Jun;27(6):637-40. doi: 10.1016/0028-3908(88)90186-4. Neuropharmacology. 1988. PMID: 3419546
gamma-Aminobutyric acid esters. 3. Synthesis, brain uptake, and pharmacological properties of C-18 glyceryl lipid esters of GABA with varying degree of unsaturation.
Jacob JN, Hesse GW, Shashoua VE. Jacob JN, et al. J Med Chem. 1987 Sep;30(9):1573-6. doi: 10.1021/jm00392a008. J Med Chem. 1987. PMID: 3625705
Inhibitory effect of cholesteryl gamma-aminobutyrate on evoked activity in rat hippocampal slices.
Hesse GW, Shashoua VE, Jacob JN. Hesse GW, et al. Among authors: jacob jn. Neuropharmacology. 1985 Feb;24(2):139-46. doi: 10.1016/0028-3908(85)90173-x. Neuropharmacology. 1985. PMID: 2986031
gamma-Aminobutyric acid esters. 2. Synthesis, brain uptake, and pharmacological properties of lipid esters of gamma-aminobutyric acid.
Jacob JN, Shashoua VE, Campbell A, Baldessarini RJ. Jacob JN, et al. J Med Chem. 1985 Jan;28(1):106-10. doi: 10.1021/jm00379a019. J Med Chem. 1985. PMID: 3965703
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